Structural Plasticity in Neuronal Networks [PDF]
Neuronal networks are established during development by the formation of connections (synapses) between neurons. Once formed, these synapses undergo experience-dependent modifications throughout the lifespan of the animal (synaptic plasticity ...
Mysore, Shreesh Pranesh
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Many actin cytoskeleton-regulating proteins control dendritic spine morphology and density, which are cellular features often altered in autism spectrum disorder (ASD).
Iryna Hlushchenko +7 more
doaj +1 more source
Development of neurons in the ectostriatum of normal and monocularly deprived zebra finches: a quantitative Golgi study [PDF]
Herrmann K, Bischof H-J. Development of neurons in the ectostriatum of normal and monocularly deprived zebra finches: a quantitative Golgi study. The Journal of Comparative Neurology.
Herrmann, Kathrin +3 more
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SPIN90 phosphorylation modulates spine structure and synaptic function. [PDF]
The correct rearrangement of postsynaptic components in dendritic spines is important for driving changes of spine structure and synaptic function. SPIN90 plays an essential role in many cellular processes including actin polymerization, endocytosis ...
In Ha Cho +5 more
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Synaptic activity and the formation and maintenance of neuronal circuits [PDF]
One of the most fundamental features of neurons is their polarized organization with two types of neurites extending from the cell body, axons and dendrites that are both functionally and morphologically distinct.
Roelandse, Martijn Johan Louis
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Mechanisms of Ca2+/calmodulin-dependent kinase II activation in single dendritic spines
Activation of Ca2+/calmodulin-dependent kinase II (CaMKII) in dendritic spines is a key step of long-term potentiation (LTP) induction, yet the exact biochemical steps of CaMKIIα activation in dendritic spines remained elusive. In this study, the authors
Jui-Yun Chang +3 more
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Structural plasticity of dendritic spines [PDF]
Dendritic spines are small mushroom-like protrusions arising from neurons where most excitatory synapses reside. Their peculiar shape suggests that spines can serve as an autonomous postsynaptic compartment that isolates chemical and electrical signaling.
Miquel, Bosch, Yasunori, Hayashi
openaire +2 more sources
Differentiation of dendrites and the analysis of spine- like structures on Lobula Plate Tangential Cells in Drosophila melanogaster [PDF]
The development of dendrites leads to the establishment of cell-type specific morphology of dendritic trees that eventually determines the way in which synaptic information is processed within the nervous system. The aim of this study was to investigate
Koper, Ewa
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Actin capping protein regulates postsynaptic spine development through CPI-motif interactions
Dendritic spines are small actin-rich protrusions essential for the formation of functional circuits in the mammalian brain. During development, spines begin as dynamic filopodia-like protrusions that are then replaced by relatively stable spines ...
Kenneth R. Myers +6 more
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Generalized Dystonia With Cervical Predominance in a Patient With a De Novo TCF20 Variant
ABSTRACT TCF20 has been implicated in developmental delay and intellectual disability, with dystonia reported less frequently. We describe a woman in her early twenties with childhood‐onset learning difficulties, progressive dysarthria, tremor, and generalized dystonia with marked cervical predominance, associated with a de novo TCF20 frameshift ...
Melisa Kilic +7 more
wiley +1 more source

