Results 21 to 30 of about 61,176 (239)

The Mechanism of Rate Remapping in the Dentate Gyrus [PDF]

Neuron, 2010
Rate remapping is a recently revealed neural code in which sensory information modulates the firing rate of hippocampal place cells. The mechanism underlying rate remapping is unknown. Its characteristic modulation, however, must arise from the interaction of the two major inputs to the hippocampus, the medial entorhinal cortex (MEC), in which grid ...
César Rennó-Costa, Paul F. M. J. Verschure, Paul F. M. J. Verschure, John E. Lisman   +3 more
openaire   +3 more sources

Pemberian Asam Valproat pada Induk Tikus Bunting Menghambat Sintesis Insulin pada Sel Otak Anak Tikus

Majalah Kedokteran Bandung, 2017
Asam valproat memengaruhi aktivitas histone deacetylase yang berperan dalam ekspresi gen selama organogenesis. Insulin berperan dalam proliferasi dan diferensiasi sel-sel saraf dentate gyrus hipokampus.
Komariah Komariah, Bambang Kiranadi, Adi Winanto, Wasmen Manalu, Ekowati Handharyani   +4 more
doaj   +1 more source

Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus

Laboratory Animal Research, 2018
Bacopa monnieri is a medicinal plant with a long history of use in Ayurveda, especially in the treatment of poor memory and cognitive deficits. In the present study, we hypothesized that Bacopa monnieri extract (BME) can improve memory via increased cell
Hyun Jung Kwon, Hyo Young Jung, Kyu Ri Hahn, Woosuk Kim, Jong Whi Kim, Dae Young Yoo, Yeo Sung Yoon, In Koo Hwang, Dae Won Kim   +8 more
doaj   +1 more source

Combined role of seizure-induced dendritic morphology alterations and spine loss in newborn granule cells with mossy fiber sprouting on the hyperexcitability of a computer model of the dentate gyrus. [PDF]

PLoS Computational Biology, 2014
Temporal lobe epilepsy strongly affects hippocampal dentate gyrus granule cells morphology. These cells exhibit seizure-induced anatomical alterations including mossy fiber sprouting, changes in the apical and basal dendritic tree and suffer substantial ...
Julian Tejada, Norberto Garcia-Cairasco, Antonio C Roque   +2 more
doaj   +1 more source

Microelastic mapping of the rat dentate gyrus [PDF]

Royal Society Open Science, 2016
The lineage commitment of many cultured stem cells, including adult neural stem cells (NSCs), is strongly sensitive to the stiffness of the underlying extracellular matrix. However, it remains unclear how well the stiffness ranges explored in culture align with the microscale stiffness values stem cells actually encounter within their ...
Tomás Luque, Michael S. Kang, David V. Schaffer, Sanjay Kumar   +3 more
openaire   +3 more sources

Postnatal and Adult Neurogenesis in Mammals, Including Marsupials

Cells, 2022
In mammals, neurogenesis occurs during both embryonic and postnatal development. In eutherians, most brain structures develop embryonically; conversely, in marsupials, a number of brain structures develop after birth.
Katarzyna Bartkowska, Beata Tepper, Krzysztof Turlejski, Ruzanna Djavadian   +3 more
doaj   +1 more source

Sex steroids and the dentate gyrus [PDF]

, 2007
In the late 1980s, the finding that the dentate gyrus contains more granule cells in the male than in the female of certain mouse strains provided the first indication that the dentate gyrus is a significant target for the effects of sex steroids during development. Gonadal hormones also play a crucial role in shaping the function and morphology of the
Teresa A. Milner, Teresa A. Milner, Tibor Hajszan, Csaba Leranth   +3 more
openaire   +2 more sources

Dentate gyrus volume deficit in schizophrenia [PDF]

Psychological Medicine, 2019
AbstractBackgroundSchizophrenia is associated with robust hippocampal volume deficits but subregion volume deficits, their associations with cognition, and contributing genes remain to be determined.MethodsHippocampal formation (HF) subregion volumes were obtained using FreeSurfer 6.0 from individuals with schizophrenia (n= 176, mean age ±s.d.= 39.0 ...
Soichiro Nakahara, Jessica A. Turner, Vince D. Calhoun, Kelvin O. Lim, Bryon Mueller, Juan R. Bustillo, Daniel S. O'Leary, Sarah McEwen, James Voyvodic, Aysenil Belger, Daniel H. Mathalon, Judith M. Ford, Fabio Macciardi, Mitsuyuki Matsumoto, Steven G. Potkin, Theo G. M. van Erp   +15 more
openaire   +4 more sources

Effect of Adult Neurogenesis on Sparsely Synchronized Rhythms of The Granule Cells in The Hippocampal Dentate Gyrus [PDF]

arXiv, 2023
We are concerned about the main encoding granule cells (GCs) in the hippocampal dentate gyrus (DG). Young immature GCs (imGCs) appear through adult neurogenesis. In comparison to the mature GCs (mGCs) (born during development), the imGCs show high activation due to lower firing threshold.
arxiv  

Extended Interneuronal Network of the Dentate Gyrus [PDF]

Cell Reports, 2017
Local interneurons control principal cells within individual brain areas, but anecdotal observations indicate that interneuronal axons sometimes extend beyond strict anatomical boundaries. Here, we use the case of the dentate gyrus (DG) to show that boundary-crossing interneurons with cell bodies in CA3 and CA1 constitute a numerically significant and ...
Ivan Soltesz, Jack M. Parent, Csaba Varga, Mikko Oijala, Gergely G. Szabo, Xi Du   +5 more
openaire   +4 more sources