Results 21 to 30 of about 16,816 (256)
Anti-factor B autoantibody in dense deposit disease [PDF]
Dense deposit disease (DDD), also known as membranoproliferative glomerulonephritis type II, is a rare kidney disorder that is associated with dysregulation of the alternative pathway of complement. Autoantibodies against the C3bBb convertase termed C3 nephritic factor are common in DDD patients.
Strobel, S. +4 more
openaire +4 more sources
Dense intramembranous deposit disease: New pathologic features
The pathologic and clinical features of 16 patients with dense intramembranous deposit disease are described. By light microscopy nine patients had membranoproliferative glomerulonephritis, five had focal segmental necrotizing glomerulonephritis with segmental epithelial crescents, four of whom also had a prominent tubulointerstitial nephritis, and two
Sibley, Richard K., Kim, Youngki
openaire +3 more sources
Dense deposit disease: A variant of membranoproliferative glomerulonephritis
It has been demonstrated in previous studies that there are several morphological variants of membranoproliferative glomerulonephritis (MPGN) [1–3]. In most cases mesangial cell proliferation and an increase in mesangial matrix are associated with capillary wall thickening (“classical MPGN”).
Habib, Renée +4 more
openaire +3 more sources
C3 glomerulopathy (C3G) is a rare disease resulting from dysregulation of the alternative pathway of complement. C3G includes C3 glomerulonephritis (C3GN) and dense deposit disease (DDD), both of which are characterized by bright glomerular C3 staining on immunofluorescence studies.
Raman Deep Singh +2 more
exaly +3 more sources
Treatment-resistant nephrotic syndrome in dense deposit disease: complement-mediated glomerular capillary wall injury? [PDF]
Contains fulltext : 225153.pdf (Publisher’s version ) (Open Access)BACKGROUND: The C3 glomerulopathies (C3G) are recently defined glomerular diseases, attributed to abnormal complement regulation.
Duineveld C +4 more
europepmc +2 more sources
Dense deposit disease complicated with choroidal neovascularization. [PDF]
Inanc M, Tekin K, Sekeroglu MA.
europepmc +4 more sources
Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease. [PDF]
Purpose: Dense deposit disease (DDD) is caused by dysregulation of the alternative pathway of the complement cascade and characterized by electron-dense deposits in the kidney glomerular basement membrane (GBM) and drusen in Bruch's membrane (BrM ...
Song D +9 more
europepmc +2 more sources
A new complement factor B mutation associated with crescentic C3 glomerulopathy; a case report [PDF]
Background: C3 glomerulopathy is a recently described entity classified as complementassociated glomerular disease. Case Presentation: We report a case of a 48-year-old man referred to the nephrology department for nephrotic syndrome with rapidly ...
Sofia Semedo Coelho +10 more
doaj +1 more source
Dense deposit disease in Korean children: a multicenter clinicopathologic study. [PDF]
The purpose of this study was to investigate the clinical, laboratory, and pathologic characteristics of dense deposit disease (DDD) in Korean children and to determine whether these characteristics differ between Korean and American children with DDD ...
Park SJ +10 more
europepmc +2 more sources

