Results 161 to 170 of about 131,553 (328)
Space, Time and Learning in the Hippocampus: How Fine Spatial and Temporal Scales Are Expanded into Population Codes for Behavioral Control [PDF]
, 2006 The hippocampus participates in multiple functions, including spatial navigation, adaptive timing, and declarative (notably, episodic) memory. How does it carry out these particular functions?
Gorchetchnikov, Anatoli +1 more
core +1 more source
Functional equivalence of stem cell and stem cell-derived extracellular vesicle transplantation to repair the irradiated brain. [PDF]
, 2020 Cranial radiotherapy, although beneficial for the treatment of brain tumors, inevitably leads to normal tissue damage that can induce unintended neurocognitive complications that are progressive and debilitating. Ionizing radiation exposure has also been
Acharya, Munjal M +13 more
core
Kappa opioids inhibit induction of long-term potentiation in the dentate gyrus of the guinea pig hippocampus [PDF]
, 1994 GW Terman +2 more
openalex +1 more source
Journal of Neuroscience, 2014 Previous studies suggest that spontaneous seizures in patients with temporal lobe epilepsy might be preceded by increased action potential firing of hippocampal neurons.
S. Fujita +3 more
semanticscholar +1 more source
Aging Cell, EarlyView.This study shows that human and mouse brains contain a different pool of strains that differentially affect the formation of Aβ and tau aggregates. Moreover, the murine seeds trigger an unresponsiveness microglial state, which causes the loss of plaque microglial coverage and affects the formation of amyloid plaques, leading to more severe neuritic ...
Juana Andreo‐Lopez +20 more
wiley +1 more source
Aging Cell, EarlyView.Here, we reanalyze single‐cell RNA sequencing datasets demonstrating hippocampal adult neural stem cell (NSC) heterogeneity to resolve classification inconsistencies and identify conserved gene markers. Our findings enhance understanding of NSC dynamics, aging, and senescence, providing a framework for standardized classification and improved insights ...
Oliver Polzer +4 more
wiley +1 more source
In vivo characterization of hippocampal electrophysiological processes in the heterozygous Pten knockout model of autism [PDF]
, 2018 While cognitive deficits have been described in the heterozygous Pten (+/-) KO mouse model of autism, little work has been done to demonstrate how corresponding in vitro physiological alterations in this model may underpin these cognitive deficits in ...
Barry, Jeremy +2 more
core +1 more source
Impaired long-term potentiation induction in dentate gyrus of calretinin-deficient mice [PDF]
, 1997 Stéphane Schurmans +9 more
openalex +1 more source
Aging Cell, EarlyView.Overexpression of GSK‐3β in DG GABAergic neurons impairs neurogenesis by reducing GABA release, which can be reversed by enhancing GABAergic transmission. ABSTRACT The activation of glycogen synthase kinase 3β (GSK‐3β) and the deterioration of spatial memory represent prominent pathological and clinical manifestations of Alzheimer's disease (AD ...
Fei Liu +11 more
wiley +1 more source
The ethanol metabolite acetaldehyde inhibits the induction of long‐term potentiation in the rat dentate gyrus in vivo [PDF]
, 1999 Kazuho Abe +3 more
openalex +1 more source