Results 191 to 200 of about 117,269 (356)

Dentate gyrus

, 2015
Henry Knipe, Jeremy Jones
openaire   +1 more source

D1/D5 receptor activation promotes long‐term potentiation and synaptic tagging/capture in hippocampal area CA2

The FEBS Journal, EarlyView.
Activation of dopamine receptor D1 (D1R) stimulates PKA and ERK pathways via dissociation of stimulatory and olfactory G protein alpha subunits (Gαs/olf). PKA relieves striatal‐enriched protein tyrosine phosphatase (STEP) inhibition of ERK, promoting cyclic adenosine monophosphate response element‐binding protein (CREB)‐driven transcription of ...
Kevin Chua, Yee Song Chong, Sreedharan Sajikumar   +2 more
wiley   +1 more source

Chronic silencing of subsets of cortical layer 5 pyramidal neurons has a long‐term influence on the laminar distribution of parvalbumin interneurons and the perineuronal nets

Journal of Anatomy, Volume 246, Issue 4, Page 479-504, April 2025.
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó, Veronika Sigutova, Anna M. Schneider, Anna Hoerder‐Suabedissen, Zoltán Molnár   +4 more
wiley   +1 more source

Adult neurogenesis modifies excitability of the dentate gyrus [PDF]

, 2013
Taruna Ikrar, Nannan Guo, Kaiwen He, B Antoine, Sally Levinson, Alexis S. Hill, Hey‐Kyoung Lee, René Hen, Xiangmin Xu, Amar Sahay   +9 more
openalex   +1 more source

Orchestrated molecular changes of proliferative, migratory‐fibrillar, synaptic, and postmigratory compartments align with precocious cortex‐type specification in the early human pallium

Journal of Anatomy, EarlyView.
Early human cortical development is organized by transient cellular compartments that define cortical types before mature layers form. Analysis of the human fetal pallium (7.5–15 PCW) shows distinct spatiotemporal trajectories for the archicortex, mesocortex, and neocortex, with delayed but accelerated differentiation in allocortical regions.
Janja Kopić, Fran Božić, Alisa Junaković Munjas, Željka Krsnik, Ivica Kostović   +4 more
wiley   +1 more source

Biphasic Change of Progenitor Proliferation in Dentate Gyrus After Single Dose of Isoflurane in Young Adult Rats

, 2013
Nan Lin, Tiffany S. Moon, Greg Stratmann, Jeffrey W. Sall   +3 more
openalex   +1 more source

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, EarlyView.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Transcriptome profiling of human hippocampus dentate gyrus granule cells in mental illness [PDF]

, 2014
R Kohen, Adrian Dobra, Julia Tracy, Eric Haugen   +3 more
openalex   +1 more source

Electrophysiological measurements of synaptic connectivity and plasticity in the longitudinal dentate gyrus network from mouse hippocampal slices

, 2023
Sarah Y. Kwon, Sojeong Pak, Sunggu Yang, Sungchil Yang   +3 more
openalex   +1 more source

Lateral septal nucleus, dorsal part, and dentate gyrus are necessary for spatial and object recognition memory, respectively, in mice [PDF]

, 2023
Ying-Ke Jiang, Fei-Yuan Dong, Yi-Bei Dong, Xinyi Zhu, Lu-Hui Pan, Linbo Hu, Le Xu, Xiao-Fan Xu, Limin Xu, Xiaoqin Zhang, Li-Min Xu, Xiao-Qin Zhang   +11 more
openalex   +1 more source