Results 31 to 40 of about 58,744 (263)

Low-intensity transcranial ultrasound stimulation improves memory in vascular dementia by enhancing neuronal activity and promoting spine formation

NeuroImage
Memory is closely associated with neuronal activity and dendritic spine formation. Low-intensity transcranial ultrasound stimulation (TUS) improves the memory of individuals with vascular dementia (VD).
Jiamin Pei, Cong Zhang, Xiao Zhang, Zhe Zhao, Xiangjian Zhang, Yi Yuan   +5 more
doaj   +1 more source

Dendritic Spines in the Spinal Cord: Live Action Pain

Neuroscience Insights, 2020
Dendritic spines are microscopic protrusions on neurons that house the postsynaptic machinery necessary for neurotransmission between neurons. As such, dendritic spine structure is intimately linked with synaptic function.
Curtis A Benson, Marike L Reimer, Andrew M Tan   +2 more
doaj   +1 more source

Three-dimensional spatial modeling of spines along dendritic networks in human cortical pyramidal neurons. [PDF]

PLoS ONE, 2017
We modeled spine distribution along the dendritic networks of pyramidal neurons in both basal and apical dendrites. To do this, we applied network spatial analysis because spines can only lie on the dendritic shaft.
Laura Anton-Sanchez, Pedro Larrañaga, Ruth Benavides-Piccione, Isabel Fernaud-Espinosa, Javier DeFelipe, Concha Bielza   +5 more
doaj   +1 more source

Spinal cord motor neuron plasticity accompanies second‐degree burn injury and chronic pain

Physiological Reports, 2019
Burn injuries and associated complications present a major public health challenge. Many burn patients develop clinically intractable complications, including pain and other sensory disorders. Recent evidence has shown that dendritic spine neuropathology
Siraj Patwa, Curtis A. Benson, Lauren Dyer, Kai‐Lan Olson, Lakshmi Bangalore, Myriam Hill, Stephen G. Waxman, Andrew M. Tan   +7 more
doaj   +1 more source

Transient Deregulation of Canonical Wnt Signaling in Developing Pyramidal Neurons Leads to Dendritic Defects and Impaired Behavior

Cell Reports, 2019
Summary: During development, the precise implementation of molecular programs is a key determinant of proper dendritic development. Here, we demonstrate that canonical Wnt signaling is active in dendritic bundle-forming layer II pyramidal neurons of the ...
Beatrice Viale, Lin Song, Volodymyr Petrenko, Anne-Laure Wenger Combremont, Alessandro Contestabile, Riccardo Bocchi, Patrick Salmon, Alan Carleton, Lijia An, Laszlo Vutskits, Jozsef Zoltan Kiss   +10 more
doaj   +1 more source

EphA7 isoforms differentially regulate cortical dendrite development.

PLoS ONE, 2020
The shape of a neuron facilitates its functionality within neural circuits. Dendrites integrate incoming signals from axons, receiving excitatory input onto small protrusions called dendritic spines.
Carrie E Leonard, Maryna Baydyuk, Marissa A Stepler, Denver A Burton, Maria J Donoghue   +4 more
doaj   +1 more source

Structural plasticity of dendritic spines [PDF]

Current Opinion in Neurobiology, 2012
Dendritic spines are small mushroom-like protrusions arising from neurons where most excitatory synapses reside. Their peculiar shape suggests that spines can serve as an autonomous postsynaptic compartment that isolates chemical and electrical signaling.
Miquel, Bosch, Yasunori, Hayashi
openaire   +2 more sources

Dendritic spine density is increased on nucleus accumbens D2 neurons after chronic social defeat

Scientific Reports, 2020
Stress alters the structure and function of brain reward circuitry and is an important risk factor for developing depression. In the nucleus accumbens (NAc), structural and physiological plasticity of medium spiny neurons (MSNs) have been linked to ...
Megan E. Fox, Antonio Figueiredo, Miriam S. Menken, Mary Kay Lobo   +3 more
doaj   +1 more source

The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta, Augusto J. Mendes, Valentina Garibotto, Cecilia Boccalini, Aurelien Lathuiliere, Innocenzo Rainero, Elisa Rubino, Henrik Zetterberg, Nicholas J. Ashton, Federica Ribaldi, Giovanni B. Frisoni, for the Alzheimer's Disease Neuroimaging Initiative   +11 more
wiley   +1 more source

Analog Classification of Human Hand Gestures Exploiting Dendritic Integration With an Organic Artificial Soma

Advanced Functional Materials, EarlyView.
An organic neuromorphic architecture for the classification of human motor behavior is presented and validated. It performs somatic integration by linearly combining the activity from three muscles. An investigation of synaptic weights is presented and discussed in relationship with the classification performance.
Ilenia Sergi, Federico Rondelli, Francesco Torricelli, Federica Velluto, Anna De Salvo, Michele Di Lauro, Luciano Fadiga, Fabio Biscarini   +7 more
wiley   +1 more source