Results 211 to 220 of about 139,984 (307)

PTEN deletion in the adult dentate gyrus induces epilepsy. [PDF]

Neurobiol Dis
Yonan JM, Chen KD, Baram TZ, Steward O.
europepmc   +1 more source

Reduced tonic inhibition in the dentate gyrus contributes to chronic stress‐induced impairments in learning and memory

Hippocampus, 2016
Vallent Lee, Georgina MacKenzie, A. Hooper, J. Maguire   +3 more
semanticscholar   +1 more source

NADPH Oxidase Inhibition Promotes Brain Resilience by Attenuating Tauopathy and Neuroinflammation in Alzheimer's Disease

Advanced Science, Volume 12, Issue 42, November 13, 2025.
CRB‐2131, as a novel Nox inhibitor, suppresses brain oxidation, tauopathy, and neuro‐inflammation, thereby preventing death of mature neurons and promoting regeneration of immature neurons. Ultimately, this fosters a resilient brain and protects cognition.
Jihyeon Lee, Seunghwan Sim, Yinglan Jin, Hyejun Park, Eun Young Byeon, Su Jin Kim, Sujin Yun, Hye Eun Lee, Da Un Jeong, Jung Min Suh, In Hye Lee, Ho‐Young Lee, Yongseok Choi, Yun Soo Bae   +13 more
wiley   +1 more source

Protocol for culturing neurospheres from progenitor cells in the dentate gyrus of aged mouse hippocampus. [PDF]

STAR Protoc
Vafaeva O, Namchaiw P, Murray K, Diaz E, Cheng HJ.   +4 more
europepmc   +1 more source

Development of phasic and tonic inhibitory GABAergic currents in mouse dentate gyrus [PDF]

, 2009
Nadine I. Holter
openalex   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

Advanced Science, Volume 12, Issue 42, November 13, 2025.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao, Jing Wang, Bei Chen, Jinhui Yang, Fangyu Wu, Chunyao Zhou, Yifei Zhang, Zhiquan Yang, Dingyang Liu, Lei Tian, Jianhua Yu, Fei Han, Yongxiang Tang, Li Feng, Shuo Hu   +14 more
wiley   +1 more source

Cellular and circuit features distinguish mouse dentate gyrus semilunar granule cells and granule cells activated during contextual memory formation. [PDF]

Elife
Dovek L, Ahmadi M, Marrero K, Zagha E, Santhakumar V.   +4 more
europepmc   +1 more source

Vardenafil Increases Cell Proliferation in the Dentate Gyrus through Enhancement of Serotonin Expression in the Rat Dorsal Raphe [PDF]

, 2009
Tae Soo Kim, Il‐Gyu Ko, Yun-Hee Sung, Sung‐Eun Kim, Bo-Kyun Kim, Seung-Kook Park, Mal‐Soon Shin, Chang‐Ju Kim, Sang-Jin Yoon, Khae Hawn Kim   +9 more
openalex   +1 more source

Neurophilic Biomimetic Lipoprotein‐Mediated Targeted Nerve Growth Factor Delivery for Traumatic Brain Injury Therapy

Advanced Science, Volume 12, Issue 42, November 13, 2025.
Design of neurophilic biomimetic lipoprotein for intracerebral delivery of nerve growth factor (NGF) to traumatic brain injury (TBI). Nc‐rHDL@P can cross the BBB through ApoE3‐receptors interaction and target neurons via αRDP‐nAChR interaction. Nc‐rHDL@P delivers NGF to the lesion sites, rescues neurons, curbs inflammation, boosts sensorimotor and ...
Jialin Huang, Wenye Wang, Yidong Peng, Weiji Weng, Hanyu Wei, Qiyuan Feng, Antian Wang, Minjie Hu, Zhuoran Li, Shenyu Sun, Zhenghui He, Daiwen Zhang, Wenlan Qi, Yuhan Han, Zixuan Ma, Jiyuan Hui, Ru Gong, Yingwei Gao, Yong Lin, Jiyao Jiang, Xiaoling Gao, Junfeng Feng   +21 more
wiley   +1 more source

Dentate gyrus granule cell activation following extracellular electrical stimulation: a multi-scale computational model to guide hippocampal neurostimulation strategies. [PDF]

Front Comput Neurosci
Farzad S, Wei T, Bouteiller JC, Lazzi G.
europepmc   +1 more source