Results 21 to 30 of about 139,984 (307)

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

Journal of Neuroscience, 1996
The hippocampus is one of the few areas of the rodent brain that continues to produce neurons postnatally. Neurogenesis reportedly persists in rats up to 11 months of age.
H. Georg, Kuhn, Heather, Dickinson-Anson, Fred, H. Gage   +5 more
semanticscholar   +1 more source

Transmembrane protein 108 involves in adult neurogenesis in the hippocampal dentate gyrus

Cell & Bioscience, 2019
Background Transmembrane protein 108 (Tmem108) is a risk gene of psychiatric diseases including schizophrenia, bipolar disorder and major depression disorder. However, the pathophysiological mechanisms of Tmem108 are largely unknown.
Zheng Yu, Dong Lin, Yanzi Zhong, Bin Luo, Shengsheng Liu, Erkang Fei, Xinsheng Lai, Suqi Zou, Shunqi Wang   +8 more
doaj   +1 more source

Temporal changes in prosaposin expression in the rat dentate gyrus after birth. [PDF]

PLoS ONE, 2014
Neurogenesis in the hippocampal dentate gyrus occurs constitutively throughout postnatal life. Adult neurogenesis includes a multistep process that ends with the formation of a postmitotic and functionally integrated new neuron. During adult neurogenesis,
Midori Morishita, Hiroaki Nabeka, Tetsuya Shimokawa, Kyojy Miyawaki, Takuya Doihara, Shouichiro Saito, Naoto Kobayashi, Seiji Matsuda   +7 more
doaj   +1 more source

Decrease in glucose transporter 1 levels and translocation of glucose transporter 3 in the dentate gyrus of C57BL/6 mice and gerbils with aging

Laboratory Animal Research, 2018
In the present study, we compared the cell-specific expression and changes protein levels in the glucose transporters (GLUTs) 1 and 3, the major GLUTs in the mouse and gerbil brains using immuno-histochemistry and Western blot analysis. In both mouse and
Kwon Young Lee, Dae Young Yoo, Hyo Young Jung, Loktam Baek, Hangyul Lee, Hyun Jung Kwon, Jin Young Chung, Seok Hoon Kang, Dae Won Kim, In Koo Hwang, Jung Hoon Choi   +10 more
doaj   +1 more source

Terminal Differentiation of Adult Hippocampal Progenitor Cells Is a Step Functionally Dissociable from Proliferation and Is Controlled by Tis21, Id3 and NeuroD2

Frontiers in Cellular Neuroscience, 2017
Cell proliferation and differentiation are interdependent processes. Here, we have asked to what extent the two processes of neural progenitor cell amplification and differentiation are functionally separated.
Laura Micheli, Manuela Ceccarelli, Roberta Gioia, Giorgio D’Andrea, Stefano Farioli-Vecchioli, Marco Costanzi, Daniele Saraulli, Daniele Saraulli, Vincenzo Cestari, Felice Tirone   +9 more
doaj   +1 more source

Combined role of seizure-induced dendritic morphology alterations and spine loss in newborn granule cells with mossy fiber sprouting on the hyperexcitability of a computer model of the dentate gyrus. [PDF]

PLoS Computational Biology, 2014
Temporal lobe epilepsy strongly affects hippocampal dentate gyrus granule cells morphology. These cells exhibit seizure-induced anatomical alterations including mossy fiber sprouting, changes in the apical and basal dendritic tree and suffer substantial ...
Julian Tejada, Norberto Garcia-Cairasco, Antonio C Roque   +2 more
doaj   +1 more source

Postnatal and Adult Neurogenesis in Mammals, Including Marsupials

Cells, 2022
In mammals, neurogenesis occurs during both embryonic and postnatal development. In eutherians, most brain structures develop embryonically; conversely, in marsupials, a number of brain structures develop after birth.
Katarzyna Bartkowska, Beata Tepper, Krzysztof Turlejski, Ruzanna Djavadian   +3 more
doaj   +1 more source

Pemberian Asam Valproat pada Induk Tikus Bunting Menghambat Sintesis Insulin pada Sel Otak Anak Tikus

Majalah Kedokteran Bandung, 2017
Asam valproat memengaruhi aktivitas histone deacetylase yang berperan dalam ekspresi gen selama organogenesis. Insulin berperan dalam proliferasi dan diferensiasi sel-sel saraf dentate gyrus hipokampus.
Komariah Komariah, Bambang Kiranadi, Adi Winanto, Wasmen Manalu, Ekowati Handharyani   +4 more
doaj   +1 more source

Adult-born hippocampal neurons bidirectionally modulate entorhinal inputs into the dentate gyrus

Science, 2019
Afferents modulate newborn neurons What is the role of adult neurogenesis in learning, memory, and mood? Luna et al. found that adult-born neurons either inhibited or excited the dentate gyrus, depending on whether synaptic inputs originated from the ...
V. Luna, C. Anacker, N. Burghardt, Hameda Khandaker, Valentine Andreu, A. Millette, Paige Leary, R. Ravenelle, Jessica C. Jimenez, Alessia Mastrodonato, C. Denny, A. Fenton, H. Scharfman, R. Hen   +13 more
semanticscholar   +1 more source

Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus

Laboratory Animal Research, 2018
Bacopa monnieri is a medicinal plant with a long history of use in Ayurveda, especially in the treatment of poor memory and cognitive deficits. In the present study, we hypothesized that Bacopa monnieri extract (BME) can improve memory via increased cell
Hyun Jung Kwon, Hyo Young Jung, Kyu Ri Hahn, Woosuk Kim, Jong Whi Kim, Dae Young Yoo, Yeo Sung Yoon, In Koo Hwang, Dae Won Kim   +8 more
doaj   +1 more source