Results 181 to 190 of about 131,553 (328)

Inhibition of long-term potentiation in the dentate gyrus of freely moving rats by the metabotropic glutamate receptor antagonist MCPG [PDF]

, 1995
Gernot Riedel, G. Casabona, KG Reymann
openalex   +1 more source

Immunity and neuroinflammation in early stages of life and epilepsy

Epilepsia, EarlyView.
Abstract The immune system is crucial for the correct brain development, and recent findings also point toward central control of immune response. As the immune system is not fully developed at birth, the early years become an important window for infections and for the development of epilepsy.
Angelica Vega García, María Leonor López‐Meraz, Marco I. González, Luisa Rocha, Jose Eduardo Peixoto‐Santos, Esper Abrão Cavalheiro   +5 more
wiley   +1 more source

Toward molecular phenotyping of temporal lobe epilepsy by spatial omics

Epilepsia, EarlyView.
Abstract Objective In temporal lobe epilepsy (TLE), detection of the epileptogenic zone predicts a good surgical outcome. When submitted to 18F‐fluorodeoxyglucose positron emission tomography (PET), some patients display lateralized, focal hypometabolism in the temporal lobe (PET+), whereas others appear normometabolic (PET−).
Isabeau Vermeulen, Ronny Mohren, Micca Neusinger, Tobias A. Dancker, Michiel Vandenbosch, Jan Beckervordersandforth, Benjamin Balluff, Rianna P. Van der Hel, Olaf E. M. G. Schijns, Govert Hoogland, Kim Rijkers, Berta Cillero‐Pastor, ACE epilepsy surgery group, Gwendolyn de Bruyn, Albert Colon, Jim Dings, Marc Hendriks, Danny Hilkman, Christianne Hoeberigs, Jochem van der Pol, Lotte de Jong, Kim Rijkers, Sylvia Klinkenberg, Vivianne van Kranen–Mastenbroek, Jeske Nelissen, Pieter Kubben, Walter M. Palm, Rob P. W. Rouhl, Olaf Schijns, Ilse van Straaten, Simon Tousseyn, Marielle Vlooswijk, Louis Wagner, Dorien Weckhuysen   +33 more
wiley   +1 more source

Lateral inhibition and granule cell synchrony in the rat hippocampal dentate gyrus [PDF]

, 1995
Sloviter Rs, JL Brisman
openalex   +1 more source

Patterns of phosphorylated tau accumulation in a spectrum of acquired and developmental brain lesions associated with refractory epilepsy

Epilepsia, EarlyView.
Abstract Objective Phosphorylated tau (pTau) has been reported in surgical resections in refractory epilepsy. It is unclear whether this is activity‐driven physiological pTau or signifies the advent of neurodegenerative cascades, relevant to memory decline.
Alicja Mrzyglod, Anya Mebrouk, Joanna Bartkiewicz, Hanaa El Hachami, Maritchka Ryniejska, Jane de Tisi, Roland Coras, Ingmar Blumcke, Fenglai Xiao, Anna Miserocchi, Andrew McEvoy, Matthias Koepp, Joan Liu, Maria Thom   +13 more
wiley   +1 more source

Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits. [PDF]

, 2017
The calcium-binding protein calbindin-D28k is critical for hippocampal function and cognition, but its expression is markedly decreased in various neurological disorders associated with epileptiform activity and seizures.
Chin, Jeannie, Corbett, Brian F., LaFrancois, John J., Mohila, Carrie A., Muralidharan, Kavitha, Nestler, Eric J., Park, Jin W., Petrof, Iraklis, Pyfer, Mark S., Rissman, Robert A., Scharfman, Helen E., Yoshor, Daniel, You, Jason C., Zhang, Xiaohong, Zheng, Yi   +14 more
core   +1 more source

Contribution of perineuronal nets to hyperexcitability in pilocarpine‐induced status epilepticus

Epilepsia, EarlyView.
Abstract Objective Changes in extracellular matrix (ECM) and highly condensed ECM structures called perineuronal nets (PNNs) have been reported in human patients with epilepsy as well as some animal models of epilepsy. We studied potential ECM changes in a mouse model of pilocarpine‐induced status epilepticus (PISE) and their potential contributions to
AnnaLin M. Woo, Erik J. Fleischel, Dipan C. Patel, Harald Sontheimer   +3 more
wiley   +1 more source

Exploring adult hippocampal neurogenesis using optogenetics [PDF]

, 2018
In the 1980s, it was widely accepted that new neurons are continuously generated in the dentate gyrus of the mammalian hippocampus. Since its acceptance, researchers have employed various techniques and behavioral paradigms to study the proliferation ...
Pinardo, Heinrich
core  

Unique Expression Patterns of Cell Fate Molecules Delineate Sequential Stages of Dentate Gyrus Development [PDF]

, 2000
Samuel J. Pleasure, Abigail E. Collins, Daniel H. Lowenstein   +2 more
openalex   +1 more source

Automatic detection of hippocampal sclerosis in patients with epilepsy

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to develop and validate an automatic, artificial intelligence‐enhanced software tool for hippocampal sclerosis (HS) detection, using a variety of standard magnetic resonance imaging (MRI) protocols from different MRI scanners for routine clinical practice.
Marcus Belke, Felix Zahnert, Mirja Steinbrenner, Mustafa Halimeh, Gadi Miron, Panagiota‐Eleni Tsalouchidou, Louise Linka, Boris Keil, Andreas Jansen, Vincent Möschl, André Kemmling, Christopher Nimsky, Felix Rosenow, Katja Menzler, Susanne Knake   +14 more
wiley   +1 more source