Results 71 to 80 of about 71,138 (196)

Organic Cation Transporter 3 (OCT3) Is Localized to Intracellular and Surface Membranes in Select Glial and Neuronal Cells Within the Basolateral Amygdaloid Complex of Both Rats and Mice [PDF]

, 2016
Organic cation transporter 3 (OCT3) is a high-capacity, low-affinity transporter that mediates corticosterone-sensitive uptake of monoamines including norepinephrine, epinephrine, dopamine, histamine and serotonin. OCT3 is expressed widely throughout the
Chan, June, Gasser, Paul J, Hurley, Matthew M., Pickel, Virginia M.   +3 more
core   +2 more sources

AVNP2 protects against cognitive impairments induced by C6 glioma by suppressing tumour associated inflammation in rats [PDF]

, 2020
© 2020 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/).Glioblastoma is a kind of malignant tumour and originates from the central nervous system.
Bankier, Barkal, Barria, Benros, Braganhol, Campos-Pires, Chen, Cheong, Chicoine, Crossen, D'Alessandris, d'Isa, da Silva, Dalton, Del Sol-Fernandez, Ferrandon, Froklage, Gong, Graf, Graus, Guogang Ren, Hao, Hara, He, Heppner, Hilverda, Hwang, Jacob, Janelsins, Ji, Jin Gao, Junyang Li, Lang, Liang, Limin Wu, Liu, McFarland, Meicen Liu, Meng, Mineharu, Mostofa, Murata, Myung, Nagano, Nan, Nan, Noy, Oh, Ohgaki, Okada, Ostrom, Ovais, Park, Parrott, Platten, Quant, Reichel, Reid, Ren, Ren, Ren, Saalik, Shan, Sholl, Sim, Solanki, Sorensen, Sorra, Spacek, Stupp, Stupp, Tanaka, Thompson, Thorsson, Van Dyk, Vecht, Venkatesh, Walker, Walker Ii, Wan, Wang, Wang, Weitzner, Williams, Woodward, Wu, Wu, Yang, Yang, Yang, Yang, Yu, Yu Jiang, Yuen-Ki Cheong, Zhang, Zhu, Zhuo Yang, Zong, Zou   +98 more
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Organization of TNIK in dendritic spines [PDF]

Journal of Comparative Neurology, 2015
ABSTRACTTumor necrosis factor receptor‐associated factor 2 (TRAF2)‐ and noncatalytic region of tyrosine kinase (NCK)‐interacting kinase (TNIK) has been identified as an interactor in the psychiatric risk factor, Disrupted in Schizophrenia 1 (DISC1). As a step toward deciphering its function in the brain, we performed high‐resolution light and electron ...
Alain C, Burette, Kristen D, Phend, Susan, Burette, Qingcong, Lin, Musen, Liang, Gretchen, Foltz, Noël, Taylor, Qi, Wang, Nicholas J, Brandon, Brian, Bates, Michael D, Ehlers, Richard J, Weinberg   +11 more
openaire   +2 more sources

An interactive time series image analysis software for dendritic spines

Scientific Reports, 2022
Live fluorescence imaging has demonstrated the dynamic nature of dendritic spines, with changes in shape occurring both during development and in response to activity. The structure of a dendritic spine correlates with its functional efficacy.
Ali Özgür Argunşah, Ertunç Erdil, Muhammad Usman Ghani, Yazmín Ramiro-Cortés, Anna F. Hobbiss, Theofanis Karayannis, Müjdat Çetin, Inbal Israely, Devrim Ünay   +8 more
doaj   +1 more source

Autism-related KLHL17 and SYNPO act in concert to control activity-dependent dendritic spine enlargement and the spine apparatus.

PLoS Biology, 2023
Dendritic spines, the tiny and actin-rich protrusions emerging from dendrites, are the subcellular locations of excitatory synapses in the mammalian brain that control synaptic activity and plasticity.
Hsiao-Tang Hu, Yung-Jui Lin, Ueh-Ting Tim Wang, Sue-Ping Lee, Yae-Huei Liou, Bi-Chang Chen, Yi-Ping Hsueh   +6 more
doaj   +1 more source

Reading out a spatiotemporal population code by imaging neighbouring parallel fibre axons in vivo. [PDF]

, 2015
The spatiotemporal pattern of synaptic inputs to the dendritic tree is crucial for synaptic integration and plasticity. However, it is not known if input patterns driven by sensory stimuli are structured or random.
Häusser, M, Wilms, CD
core   +1 more source

Dendritic spine alterations in schizophrenia [PDF]

Neuroscience Letters, 2015
Schizophrenia is a chronic illness affecting approximately 0.5-1% of the world's population. The etiology of schizophrenia is complex, including multiple genes, and contributing environmental effects that adversely impact neurodevelopment. Nevertheless, a final common result, present in many subjects with schizophrenia, is impairment of pyramidal ...
Caitlin E, Moyer, Micah A, Shelton, Robert A, Sweet   +2 more
openaire   +2 more sources

Psychedelics Promote Structural and Functional Neural Plasticity. [PDF]

, 2018
Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of depression and related disorders. The ability to promote both structural and functional plasticity in the PFC has been hypothesized to underlie the fast ...
Barragan, Eden V, Burbach, Kyle F, Cameron, Lindsay P, Dennis, Megan Y, Duim, Whitney C, Gray, John A, Greb, Alexandra C, Ly, Calvin, McAllister, A Kimberley, Olson, David E, Ori-McKenney, Kassandra M, Paddy, Michael R, Soltanzadeh Zarandi, Sina, Sood, Alexander, Wilson, Paige C, Wong, Jonathan M   +15 more
core   +2 more sources

MARCKS for Maintenance in Dendritic Spines [PDF]

Neuron, 2005
Synapses in the brain must maintain a balance between learning-related plasticity and the stability necessary for reliable function. In this issue of Neuron, Calabrese and Halpain describe cell-transfection experiments implicating MARCKS, a protein that binds to both the cell surface and actin cytoskeleton, in the maintenance of dendritic spines.
openaire   +3 more sources

Automatic dendritic spine detection using multiscale dot enhancement filters and sift features [PDF]

, 2014
Statistical characterization of morphological changes of dendritic spines is becoming of crucial interest in the field of neurobiology. Automatic detection and segmentation of dendritic spines promises significant reductions on the time spent by the ...
Argunsah, Ali Ozgur, Argunşah, Ali Özgür, Cetin, Mujdat, Erdil, Ertunc, Erdil, Ertunç, Rada, Lavdie, Unay, Devrim, Çetin, Müjdat, Ünay, Devrim   +8 more
core   +1 more source