Results 91 to 100 of about 43,830 (285)

Assessing protein distribution and dendritic spine morphology relationships using structured illumination microscopy in cultured neurons

open access: yesSTAR Protocols
Summary: Dendritic spines are protrusions on dendrites forming the postsynaptic aspect of excitatory connections within the brain. Spine morphology is associated with synaptic functional strength and the spatial regulation of protein nanodomains within ...
Kathryn J. Bjornson, Michael E. Cahill
doaj   +1 more source

RGMa and Neogenin control dendritic spine morphogenesis via WAVE Regulatory Complex-mediated actin remodeling [PDF]

open access: gold, 2023
Kai Sempert   +5 more
openalex   +1 more source

Lattice Structures for Bone Replacement: The Intersection of Bone Biomechanics, Lattice Design, and Additive Manufacturing

open access: yesAdvanced Materials Technologies, EarlyView.
This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias   +4 more
wiley   +1 more source

Remodeling dendritic spines for treatment of traumatic brain injury

open access: yesNeural Regeneration Research, 2019
Traumatic brain injury is an important global public health problem. Traumatic brain injury not only causes neural cell death, but also induces dendritic spine degeneration. Spared neurons from cell death in the injured brain may exhibit dendrite damage,
Ye Xiong, Asim Mahmood, Michael Chopp
doaj   +1 more source

Advances in Solid‐Phase Processing Techniques: Innovations, Applications, and Future Perspectives

open access: yesAdvanced Materials Technologies, EarlyView.
Based on practical manufacturing challenges, this review examines advanced solid‐phase processing techniques that overcome the inherent limitations of conventional melting‐based and traditional solid‐phase manufacturing, enabling the production of higher‐performance components at reduced cost through process innovation and improved supply‐chain ...
Tianhao Wang
wiley   +1 more source

Hydrogel‐Based Functional Materials: Classifications, Properties, and Applications

open access: yesAdvanced Materials Technologies, EarlyView.
Conductive hydrogels have emerged as promising materials for smart wearable devices due to their outstanding flexibility, multifunctionality, and biocompatibility. This review systematically summarizes recent progress in their design strategies, focusing on monomer systems and conductive components, and highlights key multifunctional properties such as
Zeyu Zhang, Zao Cheng, Patrizio Raffa
wiley   +1 more source

Advances in Safe, Flexible, and Stretchable Batteries for Wearable Applications

open access: yesAdvanced Materials Technologies, EarlyView.
Unlike previous reviews centered on component‐based deformability, this work highlights safety‐driven design strategies for flexible and stretchable batteries. By integrating material‐level engineering, geometry‐controlled structures, biocompatibility, and self‐protection mechanisms, it establishes a unified framework that connects mechanical ...
Hyewon Kang   +4 more
wiley   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

open access: yesAdvanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva   +28 more
wiley   +1 more source

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