Results 41 to 50 of about 95,281 (299)
Dendritic Spines in the Spinal Cord: Live Action Pain
Neuroscience Insights, 2020 Dendritic spines are microscopic protrusions on neurons that house the postsynaptic machinery necessary for neurotransmission between neurons. As such, dendritic spine structure is intimately linked with synaptic function.
Curtis A Benson +2 more
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Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density. [PDF]
PLoS ONE, 2016 The group I metabotropic glutamate receptors (mGluR1a and mGluR5) are important modulators of neuronal structure and function. Although these receptors share common signaling pathways, they are capable of having distinct effects on cellular plasticity ...
Kellie S Gross +5 more
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A Dynamin-3 Spliced Variant Modulates the Actin/Cortactin-Dependent Morphogenesis of Dendritic Spines [PDF]
, 2005 Immature dendrites extend many actin-rich filopodial structures that can be replaced by synapse-containing dendritic spines as the neuron matures. The large GTPase dynamin-3 (Dyn3) is a component of the postsynapse in hippocampal neurons but its function
Chen, Jing +3 more
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Three-dimensional spatial modeling of spines along dendritic networks in human cortical pyramidal neurons. [PDF]
PLoS ONE, 2017 We modeled spine distribution along the dendritic networks of pyramidal neurons in both basal and apical dendrites. To do this, we applied network spatial analysis because spines can only lie on the dendritic shaft.
Laura Anton-Sanchez +5 more
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Lipid dynamics at dendritic spines [PDF]
Frontiers in Neuroanatomy, 2014 Dynamic changes in the structure and composition of the membrane protrusions forming dendritic spines underlie memory and learning processes. In recent years a great effort has been made to characterize in detail the protein machinery that controls spine plasticity.
Dotti, Carlos Gerardo +2 more
openaire +4 more sources
Cell Reports, 2019 Summary: During development, the precise implementation of molecular programs is a key determinant of proper dendritic development. Here, we demonstrate that canonical Wnt signaling is active in dendritic bundle-forming layer II pyramidal neurons of the ...
Beatrice Viale +10 more
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EphA7 isoforms differentially regulate cortical dendrite development.
PLoS ONE, 2020 The shape of a neuron facilitates its functionality within neural circuits. Dendrites integrate incoming signals from axons, receiving excitatory input onto small protrusions called dendritic spines.
Carrie E Leonard +4 more
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Pathology of Synapses and Dendritic Spines
Neural Plasticity, 2012 Peer ...
Shira Knafo +3 more
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Dopaminergic signaling in dendritic spines [PDF]
Biochemical Pharmacology, 2008 Dopamine regulates movement, motivation, reward, and learning and is implicated in numerous neuropsychiatric and neurological disorders. The action of dopamine is mediated by a family of seven-transmembrane G protein-coupled receptors encoded by at least five dopamine receptor genes (D1, D2, D3, D4, and D5), some of which are major molecular targets ...
Wei-Dong, Yao +2 more
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Spinal cord motor neuron plasticity accompanies second‐degree burn injury and chronic pain
Physiological Reports, 2019 Burn injuries and associated complications present a major public health challenge. Many burn patients develop clinically intractable complications, including pain and other sensory disorders. Recent evidence has shown that dendritic spine neuropathology
Siraj Patwa +7 more
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