C3 glomerulopathies: dense deposit disease and C3 glomerulonephritis [PDF]
Frontiers in Medicine, 2023 Dense deposit disease (DDD) and C3 glomerulonephritis (C3GN) are types of membranoproliferative glomerulonephritis classified as C3 glomerulopathies.
Claudio Ponticelli +4 more
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A long history of dense deposit disease [PDF]
BMC Ophthalmology, 2018 Background Dense Deposit Disease is a rare condition affecting the Bruch’s membrane and the glomerular basement membrane. We report the progression of the ocular manifestations over a 30 year follow up period, longer than any previous report.
Alan Cunningham, Ajay Kotagiri
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Blockade of Alternative Complement Pathway in Dense Deposit Disease [PDF]
Case Reports in Nephrology, 2014 A patient aged 17 with dense deposit disease associated with complement activation, circulating C3 Nef, and Factor H mutation presented with nephrotic syndrome and hypertension.
Aurore Berthe-Aucejo +6 more
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A Child with Dense Deposit Disease and Decreased Classic Complement Pathway Activity [PDF]
Acta Clinica Croatica, 2021 We report a rare case of nephritic syndrome underlying dense deposit disease (DDD) with alternative complement pathway dysfunction explained with both C3 nephritic factor (C3NeF) antibodies and DDD associated polymorphism of factor H. An 8-year-old boy
Ivana Trutin +4 more
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The Retinal Complications of C3 Dense Deposit Disease: A Scoping Review [PDF]
VisionPeople with C3 Dense Deposit Disease (C3DDD), a rare autoimmune disease, often also have ocular complications. Due to the rarity of this disease, there is little known about ocular complications in populations across the world. This paper aimed to assess
Jolene McCarney +4 more
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Iptacopan treatment for recurrent dense deposit disease after kidney transplant: A case report [PDF]
SAGE Open Medical Case ReportsC3 glomerulopathies, including dense deposit disease, are rare kidney disorders caused by dysregulation of the alternative complement pathway. Recurrence after kidney transplantation is common and can threaten graft survival.
Lean AlKhatib +3 more
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Case report: a rare concurrence of dense deposit disease in an adolescent patient with IgA nephropathy [PDF]
BMC PediatricsBackground Dense deposit disease (DDD) is a rare renal disorder major affecting adolescents and children, characterized by an absence of distinctive clinical symptoms.
Jian-Hui Zhang +6 more
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Favorable effect of bortezomib in dense deposit disease associated with monoclonal gammopathy: a case report [PDF]
BMC Nephrology, 2018 Background Complement component 3 (C3) glomerulopathy, which includes dense deposit disease (DDD) and C3 glomerulonephritis, is caused by dysregulation of the alternative complement pathway.
Shuma Hirashio +7 more
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A case of regression of atypical dense deposit disease without C3 deposition in a child [PDF]
Korean Journal of Pediatrics, 2010 Dense deposit disease (DDD) is a rare disorder characterized by the deposition of abnormal electron-dense material within the glomerular basement membrane of the kidneys. The diagnosis is made in most patients between 5 and 15 years of age, and within 10
Min Sun Kim +3 more
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Primary membranoproliferative glomerulonephritis: natural history, pathogenesis, and treatment [PDF]
Frontiers in NephrologyPrimary membranoproliferative glomerulonephritis (MPGN) is an ultrarare disease characterized by immunofluorescence microscopy as either immune-complex mediated (IC-MPGN) or C3 glomerulopathy (C3), the latter subdivided by electron microscopy to C3 ...
Edward J. Filippone, John L. Farber
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