Results 11 to 20 of about 63,053 (291)

Enigmas of the Dentate Gyrus [PDF]

open access: yesNeuron, 2007
We are rapidly approaching a better understanding of the mechanisms that allow our brains to form distinct representations for similar events or episodes. McHugh et al. have brought that goal one step closer by showing that NMDA receptor-dependent synaptic plasticity in the dentate gyrus is necessary for immediate differentiation between environments ...
Edvard I. Moser, Jill K. Leutgeb
openaire   +3 more sources

The dentate gyrus: fundamental neuroanatomical organization (dentate gyrus for dummies) [PDF]

open access: yes, 2007
The dentate gyrus is a simple cortical region that is an integral portion of the larger functional brain system called the hippocampal formation. In this review, the fundamental neuroanatomical organization of the dentate gyrus is described, including principal cell types and their connectivity, and a summary of the major extrinsic inputs of the ...
Amaral David G   +2 more
openaire   +4 more sources

Transmembrane protein 108 involves in adult neurogenesis in the hippocampal dentate gyrus

open access: yesCell & Bioscience, 2019
Background Transmembrane protein 108 (Tmem108) is a risk gene of psychiatric diseases including schizophrenia, bipolar disorder and major depression disorder. However, the pathophysiological mechanisms of Tmem108 are largely unknown.
Zheng Yu   +8 more
doaj   +1 more source

Decrease in glucose transporter 1 levels and translocation of glucose transporter 3 in the dentate gyrus of C57BL/6 mice and gerbils with aging

open access: yesLaboratory Animal Research, 2018
In the present study, we compared the cell-specific expression and changes protein levels in the glucose transporters (GLUTs) 1 and 3, the major GLUTs in the mouse and gerbil brains using immuno-histochemistry and Western blot analysis. In both mouse and
Kwon Young Lee   +10 more
doaj   +1 more source

Terminal Differentiation of Adult Hippocampal Progenitor Cells Is a Step Functionally Dissociable from Proliferation and Is Controlled by Tis21, Id3 and NeuroD2

open access: yesFrontiers in Cellular Neuroscience, 2017
Cell proliferation and differentiation are interdependent processes. Here, we have asked to what extent the two processes of neural progenitor cell amplification and differentiation are functionally separated.
Laura Micheli   +9 more
doaj   +1 more source

Temporal changes in prosaposin expression in the rat dentate gyrus after birth. [PDF]

open access: yesPLoS ONE, 2014
Neurogenesis in the hippocampal dentate gyrus occurs constitutively throughout postnatal life. Adult neurogenesis includes a multistep process that ends with the formation of a postmitotic and functionally integrated new neuron. During adult neurogenesis,
Midori Morishita   +7 more
doaj   +1 more source

Dentate Gyrus

open access: yesNature Precedings, 2008
AbstractThis report contains a gene expression summary of the dentate gyrus (DG), derived from the Allen Brain Atlas (ABA) in situ hybridization mouse data set. The structure's location and morphological characteristics in the mouse brain are described using the Nissl data found in the Allen Reference Atlas.
Allen Institute for Brain Science   +3 more
openaire   +2 more sources

Combined role of seizure-induced dendritic morphology alterations and spine loss in newborn granule cells with mossy fiber sprouting on the hyperexcitability of a computer model of the dentate gyrus. [PDF]

open access: yesPLoS Computational Biology, 2014
Temporal lobe epilepsy strongly affects hippocampal dentate gyrus granule cells morphology. These cells exhibit seizure-induced anatomical alterations including mossy fiber sprouting, changes in the apical and basal dendritic tree and suffer substantial ...
Julian Tejada   +2 more
doaj   +1 more source

The dentate gyrus in depression

open access: yesEuropean Journal of Neuroscience, 2019
AbstractExtensive preclinical research has been conducted in recent years to reveal the cell types, neuronal circuits and molecular and morphological changes implicated in the function of the dentate gyrus in depression. This was profoundly facilitated by the emergence of methods such as gene targeting, neuronal cell activity manipulation, including ...
Gali Umschweif   +2 more
openaire   +4 more sources

Sampling the Mouse Hippocampal Dentate Gyrus [PDF]

open access: yesFrontiers in Neuroanatomy, 2017
ISSN:1662 ...
Lisa Basler   +7 more
openaire   +6 more sources

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