Results 91 to 100 of about 11,205,379 (410)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Plasmacytoid dendritic cells in dermatology, [PDF]

open access: yesAnais Brasileiros de Dermatologia
Plasmacytoid dendritic cells are part of the dendritic cells family and are a relevant link between innate and adaptive immunity. They are the most potent producers of type 1 interferon, generating antiviral response, stimulating macrophages and ...
Natasha Favoretto Dias de Oliveira   +3 more
doaj   +2 more sources

Interleukin-3Rα+ Myeloid Dendritic Cells and Mast Cells Develop Simultaneously from Different Bone Marrow Precursors in Cultures with Interleukin-3 [PDF]

open access: yes, 2003
The distinct developmental routes of dendritic cells and mast cells from murine bone marrow cultures with interleukin-3 are unclear. We found that short-term bone marrow cultures with interleukin-3 after 8–10 d consist of about 10%–30% dendritic cells ...
Baumeister, Thomas   +6 more
core   +1 more source

Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

open access: yesJournal of Experimental Medicine, 2007
To maintain immune homeostasis, the intestinal immune system has evolved redundant regulatory strategies. In this regard, the gut is home to a large number of regulatory T (T reg) cells, including the Foxp3+ T reg cell.
Cheng-Ming Sun   +7 more
semanticscholar   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity

open access: yesCell Reports, 2020
Summary: Human dendritic cells (DCs) comprise subsets with distinct phenotypic and functional characteristics, but the transcriptional programs that dictate their identity remain elusive.
Rebecca Leylek   +9 more
doaj  

Different Life Cycle Stages of Plasmodium falciparum Induce Contrasting Responses in Dendritic Cells

open access: yesFrontiers in Immunology, 2019
Dendritic cells are key linkers of innate and adaptive immunity. Efficient dendritic cell activation is central to the acquisition of immunity and the efficacy of vaccines.
Xi Zen Yap   +11 more
doaj   +1 more source

Spatial embedding of neuronal trees modeled by diffusive growth [PDF]

open access: yesarXiv, 2006
The relative importance of the intrinsic and extrinsic factors determining the variety of geometric shapes exhibited by dendritic trees remains unclear. This question was addressed by developing a model of the growth of dendritic trees based on diffusion-limited aggregation process.
arxiv  

Langerhans Cells as Macrophages in Skin and Lymhphoid Organs [PDF]

open access: yes, 1980
Properties of epidermal Langerhans cell were compared with those of a number of other dendritic cells in lymphoid organs and of mononuclear phagocytes. Among the dendritic “reticulum” cells included were indetenninate dendritic cells from the epidermis ...
Flotte, Thomas J.   +2 more
core   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

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