Recent optical approaches for anatomical and functional dissection of neuron–astrocyte circuitry
Abstract figure legend This review summarises novel optical approaches to deciphering structural and functional wiring diagrams of neuron–astrocyte circuits in the brain. There are three groups: the anatomical proximity assay, transsynaptic viral tracing and the functional connection assay. The FRET‐based neuron–astrocyte proximity assay allows mapping
Yoshiki Hatashita, Takafumi Inoue
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Differential Astrocyte-Supplied NMDAR Co-Agonist for CA1 Versus Dentate Gyrus Long-Term Potentiation. [PDF]
Sateesh S, Abraham WC.
europepmc +1 more source
Intermittent Fasting serves as a Potential Intervention to counteract the High Fat Diet induced Neuronal Changes in Dentate Gyrus of Rats [PDF]
Aya Abdelsattar Abdelfattah +3 more
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Abstract figure legend Experimentally induced status epilepticus induces microglial TNFα release, which binds to astrocytic TNFR1 and triggers activation of RIPK1/RIPK3/MLKL signalling, initiating necroptotic astrocytic death that contributes to the development of hippocampal sclerosis. Created with Biorender.com.
Zhou Wu +3 more
wiley +1 more source
Altered Neuroinflammatory Transcriptomic Profile in the Hippocampal Dentate Gyrus Three Weeks After Lateral Fluid Percussion Injury in Rats. [PDF]
DeSana AJ +6 more
europepmc +1 more source
Astrocytic Igfbp2 Promotes Spontaneous Seizures in a Mouse Model of Mesial Temporal Lobe Epilepsy
Igfbp2 is upregulated in hippocampal astrocytes of MTLE model mice. Igfbp2 enhances dentate granule cell excitability. Astrocytic Igfbp2 deletion reduces spontaneous seizures. ABSTRACT Mesial temporal lobe epilepsy (MTLE) is a common, frequently drug‐resistant epilepsy characterized by seizures arising from the hippocampus.
Shinichi Kinoshita +4 more
wiley +1 more source
Survey of transcriptome analyses of hippocampal neurogenesis with focus on adult dentate gyrus stem cells. [PDF]
Micheli L +5 more
europepmc +1 more source
Ectopic Expression of α6 and δ GABAAReceptor Subunits in Hilar Somatostatin Neurons Increases Tonic Inhibition and Alters Network Activity in the Dentate Gyrus [PDF]
Xiaoping Tong +7 more
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ATRX: From Chromatin Remodeling to Disease
ABSTRACT Chromatin remodeling proteins are evolutionarily conserved factors involved in a wide range of biological processes. In this review, we describe ATRX, a chromatin remodeling protein belonging to the SWI/SNF2 family. Its association with different protein complexes, and its roles in embryonic development, sexual differentiation, as well as ...
Mauro Magaña‐Acosta +1 more
wiley +1 more source

