Results 71 to 80 of about 43,848 (310)
Macromol, 2023 Dendrimers are increasingly being studied in the context of encapsulation. Many potential applications of dendrimers are based on their properties. They are used in drug delivery systems, cosmetics, food and chemistry.
Katia Bacha +4 more
doaj +1 more source
Molecular Dynamics Study of Charged Dendrimers in Salt-Free Solution: Effect of Counterions [PDF]
, 2005 Polyamidoamine (PAMAM) dendrimers, being protonated under physiological conditions, represent a promising class of nonviral, nano-sized vectors for drug and gene delivery. We performed extensive molecular dynamics simulations of a generic model dendrimer in a salt-free solution with dendrimer's terminal beads positively charged.
arxiv +1 more source
Coherent exciton transport in dendrimers and continuous-time quantum walks [PDF]
J. Chem. Phys. 124, 124905 (2006), 2006 We model coherent exciton transport in dendrimers by continuous-time quantum walks (CTQWs). For dendrimers up to the second generation the coherent transport shows perfect recurrences, when the initial excitation starts at the central node. For larger dendrimers, the recurrence ceases to be perfect, a fact which resembles results for discrete quantum ...
arxiv +1 more source
Dendrimers in gene delivery [PDF]
Advanced Drug Delivery Reviews, 2005 Dendrimers have unique molecular architectures and properties that make them attractive materials for the development of nanomedicines. Key properties such as defined architecture and a high ratio of multivalent surface moieties to molecular volume also make these nanoscaled materials highly interesting for the development of synthetic (non-viral ...
Dufès, Christine +2 more
openaire +4 more sources
Impact of Dendrimers on Solubility of Hydrophobic Drug Molecules
Frontiers in Pharmacology, 2017 Adequate aqueous solubility has been one of the desired properties while selecting drug molecules and other bio-actives for product development. Often solubility of a drug determines its pharmaceutical and therapeutic performance.
Sonam Choudhary +4 more
semanticscholar +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Dendrimer-based nanocomposites for the production of RNA delivery systems
OpenNano, 2023 A novel approach to treating cancer has been revealed to be effective cancer vaccination. It has also been demonstrated that nucleic acid therapies such as mRNA and siRNA are very efficient in the treatment of cancer.
Chiou Chyi Lim +2 more
doaj
Biological properties of water-soluble phosphorhydrazone dendrimers
Brazilian Journal of Pharmaceutical Sciences, 2013 Dendrimers are hyperbranched and perfectly defined macromolecules, constituted of branches emanating from a central core in an iterative fashion. Phosphorhydrazone dendrimers constitute a special family of dendrimers, possessing one phosphorus atom at ...
Anne-Marie Caminade +2 more
doaj +1 more source
Condensation transition in DNA-polyaminoamide dendrimer fibers studied using optical tweezers [PDF]
Phys. Rev. Lett. 96, 118301 (2006), 2006 When mixed together, DNA and polyaminoamide (PAMAM) dendrimers form fibers that condense into a compact structure. We use optical tweezers to pull condensed fibers and investigate the decondensation transition by measuring force-extension curves (FECs).
arxiv +1 more source
Pharmaceutics, 2018 We present here the development of multifunctional doxorubicin (DOX)-conjugated poly(amidoamine) (PAMAM) dendrimers as a unique platform for pH-responsive drug release and targeted chemotherapy of cancer cells.
Mengen Zhang +8 more
semanticscholar +1 more source