Results 51 to 60 of about 43,848 (310)
Structure of poly(propyl ether imine) (PETIM) dendrimer from fully atomistic molecular Dynamics Simulation and by Small Angle X-ray scattering [PDF]
JCP, 124, 204719 (2006), 2006 We study the structure of carboxylic acid terminated neutral poly (propyl ether imine) (PETIM) dendrimer from generation 1 through 6 (G1-G6) in a good solvent (water) by fully atomistic molecular dynamics (MD) simulations. We determine as a function of generation such structural properties as: radius of gyration, shape tensor, asphericity, fractal ...
arxiv +1 more source
Dendrimers for siRNA Delivery [PDF]
Pharmaceuticals, 2013 Since the discovery of the “starburst polymer”, later renamed as dendrimer, this class of polymers has gained considerable attention for numerous biomedical applications, due mainly to the unique characteristics of this macromolecule, including its monodispersity, uniformity, and the presence of numerous functionalizable terminal groups.
Swati Biswas, Vladimir P. Torchilin
openaire +4 more sources
Dendrimers as Antiamyloid Agents
Pharmaceutics, 2022 Dendrimer–protein conjugates have significant prospects for biological applications. The complexation changes the biophysical behavior of both proteins and dendrimers. The dendrimers could influence the secondary structure of proteins, zeta-potential, distribution of charged regions on the surface, the protein–protein interactions, etc.
Svetlana A. Sorokina +1 more
openaire +3 more sources
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 Abstract Objective This study sought to evaluate the feasibility of multifunctional gastrodin (GAS)‐containing nano‐drug carrier system against cerebral ischemia–reperfusion injury (CIRI). Methods The drug‐loaded nanocomposite (Au‐G5.NHAc‐PS/GAS) with certain encapsulation efficiency (EE) was prepared by physical adsorption method using different ...
Wenqiang Huang +8 more
wiley +1 more source
Nanotechnology as a New Therapeutic Approach to Prevent the HIV-Infection of Treg Cells. [PDF]
PLoS ONE, 2016 BACKGROUND:HIV-1 has proved to infect regulatory T cells (Treg) modifying their phenotype and impairing their suppressive capacity. As Treg cells are a crucial component in the preservation of the immune homeostasis, we researched that the antiviral ...
Didiana Jaramillo-Ruiz +4 more
doaj +1 more source
Trapping time statistics and efficiency of transport of optical excitations in dendrimers [PDF]
J. Chem. Phys. 121, 4884 (2004), 2004 We theoretically study the trapping time distribution and the efficiency of the excitation energy transport in dendritic systems. Trapping of excitations, created at the periphery of the dendrimer, on a trap located at its core, is used as a probe of the efficiency of the energy transport across the dendrimer.
arxiv +1 more source
Some New Aspects of Dendrimer Applications [PDF]
J. Lumin. 111, 315-325 (2005), 2004 Dendrimers are characterized by special features that make them promising candidates for many applications. Here we focus on two such applications: dendrimers as light harvesting antennae, and dendrimers as molecular amplifiers, which may serve as novel platforms for drug delivery. Both applications stem from the unique structure of dendrimers.
arxiv +1 more source
Strategies for the Preparation of Phosphorus Janus Dendrimers and Their Properties
Molecules, 2023 Dendrimers, being highly branched monodispersed macromolecules, predominantly exhibit identical terminal functionalities within their structural framework.
Joel Cejas-Sánchez +4 more
doaj +1 more source
Structure, phase behavior and inhomogeneous fluid properties of binary dendrimer mixtures [PDF]
J. Chem. Phys. 124 084901 (2006), 2005 The effective pair potentials between different kinds of dendrimers in solution can be well approximated by appropriate Gaussian functions. We find that in binary dendrimer mixtures the range and strength of the effective interactions depend strongly upon the specific dendrimer architecture.
arxiv +1 more source
Dendrimers in combination with natural products and analogues as anti-cancer agents.
Chemical Society Reviews, 2018 For the first time, an overview of dendrimers in combination with natural products and analogues as anti-cancer agents is presented. This reflects the development of drug delivery systems, such as dendrimers, to tackle cancers.
S. Mignani +6 more
semanticscholar +1 more source