, 2007 Dense granules, a type of platelet secretory organelle, are known to accumulate high concentrations of small molecules such as calcium, adenine nucleotides, serotonin, pyrophosphate, and polyphosphate.
Aurelio Serrano (8667681) +8 more
core +4 more sources
Generation and analysis of mouse lines with a defect in platelet secretion and application in mouse models of atherosclerosis and tumor metastasis [PDF]
, 2013 Introduction: The involvement of platelets in various diseases has been increasingly recognized in the recent decades. This contribution is believed to involve platelet secretion and formation of reactive microparticles.
Schumacher, Dagmar
core
Chromogranin A, an “On/Off” Switch Controlling Dense-Core Secretory Granule Biogenesis
, 2001 We present evidence that regulation of dense-core secretory granule biogenesis and hormone secretion in endocrine cells is dependent on chromogranin A (CGA).
Tao-Cheng, Jung-Hwa +3 more
core +1 more source
npj Regenerative MedicineThe success of implanted tissue-engineered vascular grafts (TEVGs) relies on the coordinated inflammation and wound healing processes that simultaneously degrade the scaffold and guide the formation of a neovessel.
Mackenzie E. Turner +12 more
doaj +1 more source
Serotyping of Toxoplasma gondii Infection Using Peptide Membrane Arrays
Frontiers in Cellular and Infection Microbiology, 2019 The intracellular parasite Toxoplasma gondii can cause chronic infections in most warm-blooded animals, including humans. In the USA, strains belonging to four different Toxoplasma clonal lineages (types 1, 2, 3, and 12) are commonly isolated, whereas ...
David Arranz-Solís +7 more
doaj +1 more source
Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity. [PDF]
PLoS Genetics, 2016 Nonreplicating type I uracil auxotrophic mutants of Toxoplasma gondii possess a potent ability to activate therapeutic immunity to established solid tumors by reversing immune suppression in the tumor microenvironment.
Barbara A Fox +4 more
doaj +1 more source
207 Omega-3 and omega-6 fatty acids attenuate platelet reactivity in postmenopausal women
Journal of Clinical and Translational Science, 2022 OBJECTIVES/GOALS: This study aimed to investigate the mechanistic effects of fish oil (âμ-3 fatty acids) or evening primrose oil (âμ-6 fatty acids) supplementation on platelet reactivity in postmenopausal women.
Adriana Yamaguchi +6 more
doaj +1 more source
Functional and structural properties of dentate granule cells with hilar basal dendrites in mouse entorhino-hippocampal slice cultures [PDF]
, 2012 During postnatal development hippocampal dentate granule cells (GCs) often extend dendrites from the basal pole of their cell bodies into the hilar region. These so-called hilar basal dendrites (hBD) usually regress with maturation.
Gerlind Schuldt +26 more
core +1 more source
, 1998 Morphologically, the tachyzoites and the tissue cysts of Neospora caninum are difficult to distinguish from those of other cyst-forming apicomplexan parasites such as Toxoplasma gondii. Several stage-specific antigens have been identified in T.
Fuchs, N +3 more
core +1 more source
An Investigation of ABO Blood Type and the Platelet Delta Granule Storage Pool
Clinical and Applied Thrombosis/Hemostasis, 2021 Individuals with bleeding tendencies are more likely to have blood type O than blood types A, B, or AB. Platelet storage pool deficiencies are a lesser-known group of bleeding disorders which often go undiagnosed and may account for a significant number ...
Ryan J. Reagans +3 more
doaj +1 more source