Results 181 to 190 of about 117,269 (356)

Beyond diabetes and obesity: GLP‐1 receptor agonists in disrupting the vicious cycle of metabolic dysfunction and neuroinflammation

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Neurodegenerative diseases, including debilitating conditions like Alzheimer's and Parkinson's, are characterized by progressive neuronal loss, a process fundamentally driven by persistent chronic neuroinflammation and central metabolic dysfunction.
Renata Spezani   +1 more
wiley   +1 more source

Characterizing SUDEP dentate gyrus morphometry

open access: yes, 2021
My USRI project involved the characterization of dentate gyrus neuronal morphometry in SUDEP cases using the pathology software ...
openaire   +1 more source

Nanoparticle‐encapsulated neuropeptide Y provides robust seizure protection in SCN1A‐derived epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Neuropeptides have garnered great interest as potential treatments for epilepsy due to their impact on neuronal excitability through modulation of ion channels and neurotransmitter receptor activity. Neuropeptide Y (NPY) is a 36‐amino acid neuropeptide that is expressed primarily by γ‐aminobutyric acidergic (GABAergic) interneurons ...
Samantha L. Reed   +8 more
wiley   +1 more source

Effect of curcumin on hippocampus dentate gyrus injury induced by nicotine in rats [PDF]

open access: gold, 2019
Cyrus Jalili   +3 more
openalex   +1 more source

Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease

open access: yesEpilepsia, EarlyView.
Abstract Background and Objective Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B genes, characterized by the accumulation of Lafora bodies, drug‐resistant epilepsy, and cognitive decline. To investigate the early molecular mechanisms of LD, we studied electrophysiological changes in the dentate gyrus (DG ...
Cinzia Costa   +17 more
wiley   +1 more source

ACTIVATION OF DENTATE GYRUS ENGRAMS UNDER HIGH CONTEXTUAL AMBIGUITY LEADS TO REDUCED FEAR MEMORY RETRIEVAL [PDF]

open access: gold, 2023
Elif Gizem Kain   +3 more
openalex   +1 more source

Borna disease virus infection: Retrospective case series of five horses and two donkeys in Switzerland

open access: yesEquine Veterinary Education, EarlyView.
Summary Borna disease is an acute to subacute, rarely chronic non‐purulent meningoencephaylomyelitis affecting mainly horses and sheep. This case series describes the clinical signs, diagnosis, treatment, outcome and post‐mortem findings of five horses and two donkeys with this condition. The equids affected were geldings or mares of various breeds and
I. L. Piotrowski, M. Hilbe, H. K. Junge
wiley   +1 more source

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