Results 121 to 130 of about 131,553 (328)

The effect of spatial learning on the number of astrocytes in rat dentate gyrus [PDF]

open access: yes, 2007
In this study, we evaluated the effect of spatial learning on the number of astrocytes in the rat dentate gyrus with Morris water maze. Fifteen male albino Wistar rats were divided into three groups as control, reference memory and working memory groups.
Hosseini, A.   +3 more
core  

Role of hilar mossy cells in the CA3-dentate gyrus network during sharp wave-ripple activity in vitro [PDF]

open access: yes, 2019
Der Gyrus dentatus (DG) des Hippokampus wird als Eingangsstation für Informationen aus dem entorhinalen Kortex betrachtet. In das DG-Netzwerk sind zwei exzitatorische Zelltypen eingebettet: Körnerzellen, die Signale von dem entorhinalen Kortex empfangen,
Swaminathan, Aarti
core   +1 more source

Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAA Receptors Reduces Memory Interference

open access: yesJournal of Neuroscience, 2015
Interference between similar or overlapping memories formed at different times poses an important challenge on the hippocampal declarative memory system.
E. Engin   +8 more
semanticscholar   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

open access: yesEpilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Modulation of adult-born neurons in the inflamed hippocampus. [PDF]

open access: yes, 2013
Throughout life new neurons are continuously added to the hippocampal circuitry involved with spatial learning and memory. These new cells originate from neural precursors in the subgranular zone of the dentate gyrus, migrate into the granule cell layer,
Belarbi, Karim, Rosi, Susanna
core   +2 more sources

Mossy fiber sprouting in the dentate gyrus [PDF]

open access: yesEpilepsia, 2010
SummaryAberrant sprouting of granule cell axons is a common feature in temporal lobe epilepsy. An increasingly detailed picture of granule cell circuit changes has emerged, but the cause–effect relationship between mossy fiber sprouting and epileptogenesis remains unclear.
openaire   +2 more sources

Absence seizures: Update on signaling mechanisms and networks

open access: yesEpilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Dentate Gyrus Proliferative Responses After Traumatic Brain Injury and Binge Alcohol in Adult Rats

open access: yesNeuroscience Insights, 2020
Background: Traumatic brain injury is a significant public health issue that results in serious disability in survivors. Traumatic brain injury patients are often intoxicated with alcohol when admitted to the hospital; however, it is not clear how acute ...
Son T Ton   +8 more
doaj   +1 more source

Effects of chronic buproprion and nicotine administration on cell genesis and DNA fragmentation in adult rat dentate gyrus [PDF]

open access: yes, 2006
Previous experiments have shown that chronic subcutaneous administration of nicotine dose-dependently inhibits the acquisition and retention of a spatial task in the Morris water maze and reduces cell genesis in the dentate gyrus (DG) of adult rats.1 In ...
Scerri, Charles
core  

Perampanel as a second‐line therapy to midazolam reduces soman‐induced status epilepticus and neurodegeneration in rats

open access: yesEpilepsia Open, EarlyView.
Abstract Objective A benzodiazepine (diazepam or midazolam) is one of the current standards of care therapies to effectively terminate organophosphorus nerve agent‐induced status epilepticus when administered shortly after onset. Preclinical studies showed that benzodiazepines were less effective in stopping status epilepticus when treatment was ...
Hailey G. Steier   +8 more
wiley   +1 more source

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