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The enigmatic mossy cell of the dentate gyrus [PDF]
Nature Reviews Neuroscience, 2016 Mossy cells comprise a large fraction of the cells in the hippocampal dentate gyrus, suggesting that their function in this region is important. They are vulnerable to ischaemia, traumatic brain injury and seizures, and their loss could contribute to dentate gyrus dysfunction in such conditions.
Helen E Scharfman
exaly +5 more sources
Gamma rhythm communication between entorhinal cortex and dentate gyrus neuronal assemblies
Science, 2021 Brain region coordination in learning Gamma-frequency oscillations have been hypothesized as a physiological mechanism of interregional communication in the brain.
Antonio Fernández-Ruiz +2 more
exaly +2 more sources
Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus
Nature, 2018 Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by environmental influences, and functionally implicated in behavioural responses to stress and antidepressants1–4.
Christoph Anacker +2 more
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Nature Neuroscience, 2018 The dentate gyrus of the hippocampus is a brain region in which neurogenesis persists into adulthood; however, the relationship between developmental and adult dentate gyrus neurogenesis has not been examined in detail.
Hannah Hochgerner +2 more
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Evolution of the mammalian dentate gyrus [PDF]
Journal of Comparative Neurology, 2016 ABSTRACTThe dentate gyrus (DG), a part of the hippocampal formation, has important functions in learning, memory, and adult neurogenesis. Compared with homologous areas in sauropsids (birds and reptiles), the mammalian DG is larger and exhibits qualitatively different phenotypes: 1) folded (C‐ or V‐shaped) granule neuron layer, concave toward the hilus
R. Hevner
semanticscholar +4 more sources
F1000Research, 2018 Adult neurogenesis occurs in the dentate gyrus in the mammalian hippocampus. These new neurons arise from neural precursor cells named radial glia-like cells, which are situated in the subgranular zone of the dentate gyrus.
Daniel A. Berg +3 more
doaj +2 more sources
Nature Communications, 2018 Parvalbumin-positive (PV+) GABAergic interneurons in hippocampal microcircuits are thought to play a key role in several higher network functions, such as feedforward and feedback inhibition, network oscillations, and pattern separation.
Claudia Espinoza +2 more
exaly +2 more sources
Nature Communications, 2018 Early life experience influences stress reactivity and mental health through effects on cognitive-emotional functions that are, in part, linked to gene expression in the dorsal and ventral hippocampus.
Tie-Yuan Zhang +2 more
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Extended Interneuronal Network of the Dentate Gyrus. [PDF]
Cell Reports, 2017 Local interneurons control principal cells within individual brain areas, but anecdotal observations indicate that interneuronal axons sometimes extend beyond strict anatomical boundaries. Here, we use the case of the dentate gyrus (DG) to show that boundary-crossing interneurons with cell bodies in CA3 and CA1 constitute a numerically significant and ...
Gergely G. Szabo +5 more
semanticscholar +5 more sources
Dentate gyrus is needed for memory retrieval. [PDF]
Mol PsychiatryAbstractThe hippocampus is crucial for acquiring and retrieving episodic and contextual memories. In previous studies, the inactivation of dentate gyrus (DG) neurons by chemogenetic- and optogenetic-mediated hyperpolarization led to opposing conclusions about DG’s role in memory retrieval.
Carretero-Guillén A +10 more
europepmc +8 more sources