Results 271 to 280 of about 783,013 (308)
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Frontiers in Bioscience, 2007
Dendritic cells are antigen-presenting cells that have been shown to stimulate tumor antigen-specific T cell responses in preclinical studies. Consequently, there has been intense interest in developing dendritic cell based cancer vaccines. A variety of methods for generating dendritic cells, loading them with tumor antigens, and administering them to ...
Paul J, Mosca +4 more
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Dendritic cells are antigen-presenting cells that have been shown to stimulate tumor antigen-specific T cell responses in preclinical studies. Consequently, there has been intense interest in developing dendritic cell based cancer vaccines. A variety of methods for generating dendritic cells, loading them with tumor antigens, and administering them to ...
Paul J, Mosca +4 more
openaire +2 more sources
2012
Despite progress in brain tumor therapy, the prognosis of malignant glioma patients remains dismal. Among the new treatments currently being investigated, immunotherapy is theoretically very attractive since it offers the potential for high tumor-specific cytotoxicity.
Yamanaka, Ryuya, Kajiwara, Koji
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Despite progress in brain tumor therapy, the prognosis of malignant glioma patients remains dismal. Among the new treatments currently being investigated, immunotherapy is theoretically very attractive since it offers the potential for high tumor-specific cytotoxicity.
Yamanaka, Ryuya, Kajiwara, Koji
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Research in Immunology, 1989
Abundant evidence indicates that dendritic cells arise from the bone marrow. In vitro, precursors that differ phenotypically from mature dendritic cells divide several times to form functional dendritic cells. A soluble factor(s) produced in the supernatants of ConA-stimulated spleen cells enhances the production of dendritic cells.
W E, Bowers, E M, Goodell
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Abundant evidence indicates that dendritic cells arise from the bone marrow. In vitro, precursors that differ phenotypically from mature dendritic cells divide several times to form functional dendritic cells. A soluble factor(s) produced in the supernatants of ConA-stimulated spleen cells enhances the production of dendritic cells.
W E, Bowers, E M, Goodell
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2018
Generation of dendritic cells from both mouse and human tissues is a valuable technique for downstream immunotoxicological applications. Here, we describe methods for generation of four subsets of dendritic cells from murine bone marrow and three subsets of dendritic cells from human peripheral blood mononuclear cells.
Joanna M, Kreitinger, David M, Shepherd
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Generation of dendritic cells from both mouse and human tissues is a valuable technique for downstream immunotoxicological applications. Here, we describe methods for generation of four subsets of dendritic cells from murine bone marrow and three subsets of dendritic cells from human peripheral blood mononuclear cells.
Joanna M, Kreitinger, David M, Shepherd
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Seminars in Immunology, 2005
Cutaneous dendritic cells (DC) include epidermal Langerhans cells (LC), interstitial/dermal dendritic cells (DDC), as well as plasmacytoid DC (pDC) that occur under pathological conditions. These immune cells have a spectrum of different functions with implications that extend far beyond the skin.
Jenny, Valladeau, Sem, Saeland
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Cutaneous dendritic cells (DC) include epidermal Langerhans cells (LC), interstitial/dermal dendritic cells (DDC), as well as plasmacytoid DC (pDC) that occur under pathological conditions. These immune cells have a spectrum of different functions with implications that extend far beyond the skin.
Jenny, Valladeau, Sem, Saeland
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Dendritic Cells and Dendritic Cell Subsets
2016© 2016 Elsevier Ltd All rights reserved. Dendritic cells (DCs) are specialized antigen-presenting cells that may arise naturally from common DC progenitors in the bone marrow or develop from monocytes during inflammation. Migratory DCs arrive in lymph nodes (LNs) from the tissues, while LN-resident DCs are recruited from the blood.
Collin M, Haniffa M
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Immunology Today, 1997
Abstract T cells bearing receptors with high affinity for self-antigens are responsible for the generation of autoimmune diseases. Therefore, potentially autoreactive thymocytes must be eliminated or inactived in normal individuals. Induction of tolerance in thymocytes occurs by a process of negative selection controlled by the thymic stroma, and in ...
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Abstract T cells bearing receptors with high affinity for self-antigens are responsible for the generation of autoimmune diseases. Therefore, potentially autoreactive thymocytes must be eliminated or inactived in normal individuals. Induction of tolerance in thymocytes occurs by a process of negative selection controlled by the thymic stroma, and in ...
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2007
Dendritic cells (DCs) are crucial in regulating the immune response by bridging innate and adaptive immunity. DCs are constantly migrating from the blood to the lungs and from the lungs to the draining lymph nodes. How DCs populate the lung in the absence of inflammation and how they are recruited there during inflammation remain unclear.
Hammad, H (Hamida), Lambrecht, Bart
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Dendritic cells (DCs) are crucial in regulating the immune response by bridging innate and adaptive immunity. DCs are constantly migrating from the blood to the lungs and from the lungs to the draining lymph nodes. How DCs populate the lung in the absence of inflammation and how they are recruited there during inflammation remain unclear.
Hammad, H (Hamida), Lambrecht, Bart
openaire +3 more sources