Results 241 to 250 of about 97,922 (342)

Oromandibular Dystonia and Dysphagia in Hyperglycemic Brainstem Dysfunction. [PDF]

Tremor Other Hyperkinet Mov (N Y)
Lueg G, Westhoff T, Fruth M, Kerkmann R, Krämer J.   +4 more
europepmc   +1 more source

Acidic Nanoparticles Prevent HIV Pre‐Exposure Prophylaxis (PrEP)‐Induced Oligodendrocyte Impairments by Restoring Lysosomal pH in Adolescent Models

Glia, Volume 73, Issue 10, Page 1967-1988, October 2025.
Main Points Pre‐exposure prophylaxis (PrEP) inhibits oligodendrocyte differentiation PrEP inhibits oligodendrocyte differentiation through lysosome deacidification Acidic nanoparticles prevent PrEP‐induced inhibition of oligodendrocyte differentiation ABSTRACT A disproportionate percentage of adolescents are diagnosed with human immunodeficiency virus (
Caela C. Long, Lindsay K. Festa, Melanie Cruz‐Berrios, Teshawn D. Johnson, Claire H. Mitchell, Kelly L. Jordan‐Sciutto, Judith B. Grinspan   +6 more
wiley   +1 more source

Diverse Subpopulations of Reactive Astrocytes Following Chronic Toxoplasma Infection

Glia, Volume 73, Issue 10, Page 2003-2024, October 2025.
Main Points Toxoplasma infection results in distinct astrocyte subpopulations. Chronically labeled reactive astrocytes appear transcriptionally plastic and can regain acute inflammatory responding and naive homeostatic astrocytic gene patterns in the presence of ongoing neuroinflammation.
Zoe A. Figueroa, Jose L. Martin, Arzu Ulu, William Agnew‐Svoboda, Teresa Ubina, Martin M. Riccomagno, Todd A. Fiacco, Emma H. Wilson   +7 more
wiley   +1 more source

TREM2 regulates microglial cell activation in response to demyelination in vivo

Acta Neuropathologica, 2015
C. Cantoni, Bryan Bollman, Danilo Licastro, M. Xie, Robert Mikesell, R. Schmidt, Carla M. Yuede, D. Galimberti, G. Olivecrona, R. Klein, A. Cross, K. Otero, L. Piccio   +12 more
semanticscholar   +1 more source

Microglial Activation and Inflammatory Responses in Parkinson's Disease Models Are Attenuated by TRPM2 Depletion

Glia, Volume 73, Issue 10, Page 2035-2056, October 2025.
Main Points Trpm2 partial and complete knockout reduce neuroinflammation in male and female mice. Microglial morphological changes are not found in Trpm2 knockout 6‐OHDA‐induced mice. TRPM2 is involved in microglial phagocytosis and IL1β, IL6, and iNOS expression. ABSTRACT Inflammation, and particularly microglial cells, has become a central feature in
Ana Flávia F. Ferreira, Zhong‐Ping Feng, Hong‐Shuo Sun, Luiz Roberto G. Britto   +3 more
wiley   +1 more source

Hemi-capsulo-rhombencephalic demyelination

Annals of Indian Academy of Neurology, 2010
Suresh Chandran C, Maheshwaran V, Unni Madhavan   +2 more
doaj  

Osmotic demyelination syndrome: A pediatric case report and a systematic literature review. [PDF]

Radiol Case Rep
Mouhcine Y, Ezzoulali Z, Ouazzani H, Chaouche I, Akammar A, Bouardi NE, Alami B, Lamrani YA, Maaroufi M, Boubbou M.   +9 more
europepmc   +1 more source

The Therapeutic Potential of Andrographolide and Its Derivatives in Inflammatory Diseases

Pharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
ABSTRACT Andrographolide, a diterpenoid component found in traditional Chinese medicine Andrographis paniculata, is known as a natural antibiotic and can be used to treat inflammatory lesions of various systemic diseases. In recent years, andrographolide derivatives have been continuously synthesized and have shown good anti‐inflammatory ...
Xiaoqin Shan, Siyi Li, Jiayi Liu, Can Wang, Yao Wei, Jiayi Shi, Xinyue Zhang, Lili Gu   +7 more
wiley   +1 more source

Osmotic Demyelination Syndrome in Hyperosmolar Hyperglycemic State With Contrasting Initial Sodium Levels: A Report of Two Cases. [PDF]

Cureus
Kasamatsu D, Tsunemitsu T, Matsumoto M, Suzuki T.   +3 more
europepmc   +1 more source

Synthetic microneurotrophins: Neurotrophin receptors for therapeutics of neurodegenerative diseases

British Journal of Pharmacology, Volume 182, Issue 19, Page 4466-4489, October 2025.
Neurodegenerative disorders are characterised by the chronic progressive degeneration of specific neuronal subtypes, neuroinflammation, myelin damage and synaptic loss. Despite their growing incidence, advancements in effective treatments remain limited, because of lack of knowledge for the aetiology of the diverse pathophysiology to design systematic ...
Ioanna Zota, Theodora Calogeropoulou, Konstantina Chanoumidou, Ioannis Charalampopoulos, Achille Gravanis   +4 more
wiley   +1 more source