Results 1 to 10 of about 100,674 (160)

Dentate Gyrus [PDF]

open access: yesNature Precedings, 2008
This report contains a gene expression summary of the dentate gyrus (DG), derived from the Allen Brain Atlas (ABA) _in situ_ hybridization mouse data set.
Allen Institute for Brain Science   +3 more
core   +3 more sources

Dentate gyrus is needed for memory retrieval. [PDF]

open access: yesMol Psychiatry
AbstractThe hippocampus is crucial for acquiring and retrieving episodic and contextual memories. In previous studies, the inactivation of dentate gyrus (DG) neurons by chemogenetic- and optogenetic-mediated hyperpolarization led to opposing conclusions about DG’s role in memory retrieval.
Carretero-Guillén A   +10 more
europepmc   +7 more sources

Enigmas of the Dentate Gyrus [PDF]

open access: yesNeuron, 2007
We are rapidly approaching a better understanding of the mechanisms that allow our brains to form distinct representations for similar events or episodes. McHugh et al. have brought that goal one step closer by showing that NMDA receptor-dependent synaptic plasticity in the dentate gyrus is necessary for immediate differentiation between environments ...
Edvard I. Moser, Jill K. Leutgeb
openaire   +3 more sources

Terminal differentiation of adult hippocampal progenitor cells is a step functionally dissociable from proliferation and is controlled by Tis21, Id3 and NeuroD2 [PDF]

open access: yes, 2017
Cell proliferation and differentiation are interdependent processes. Here, we have asked to what extent the two processes of neural progenitor cell amplification and differentiation are functionally separated.
Daniele Saraulli   +9 more
core   +2 more sources

The dentate gyrus: fundamental neuroanatomical organization (dentate gyrus for dummies) [PDF]

open access: yes, 2007
The dentate gyrus is a simple cortical region that is an integral portion of the larger functional brain system called the hippocampal formation. In this review, the fundamental neuroanatomical organization of the dentate gyrus is described, including principal cell types and their connectivity, and a summary of the major extrinsic inputs of the ...
Amaral David G   +2 more
openaire   +4 more sources

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults. [PDF]

open access: yes, 2018
New neurons continue to be generated in the subgranular zone of the dentate gyrus of the adult mammalian hippocampus. This process has been linked to learning and memory, stress and exercise, and is thought to be altered in neurological disease.
A Fahrner   +53 more
core   +1 more source

Functional and structural properties of dentate granule cells with hilar basal dendrites in mouse entorhino-hippocampal slice cultures [PDF]

open access: yes, 2012
During postnatal development hippocampal dentate granule cells (GCs) often extend dendrites from the basal pole of their cell bodies into the hilar region. These so-called hilar basal dendrites (hBD) usually regress with maturation.
Becker, Denise   +8 more
core   +6 more sources

The similarity of astrocytes number in dentate gyrus and CA3 subfield of rats hippocampus [PDF]

open access: yes, 2007
The dentate gyrus is a part of hippocampal formation that it contains granule cells, which project to the pyramidal cells and interneurons of the CA3 subfield of the hippocampus.
Hosseini, A.   +3 more
core   +1 more source

Effects of Imipramine and Lithium on the Suppression of Cell Proliferation in the Dentate Gyrus of the Hippocampus in Adrenocorticotropic Hormone-treated Rats [PDF]

open access: yes, 2010
We examined the influence of chronic adrenocorticotropic hormone (ACTH) treatment on the number of Ki-67-positive cells in the dentate gyrus of the hippocampus in rats. ACTH treatment for 14 days decreased the number of such cells.
Asanuma, Masato   +9 more
core   +1 more source

The dentate gyrus in depression

open access: yesEuropean Journal of Neuroscience, 2019
AbstractExtensive preclinical research has been conducted in recent years to reveal the cell types, neuronal circuits and molecular and morphological changes implicated in the function of the dentate gyrus in depression. This was profoundly facilitated by the emergence of methods such as gene targeting, neuronal cell activity manipulation, including ...
Gali Umschweif   +2 more
openaire   +4 more sources

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