The effect of Urtica dioica extract on the number of astrocytes in the dentate gyrus of diabetic rats [PDF]
Diabetes mellitus is associated with cerebral alterations in both human and animal models of the disease. These alterations include abnormal expression of hypothalamic neuropeptides and hippocampal astrogliosis.
Afshar, M.+2 more
core
Remifentanil alleviates transient cerebral ischemia-induced memory impairment through suppression of apoptotic neuronal cell death in gerbils [PDF]
BackgroundDuring neurosurgical procedures, patients are often exposed to hypoxic and ischemic brain damage. Cerebral ischemia leads to neuronal cell death and eventually causes neurological impairments.
Sung-Wook Park+9 more
doaj +1 more source
Enhanced hippocampal long-term potentiation and spatial learning in aged 11ß-hydroxysteroid dehydrogenase type 1 knock-out mice [PDF]
Glucocorticoids are pivotal in the maintenance of memory and cognitive functions as well as other essential physiological processes including energy metabolism, stress responses, and cell proliferation.
Brownstein, D.+9 more
core +2 more sources
Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain
Abstract Background In mammals, specific brain regions such as the dentate gyrus (DG) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricles harbor adult neural stem/progenitor cells (ANSPCs) that give rise to new neurons and contribute to structural and functional brain plasticity.
Diana Zhilina+12 more
wiley +1 more source
Subfield-specific interneuron circuits govern the hippocampal response to novelty in male mice
The hippocampus is the brain’s center for episodic memories. Its subregions, the dentate gyrus and CA1-3, are differentially involved in memory encoding and recall. Hippocampal principal cells represent episodic features like movement, space, and context,
Thomas Hainmueller+3 more
doaj +1 more source
The granule cell density of the dentate gyrus following administration of Urtica dioica extract to young diabetic rats [PDF]
Urtica dioica L. Stinging nettle has long been known worldwide as a medicinal plant. To study the benefits of the nettle in diabetic encephalopathy, the granule cell density of the dentate gyrus of diabetic rats was studied following administration of ...
Fazeli, S.A.+4 more
core
Assessments of dentate gyrus function: discoveries and debates
M. Borzello+7 more
semanticscholar +1 more source
How informative are spatial CA3 representations established by the dentate gyrus? [PDF]
In the mammalian hippocampus, the dentate gyrus (DG) is characterized by sparse and powerful unidirectional projections to CA3 pyramidal cells, the so-called mossy fibers. Mossy fiber synapses appear to duplicate, in terms of the information they convey,
Cerasti, Erika, Treves, Alessandro
core +5 more sources
Usp9x-deficiency disrupts the morphological development of the postnatal hippocampal dentate gyrus
Within the adult mammalian brain, neurogenesis persists within two main discrete locations, the subventricular zone lining the lateral ventricles and the hippocampal dentate gyrus.
Sabrina Oishi+8 more
semanticscholar +1 more source
Summary: Physical activity is a strong positive physiological modulator of adult neurogenesis in the hippocampal dentate gyrus. Although the underlying regulatory mechanisms are still unknown, systemic processes must be involved.
Odette Leiter+9 more
doaj