Results 21 to 30 of about 63,053 (291)

The Mechanism of Rate Remapping in the Dentate Gyrus [PDF]

Neuron, 2010
Rate remapping is a recently revealed neural code in which sensory information modulates the firing rate of hippocampal place cells. The mechanism underlying rate remapping is unknown. Its characteristic modulation, however, must arise from the interaction of the two major inputs to the hippocampus, the medial entorhinal cortex (MEC), in which grid ...
César Rennó-Costa, Paul F. M. J. Verschure, Paul F. M. J. Verschure, John E. Lisman   +3 more
openaire   +3 more sources

Pemberian Asam Valproat pada Induk Tikus Bunting Menghambat Sintesis Insulin pada Sel Otak Anak Tikus

Majalah Kedokteran Bandung, 2017
Asam valproat memengaruhi aktivitas histone deacetylase yang berperan dalam ekspresi gen selama organogenesis. Insulin berperan dalam proliferasi dan diferensiasi sel-sel saraf dentate gyrus hipokampus.
Komariah Komariah, Bambang Kiranadi, Adi Winanto, Wasmen Manalu, Ekowati Handharyani   +4 more
doaj   +1 more source

Postnatal and Adult Neurogenesis in Mammals, Including Marsupials

Cells, 2022
In mammals, neurogenesis occurs during both embryonic and postnatal development. In eutherians, most brain structures develop embryonically; conversely, in marsupials, a number of brain structures develop after birth.
Katarzyna Bartkowska, Beata Tepper, Krzysztof Turlejski, Ruzanna Djavadian   +3 more
doaj   +1 more source

Sex steroids and the dentate gyrus [PDF]

, 2007
In the late 1980s, the finding that the dentate gyrus contains more granule cells in the male than in the female of certain mouse strains provided the first indication that the dentate gyrus is a significant target for the effects of sex steroids during development. Gonadal hormones also play a crucial role in shaping the function and morphology of the
Teresa A. Milner, Teresa A. Milner, Tibor Hajszan, Csaba Leranth   +3 more
openaire   +2 more sources

Exercise-Induced Activated Platelets Increase Adult Hippocampal Precursor Proliferation and Promote Neuronal Differentiation

Stem Cell Reports, 2019
Summary: Physical activity is a strong positive physiological modulator of adult neurogenesis in the hippocampal dentate gyrus. Although the underlying regulatory mechanisms are still unknown, systemic processes must be involved.
Odette Leiter, Suse Seidemann, Rupert W. Overall, Beáta Ramasz, Nicole Rund, Sonja Schallenberg, Tatyana Grinenko, Ben Wielockx, Gerd Kempermann, Tara L. Walker   +9 more
doaj   +1 more source

Dentate gyrus is needed for memory retrieval. [PDF]

Mol Psychiatry
AbstractThe hippocampus is crucial for acquiring and retrieving episodic and contextual memories. In previous studies, the inactivation of dentate gyrus (DG) neurons by chemogenetic- and optogenetic-mediated hyperpolarization led to opposing conclusions about DG’s role in memory retrieval.
Carretero-Guillén A, Treviño M, Gómez-Climent MÁ, Dogbevia GK, Bertocchi I, Sprengel R, Larkum ME, Vlachos A, Gruart A, Delgado-García JM, Hasan MT.   +10 more
europepmc   +7 more sources

Microelastic mapping of the rat dentate gyrus [PDF]

Royal Society Open Science, 2016
The lineage commitment of many cultured stem cells, including adult neural stem cells (NSCs), is strongly sensitive to the stiffness of the underlying extracellular matrix. However, it remains unclear how well the stiffness ranges explored in culture align with the microscale stiffness values stem cells actually encounter within their ...
Tomás Luque, Michael S. Kang, David V. Schaffer, Sanjay Kumar   +3 more
openaire   +3 more sources

Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus

Laboratory Animal Research, 2018
Bacopa monnieri is a medicinal plant with a long history of use in Ayurveda, especially in the treatment of poor memory and cognitive deficits. In the present study, we hypothesized that Bacopa monnieri extract (BME) can improve memory via increased cell
Hyun Jung Kwon, Hyo Young Jung, Kyu Ri Hahn, Woosuk Kim, Jong Whi Kim, Dae Young Yoo, Yeo Sung Yoon, In Koo Hwang, Dae Won Kim   +8 more
doaj   +1 more source

Dentate gyrus volume deficit in schizophrenia [PDF]

Psychological Medicine, 2019
AbstractBackgroundSchizophrenia is associated with robust hippocampal volume deficits but subregion volume deficits, their associations with cognition, and contributing genes remain to be determined.MethodsHippocampal formation (HF) subregion volumes were obtained using FreeSurfer 6.0 from individuals with schizophrenia (n= 176, mean age ±s.d.= 39.0 ...
Soichiro Nakahara, Jessica A. Turner, Vince D. Calhoun, Kelvin O. Lim, Bryon Mueller, Juan R. Bustillo, Daniel S. O'Leary, Sarah McEwen, James Voyvodic, Aysenil Belger, Daniel H. Mathalon, Judith M. Ford, Fabio Macciardi, Mitsuyuki Matsumoto, Steven G. Potkin, Theo G. M. van Erp   +15 more
openaire   +5 more sources

Contribution of Egr1/Zif268 to activity-dependent Arc/Arg3.1 transcription in the dentate gyrus and area CA1 of the hippocampus

Frontiers in Behavioral Neuroscience, 2011
Egr1, a member of the Egr family of transcription factors, and Arc are immediate early genes known to play major roles in synaptic plasticity and memory.
Zsuzsa ePenke, Zsuzsa ePenke, Carine eChagneau, Carine eChagneau, Serge eLaroche, Serge eLaroche   +5 more
doaj   +1 more source