Results 21 to 30 of about 16,816 (256)

Anti-factor B autoantibody in dense deposit disease [PDF]

open access: yesMolecular Immunology, 2010
Dense deposit disease (DDD), also known as membranoproliferative glomerulonephritis type II, is a rare kidney disorder that is associated with dysregulation of the alternative pathway of complement. Autoantibodies against the C3bBb convertase termed C3 nephritic factor are common in DDD patients.
Strobel, S.   +4 more
openaire   +4 more sources

Dense intramembranous deposit disease: New pathologic features

open access: yesKidney International, 1984
The pathologic and clinical features of 16 patients with dense intramembranous deposit disease are described. By light microscopy nine patients had membranoproliferative glomerulonephritis, five had focal segmental necrotizing glomerulonephritis with segmental epithelial crescents, four of whom also had a prominent tubulointerstitial nephritis, and two
Sibley, Richard K., Kim, Youngki
openaire   +3 more sources

Dense deposit disease: A variant of membranoproliferative glomerulonephritis

open access: yesKidney International, 1975
It has been demonstrated in previous studies that there are several morphological variants of membranoproliferative glomerulonephritis (MPGN) [1–3]. In most cases mesangial cell proliferation and an increase in mesangial matrix are associated with capillary wall thickening (“classical MPGN”).
Habib, Renée   +4 more
openaire   +3 more sources

Apolipoprotein E is enriched in dense deposits and is a marker for dense deposit disease in C3 glomerulopathy

open access: yesKidney International
C3 glomerulopathy (C3G) is a rare disease resulting from dysregulation of the alternative pathway of complement. C3G includes C3 glomerulonephritis (C3GN) and dense deposit disease (DDD), both of which are characterized by bright glomerular C3 staining on immunofluorescence studies.
Raman Deep Singh   +2 more
exaly   +3 more sources

Treatment-resistant nephrotic syndrome in dense deposit disease: complement-mediated glomerular capillary wall injury? [PDF]

open access: yesPediatr Nephrol, 2020
Contains fulltext : 225153.pdf (Publisher’s version ) (Open Access)BACKGROUND: The C3 glomerulopathies (C3G) are recently defined glomerular diseases, attributed to abnormal complement regulation.
Duineveld C   +4 more
europepmc   +2 more sources

Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease. [PDF]

open access: yesInvest Ophthalmol Vis Sci, 2018
Purpose: Dense deposit disease (DDD) is caused by dysregulation of the alternative pathway of the complement cascade and characterized by electron-dense deposits in the kidney glomerular basement membrane (GBM) and drusen in Bruch's membrane (BrM ...
Song D   +9 more
europepmc   +2 more sources

A new complement factor B mutation associated with crescentic C3 glomerulopathy; a case report [PDF]

open access: yesJournal of Nephropathology, 2019
Background: C3 glomerulopathy is a recently described entity classified as complementassociated glomerular disease. Case Presentation: We report a case of a 48-year-old man referred to the nephrology department for nephrotic syndrome with rapidly ...
Sofia Semedo Coelho   +10 more
doaj   +1 more source

Dense deposit disease in Korean children: a multicenter clinicopathologic study. [PDF]

open access: yesJ Korean Med Sci, 2012
The purpose of this study was to investigate the clinical, laboratory, and pathologic characteristics of dense deposit disease (DDD) in Korean children and to determine whether these characteristics differ between Korean and American children with DDD ...
Park SJ   +10 more
europepmc   +2 more sources

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