Results 51 to 60 of about 261,993 (301)

Structural Plasticity in Neuronal Networks [PDF]

open access: yes, 2007
Neuronal networks are established during development by the formation of connections (synapses) between neurons. Once formed, these synapses undergo experience-dependent modifications throughout the lifespan of the animal (synaptic plasticity ...
Mysore, Shreesh Pranesh
core   +1 more source

ASD-Associated De Novo Mutations in Five Actin Regulators Show Both Shared and Distinct Defects in Dendritic Spines and Inhibitory Synapses in Cultured Hippocampal Neurons

open access: yesFrontiers in Cellular Neuroscience, 2018
Many actin cytoskeleton-regulating proteins control dendritic spine morphology and density, which are cellular features often altered in autism spectrum disorder (ASD).
Iryna Hlushchenko   +7 more
doaj   +1 more source

Development of neurons in the ectostriatum of normal and monocularly deprived zebra finches: a quantitative Golgi study [PDF]

open access: yes, 1988
Herrmann K, Bischof H-J. Development of neurons in the ectostriatum of normal and monocularly deprived zebra finches: a quantitative Golgi study. The Journal of Comparative Neurology.
Herrmann, Kathrin   +3 more
core   +1 more source

SPIN90 phosphorylation modulates spine structure and synaptic function. [PDF]

open access: yesPLoS ONE, 2013
The correct rearrangement of postsynaptic components in dendritic spines is important for driving changes of spine structure and synaptic function. SPIN90 plays an essential role in many cellular processes including actin polymerization, endocytosis ...
In Ha Cho   +5 more
doaj   +1 more source

Synaptic activity and the formation and maintenance of neuronal circuits [PDF]

open access: yes, 2005
One of the most fundamental features of neurons is their polarized organization with two types of neurites extending from the cell body, axons and dendrites that are both functionally and morphologically distinct.
Roelandse, Martijn Johan Louis
core   +1 more source

Mechanisms of Ca2+/calmodulin-dependent kinase II activation in single dendritic spines

open access: yesNature Communications, 2019
Activation of Ca2+/calmodulin-dependent kinase II (CaMKII) in dendritic spines is a key step of long-term potentiation (LTP) induction, yet the exact biochemical steps of CaMKIIα activation in dendritic spines remained elusive. In this study, the authors
Jui-Yun Chang   +3 more
doaj   +1 more source

Structural plasticity of dendritic spines [PDF]

open access: yesCurrent Opinion in Neurobiology, 2012
Dendritic spines are small mushroom-like protrusions arising from neurons where most excitatory synapses reside. Their peculiar shape suggests that spines can serve as an autonomous postsynaptic compartment that isolates chemical and electrical signaling.
Miquel, Bosch, Yasunori, Hayashi
openaire   +2 more sources

Differentiation of dendrites and the analysis of spine- like structures on Lobula Plate Tangential Cells in Drosophila melanogaster [PDF]

open access: yes, 2007
The development of dendrites leads to the establishment of cell-type specific morphology of dendritic trees that eventually determines the way in which synaptic information is processed within the nervous system. The aim of this study was to investigate
Koper, Ewa
core   +1 more source

Actin capping protein regulates postsynaptic spine development through CPI-motif interactions

open access: yesFrontiers in Molecular Neuroscience, 2022
Dendritic spines are small actin-rich protrusions essential for the formation of functional circuits in the mammalian brain. During development, spines begin as dynamic filopodia-like protrusions that are then replaced by relatively stable spines ...
Kenneth R. Myers   +6 more
doaj   +1 more source

Generalized Dystonia With Cervical Predominance in a Patient With a De Novo TCF20 Variant

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT TCF20 has been implicated in developmental delay and intellectual disability, with dystonia reported less frequently. We describe a woman in her early twenties with childhood‐onset learning difficulties, progressive dysarthria, tremor, and generalized dystonia with marked cervical predominance, associated with a de novo TCF20 frameshift ...
Melisa Kilic   +7 more
wiley   +1 more source

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