Results 31 to 40 of about 43,848 (310)

Click Chemistry of Melamine Dendrimers: Comparison of “Click-and-Grow” and “Grow-Then-Click” Strategies Using a Divergent Route to Diversity

open access: yesMolecules, 2022
Dendrimers are attractive macromolecules for a broad range of applications owing to their well-defined shapes and dimensions, highly branched and globular architectures, and opportunities for exploiting multivalency.
Sanami Numai   +4 more
doaj   +1 more source

Structure of DNA-Functionalized Dendrimer Nanoparticles [PDF]

open access: yesSoft Matter, 2012, 8, 1893-1900, 2012
Atomistic molecular dynamics simulations have been carried out to reveal the characteristic features of ethylenediamine (EDA) cored protonated poly amido amine (PAMAM) dendrimers of generation 3 (G3) and 4 (G4) that are functionalized with single stranded DNAs (ssDNAs).
arxiv   +1 more source

Dendrimer-protein interactions versus dendrimer-based nanomedicine [PDF]

open access: yesColloids and Surfaces B: Biointerfaces, 2017
Dendrimers are hyperbranched polymers belonging to the huge class of nanomedical devices. Their wide application in biology and medicine requires understanding of the fundamental mechanisms of their interactions with biological systems. Summarizing, electrostatic force plays the predominant role in dendrimer-protein interactions, especially with ...
Shcharbin, Dzmitry   +10 more
openaire   +3 more sources

Mesoporous Silica Nanoparticles Decorated with Polycationic Dendrimers for Infection Treatment [PDF]

open access: yesActa Biomaterialia. 68, 261-271 (2018), 2021
This work aims to provide an effective and novel solution for the treatment of infection by using nanovehicles loaded with antibiotics capable of penetrating the bacterial wall, thus increasing the antimicrobial effectiveness. These nanosystems, named "nanoantibiotics", are composed of mesoporous silica nanoparticles (MSNs), which act as nanocarriers ...
arxiv   +1 more source

Self-Assembling Supramolecular Dendrimers for Biomedical Applications: Lessons Learned from Poly(amidoamine) Dendrimers.

open access: yesAccounts of Chemical Research, 2020
ConspectusDendrimers, notable for their well-defined radial structures with numerous terminal functionalities, hold great promise for biomedical applications such as drug delivery, diagnostics, and therapeutics.
Zhenbin Lyu   +3 more
semanticscholar   +1 more source

Dendrimer Assisted Dispersion of Carbon Nanotubes: A Molecular Dynamics Study [PDF]

open access: yesSoft Matter, 2016,12, 8512-8520, 2016
Various unique physical, chemical, mechanical and electronic properties of carbon nanotube (CNT) make it very useful materials for diverse potential application in many fields. Experimentally synthesized CNTs are generally found in bundle geometry with a mixture of different chirality and present a unique challenge to separate them.
arxiv   +1 more source

Analysis of Biotinylated Generation 4 Poly(amidoamine) (PAMAM) Dendrimer Distribution in the Rat Brain and Toxicity in a Cellular Model of the Blood-Brain Barrier

open access: yesMolecules, 2013
Dendrimers are highly customizable nanopolymers with qualities that make them ideal for drug delivery. The high binding affinity of biotin/avidin provides a useful approach to fluorescently label synthesized dendrimer-conjugates in cells and tissues.
Heather A. Bullen   +10 more
doaj   +1 more source

Coupled exciton model with off-diagonal disorder for optical excitations in extended dendrimers [PDF]

open access: yesPhys. Chem. Chem. Phys. 1 (1999) 1687-1689, 1998
A phenomenological coupled exciton model is proposed in order to characterize optical excitations in extended dendrimers. An onsite exciton state is assigned at each phenyl rings and a nearest neighbor hopping integral which obeys the Gaussian distribution is considered between the exciton states.
arxiv   +1 more source

Extracellular Matrix Targeted MRI Probes

open access: yesAnalysis &Sensing, Volume 3, Issue 1, January 2023., 2023
Gadolinium based MRI probes targeted to ECM components, either proteins or enzymes, hold promise for accurate molecular characterization and staging of fibrotic diseases in vivo. Non‐covalent binding probes (1), reactive probes (2), and enzyme‐responsive probes (3) are discussed.
Giuseppe Digilio   +3 more
wiley   +1 more source

Nanoparticle Effects on Human Platelets in Vitro: A Comparison between PAMAM and Triazine Dendrimers

open access: yesMolecules, 2016
Triazine and PAMAM dendrimers of similar size and number of cationic surface groups were compared for their ability to promote platelet aggregation. Triazine dendrimers (G3, G5 and G7) varied in molecular weight from 8 kDa–130 kDa and in surface groups ...
Alan E. Enciso   +5 more
doaj   +1 more source

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