Results 191 to 200 of about 116,345 (333)

Hippocampal abnormality and response to vagus nerve stimulation in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Vagus nerve stimulation (VNS) reduces seizure frequency and severity in some, but not all, individuals with epilepsy. The hippocampus has been implicated in VNS response, but is yet to be studied structurally using T1‐weighted (T1w) magnetic resonance imaging (MRI).
Harry J. Clifford   +11 more
wiley   +1 more source

Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease

open access: yesEpilepsia, EarlyView.
Abstract Background and Objective Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B genes, characterized by the accumulation of Lafora bodies, drug‐resistant epilepsy, and cognitive decline. To investigate the early molecular mechanisms of LD, we studied electrophysiological changes in the dentate gyrus (DG ...
Cinzia Costa   +17 more
wiley   +1 more source

Borna disease virus infection: Retrospective case series of five horses and two donkeys in Switzerland

open access: yesEquine Veterinary Education, EarlyView.
Summary Borna disease is an acute to subacute, rarely chronic non‐purulent meningoencephaylomyelitis affecting mainly horses and sheep. This case series describes the clinical signs, diagnosis, treatment, outcome and post‐mortem findings of five horses and two donkeys with this condition. The equids affected were geldings or mares of various breeds and
I. L. Piotrowski, M. Hilbe, H. K. Junge
wiley   +1 more source

Postnatal development of the dentate gyrus vascular niche. [PDF]

open access: yesSci Rep
Devasthali N   +3 more
europepmc   +1 more source

D1/D5 receptor activation promotes long‐term potentiation and synaptic tagging/capture in hippocampal area CA2

open access: yesThe FEBS Journal, EarlyView.
Activation of dopamine receptor D1 (D1R) stimulates PKA and ERK pathways via dissociation of stimulatory and olfactory G protein alpha subunits (Gαs/olf). PKA relieves striatal‐enriched protein tyrosine phosphatase (STEP) inhibition of ERK, promoting cyclic adenosine monophosphate response element‐binding protein (CREB)‐driven transcription of ...
Kevin Chua   +2 more
wiley   +1 more source

Expression of c‐fos in hilar mossy cells of the dentate gyrus in vivo

open access: green, 2013
Áine Duffy   +3 more
openalex   +2 more sources

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