Results 111 to 120 of about 43,848 (310)

Systematic and Bibliometric Analysis of Magnetite Nanoparticles and Their Applications in (Biomedical) Research

Global Challenges, Volume 7, Issue 1, January 2023., 2023
Bibliometric and systematic analysis shows research from 1990 to 2020 reveals the versatility of magnetite nanoparticles and their evolving usage in a number of fields. Initially focusing on the environmental and industrial applications, to the biomedical applications. However, recent research highlights their toxicity and potential detrimental effects
Charlotte L. Fleming, Mojtaba Golzan, Cindy Gunawan, Kristine C. McGrath   +3 more
wiley   +1 more source

Thermally activated delayed fluorescence carbazole‐triazine dendrimer with bulky substituents

Aggregate
Carbazole‐triazine dendrimers with a bulky terminal substituent were synthesized, and the thermally activated delayed fluorescence (TADF) property was investigated.
Hiroki Ikebe, Kohei Nakao, Eri Hisamura, Minori Furukori, Yasuo Nakayama, Takuya Hosokai, Minlang Yang, Guanting Liu, Takuma Yasuda, Ken Albrecht   +9 more
doaj   +1 more source

Molecular Irregularity Indices of Nanostar, Fullerene, and Polymer Dendrimers

Journal of Chemistry, 2020
Dendrimers are highly branched organic macromolecules with successive layers of branch units surrounding a central core. Some properties like toxicity, entropy, and heats of vaporization of these dendrimers can be forecasted using topological indices ...
Xie Qing, Zhen Wang, Mobeen Munir, Haseeb Ahmad   +3 more
doaj   +1 more source

OcuPair, a Novel Photo‐crosslinkable PAMAM Dendrimer‐Hyaluronic Acid Hydrogel Bandage/Bioadhesive for Corneal Injuries and Temporary Corneal Repair

Advanced Science, EarlyView.
A schematic diagram showing the OcuPair adhesive hydrogel formulation loaded into the final delivery device and applied over the full‐thickness corneal wound in an in vivo rabbit model of corneal injury followed by in situ crosslinking to form a transparent hydrogel bandage sealing the wound.
Siva P. Kambhampati, Rishi Sharma, Hui Lin, Santiago Appiani, Jeffrey L. Cleland, Samuel C. Yiu, Rangaramanujam M. Kannan   +6 more
wiley   +1 more source

KK2DP7 Stimulates CD11b+ Cell Populations in the Spleen to Elicit Trained Immunity for Anti‐Tumor Therapy

Advanced Science, EarlyView.
This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang, Lin Tang, Yusi Wang, Xuejing Zhou, Zhenyu Ding, Li Yang   +5 more
wiley   +1 more source

Dynamic responsiveness of self‐assembling peptide‐based nano‐drug systems

Interdisciplinary Medicine, Volume 1, Issue 1, January 2023., 2023
This review discusses dynamically responsive self‐assembling peptide‐based nano‐drug systems, including the stimulation response, strategy of biomimicry, subcellular internalization, and the applications of peptide nano‐drug materials, and concludes with a brief outlook of their challenges and opportunities in clinical translation.
Yuhan Wang, Jie Zhan, Jinyan Huang, Xing Wang, Zehong Chen, Zhimou Yang, Jie Li   +6 more
wiley   +1 more source

Syntheses of Sulfo-Glycodendrimers Using Click Chemistry and Their Biological Evaluation

Molecules, 2012
A series of novel glycol-clusters containing sulfonated N-acetyl-D-glucosamine (GlcNAc) have been synthesized using click chemistry. Three dendrimers with aromatic dendrons were synthesized using chlorination, azidation and click chemistries.
Tomohiro Fukuda, Yoshiko Miura, Shunsuke Onogi   +2 more
doaj   +1 more source

Dendrimers for theranostic applications

Biomolecular Concepts, 2015
AbstractRecently, there have been tremendous advances in the development of various nanotechnology-based platforms for diagnosis and therapy. These nanoplatforms, which include liposomes, micelles, polymers, and dendrimers, comprise highly integrated nanoparticles that provide multiple functions, such as targeting, imaging, and therapy.
Chie Kojima, Ugir Hossain Sk
openaire   +4 more sources

Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model

Proceedings of the National Academy of Sciences of the United States of America, 2016
Significance Liver cancer is a leading cause of death and a global health problem. Unfortunately, five small-molecule drugs for hepatocellular carcinoma (HCC) recently failed phase III clinical trials partly because late-stage liver dysfunction amplifies
Kejin Zhou, Liem H. Nguyen, Jason B Miller, Yunfeng Yan, P. Kos, Hu Xiong, Lin Li, Jing Hao, Jonathan T Minnig, Hao Zhu, D. Siegwart   +10 more
semanticscholar   +1 more source

Phototherapy via Modulation of β‐Amyloid in Combating Alzheimer's Disease

Aggregate, EarlyView.
This review introduces the light‐regulated Aβ aggregation, highlighting four applications: photodynamic therapy (PDT), photothermal therapy (PTT), photopharmacology, and photobiomodulation (PBM) systems. It also summarizes the current issues and proposes the prospects of photo‐induced modulation of Aβ aggregation and clearance as a therapeutic strategy
Yunhua Zhang, Chengyuan Qian, Yuncong Chen, Weijiang He, Zijian Guo   +4 more
wiley   +1 more source