Results 41 to 50 of about 71,138 (196)

Morphological analysis of dendrites and spines by hybridization of ridge detection with twin support vector machine [PDF]

open access: yesPeerJ, 2016
Dendritic spines are described as neuronal protrusions. The morphology of dendritic spines and dendrites has a strong relationship to its function, as well as playing an important role in understanding brain function.
Shuihua Wang   +6 more
doaj   +2 more sources

Image informatics strategies for deciphering neuronal network connectivity [PDF]

open access: yes, 2016
Brain function relies on an intricate network of highly dynamic neuronal connections that rewires dramatically under the impulse of various external cues and pathological conditions.
A Dani   +99 more
core   +2 more sources

Microtubules in Dendritic Spine Development [PDF]

open access: yesThe Journal of Neuroscience, 2008
It is generally believed that only the actin cytoskeleton resides in dendritic spines and controls spine morphology and plasticity. Here, we report that microtubules (MTs) are present in spines and that shRNA knockdown of the MT plus-end-binding protein EB3 significantly reduces spine formation.
Jiaping, Gu   +2 more
openaire   +2 more sources

NESH regulates dendritic spine morphology and synapse formation. [PDF]

open access: yesPLoS ONE, 2012
BackgroundDendritic spines are small membranous protrusions on the neuronal dendrites that receive synaptic input from axon terminals. Despite their importance for integrating the enormous information flow in the brain, the molecular mechanisms ...
Jeomil Bae   +4 more
doaj   +1 more source

The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

open access: yesNeural Regeneration Research, 2023
Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and memory. Kinesin-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with ...
Shi-Yan Sun   +7 more
doaj   +1 more source

Dendritic integration in olfactory bulb granule cells upon simultaneous multispine activation: Low thresholds for nonlocal spiking activity.

open access: yesPLoS Biology, 2020
The inhibitory axonless olfactory bulb granule cells form reciprocal dendrodendritic synapses with mitral and tufted cells via large spines, mediating recurrent and lateral inhibition.
Max Mueller, Veronica Egger
doaj   +1 more source

Nerve Conduction Through Dendrites via Proton Hopping [PDF]

open access: yes, 2017
Background: In our previous studies of nerve conduction conducted by proton hopping, we have considered the axon, soma, synapse and the nodes of Ranvier.
Kier, Lemont B.
core   +2 more sources

SPIN90 phosphorylation modulates spine structure and synaptic function. [PDF]

open access: yesPLoS ONE, 2013
The correct rearrangement of postsynaptic components in dendritic spines is important for driving changes of spine structure and synaptic function. SPIN90 plays an essential role in many cellular processes including actin polymerization, endocytosis ...
In Ha Cho   +5 more
doaj   +1 more source

Morphological plasticity of astroglia: Understanding synaptic microenvironment [PDF]

open access: yes, 2015
Memory formation in the brain is thought to rely on the remodeling of synaptic connections which eventually results in neural network rewiring. This remodeling is likely to involve ultrathin astroglial protrusions which often occur in the immediate ...
Heller, JP, Rusakov, DA
core   +1 more source

Lipid dynamics at dendritic spines [PDF]

open access: yesFrontiers in Neuroanatomy, 2014
Dynamic changes in the structure and composition of the membrane protrusions forming dendritic spines underlie memory and learning processes. In recent years a great effort has been made to characterize in detail the protein machinery that controls spine plasticity.
Dotti, Carlos Gerardo   +2 more
openaire   +4 more sources

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