Results 121 to 130 of about 43,848 (310)
Progress and challenges of mRNA vaccines
Interdisciplinary Medicine, Volume 1, Issue 1, January 2023., 2023 As the third‐generation nucleic acid vaccine, the Messenger RNA (mRNA) vaccine stimulates a specific immune response by introducing mRNA expressing the target antigen into the body through a specific delivery system and expressing the corresponding protein.
Liangru Lin +3 more
wiley +1 more source
High Fluorescent Porphyrin-PAMAM-Fluorene Dendrimers
Molecules, 2015 Two new classes of dendrimers bearing 8 and 32 fluorene donor groups have been synthesized. The first and second generations of these porphyrin-PAMAM-fluorene dendrimers were characterized by 1H-NMR, 13C-NMR, FTIR, UV-vis spectroscopy, elemental analyses
Karla I. Garfias-Gonzalez +6 more
doaj +1 more source
Hydrogel‐Based Smart Materials for Wound Healing and Sensing
Aggregate, EarlyView.The graphical abstract illustrates the role of hydrogel‐based flexible materials in advancing biomedical applications, including wound healing, point‐of‐care diagnostics, smart patches, and wearable devices. Hydrogels are particularly promising in modern wound care due to their high‐water content, flexibility, and biocompatibility.
Thi Kim Ngan Duong +11 more
wiley +1 more source
Framework nucleic acids directed assembly of Au nanostructures for biomedical applications
Interdisciplinary Medicine, Volume 1, Issue 1, January 2023., 2023 This Review article discusses the advanced progress in the Au and DNA nanomaterials. Introduced by the latest advances in frame nucleic acids‐detected Au nanostructures, the biomedical applications including biosensing and therapeutics are explored.
Bing Liu, Zhonglin Qi, Jie Chao
wiley +1 more source
Dendrimers in anticancer drug delivery: mechanism of interaction of drug and dendrimers
Artificial Cells Nanomedicine and Biotechnology, 2016 Dendrimers represents a novel class of macromolecules, which are derived from branches upon branches type structural design. Dendrimers are emerging as promising drug-delivery molecule because of their extraordinary properties including membrane ...
Jaspreet Singh +4 more
semanticscholar +1 more source
Journal of the American Chemical Society, 2016 The modular synthesis of a library containing seven self-assembling amphiphilic Janus dendrimers is reported. Three of these molecules contain environmentally friendly chiral-racemic fluorinated dendrons in their hydrophobic part (RF), one contains ...
Qi Xiao +13 more
semanticscholar +1 more source
Angewandte Chemie International Edition, Accepted Article.Human H ferritin (HuHf) has excellent potential as a nanocarrier for the selective delivery of anticancer metal‐based drugs to tumour cells. Here, we addressed the interaction of the gold monocarbene compound Au(NHC)Cl with HuHf by electrospray ionization‐mass spectrometry (ESI‐MS) measurements, which provide the metalation state of the protein ...
Lucrezia Cosottini +9 more
wiley +1 more source
Macromolecular Bioscience, Volume 22, Issue 12, December 2022., 2022 The combination of solid phase polymer synthesis and enzymatic sialyation is used to yield multivalent stereoselective 3′‐sialyllactose‐presenting macromolecules. The one pot reaction using synthetase NmCSS and sialyltransferase PmST1 is suitable to transfer sialic acid to either glycan acceptors, such as lactose, but as shown now in this study also to
Patrick B. Konietzny +6 more
wiley +1 more source
International Journal of Molecular Sciences, 2017 Drug delivery into the central nervous system (CNS) is challenging due to the blood–brain barrier (BBB) and drug delivery into the brain overcoming the BBB can be achieved using nanoparticles such as dendrimers.
B. Srinageshwar +17 more
semanticscholar +1 more source
Controlled Growth of Oligophenylene‐Structures on Graphene for Facile Secondary functionalization.
Angewandte Chemie International Edition, Accepted Article.Functionalization of graphene derivatives is a common approach to tune material properties for use in various applications. Due to the low reactivity of the unsaturated carbon lattice of graphene, not only are few chemical approaches suitable for successful functionalization, such as those involving highly reactive in situ formed radical species or ...
Christian Eberhard Halbig +6 more
wiley +1 more source