Results 41 to 50 of about 131,553 (328)

Dentate gyrus volume deficit in schizophrenia [PDF]

Psychological Medicine, 2019
AbstractBackgroundSchizophrenia is associated with robust hippocampal volume deficits but subregion volume deficits, their associations with cognition, and contributing genes remain to be determined.MethodsHippocampal formation (HF) subregion volumes were obtained using FreeSurfer 6.0 from individuals with schizophrenia (n= 176, mean age ±s.d.= 39.0 ...
Soichiro Nakahara, Jessica A. Turner, Vince D. Calhoun, Kelvin O. Lim, Bryon Mueller, Juan R. Bustillo, Daniel S. O'Leary, Sarah McEwen, James Voyvodic, Aysenil Belger, Daniel H. Mathalon, Judith M. Ford, Fabio Macciardi, Mitsuyuki Matsumoto, Steven G. Potkin, Theo G. M. van Erp   +15 more
openaire   +5 more sources

Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus

Nature Communications, 2018
Early life experience influences stress reactivity and mental health through effects on cognitive-emotional functions that are, in part, linked to gene expression in the dorsal and ventral hippocampus.
Tie-Yuan Zhang, C. Keown, Xianglan Wen, Junhao Li, D. Vousden, C. Anacker, Urvashi Bhattacharyya, R. Ryan, J. Diorio, Nicholas O’Toole, J. Lerch, E. Mukamel, M. Meaney   +12 more
semanticscholar   +1 more source

Intracellular mechanisms underlying the nicotinic enhancement of LTP in the rat dentate gyrus [PDF]

, 2008
We have previously shown that activation of nicotinic acetylcholine receptors (nAChRs) enhanced long-term potentiation (LTP) in the rat dentate gyrus in vitro via activation of α7 nAChR. In the present studies, mechanisms underlying the acute and chronic
Abel, Arendt, Atack, Bain, Bear, Blanquet, Bliss, Blitzer, Blitzer, Bogan, Casey, Charpantier, Cho, Dajas-Bailador, Davies, Davis, Decker, Dhavan, Dominguez del Toro, English, Faghih, Fujii, Giovannini, Gray, Hope, Huang, Huang, Hunter, Hurst, Ji, Jones, Kawakami, Kelly, Kihara, Klein, Krause, Le Novere, Levin, Li, Liston, Lu, Man, Mann, Marrero, Matsuyama, Matthies, Meriane, Opazo, O’Dell, Peavy, Picciotto, Polesskaya, Polesskaya, Radcliffe, Roberson, Rush, Salazar, Sanna, Sanna, Santos, Seguela, Sharifzadeh, Sharifzadeh, Sharma, Shaw, Shaw, Sweatt, Takada-Takatori, Tominaga-Yoshino, Wada, Wang, Wang, Welsby, Welsby, Whitehouse, Woo, Wu, Yang, Ying, Yu, Zhang, Zwart   +81 more
core   +1 more source

Extended Interneuronal Network of the Dentate Gyrus [PDF]

Cell Reports, 2017
Local interneurons control principal cells within individual brain areas, but anecdotal observations indicate that interneuronal axons sometimes extend beyond strict anatomical boundaries. Here, we use the case of the dentate gyrus (DG) to show that boundary-crossing interneurons with cell bodies in CA3 and CA1 constitute a numerically significant and ...
Ivan Soltesz, Jack M. Parent, Csaba Varga, Mikko Oijala, Gergely G. Szabo, Xi Du   +5 more
openaire   +4 more sources

Dentate gyrus and spatial behaviour

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2009
This article reviews evidence from studies employing colchicine-induced granule cell loss in the adult rat brain, and irradiation-induced hypoplasia of the neonatal dentate gyrus, on the performance of spatial and non-spatial behavioral tasks. The general picture emerging from this analysis reveals that the dentate gyrus granule cells are critically ...
Gilberto Fernando Xavier, Valéria Catelli Infantozzi Costa   +1 more
openaire   +3 more sources

Obligatory roles of dopamine D1 receptors in the dentate gyrus in antidepressant actions of a selective serotonin reuptake inhibitor, fluoxetine

Molecular Psychiatry, 2018
Depression is a leading cause of disability. Current pharmacological treatment of depression is insufficient, and development of improved treatments especially for treatment-resistant depression is desired.
T. Shuto, M. Kuroiwa, N. Sotogaku, Y. Kawahara, Y. Oh, Jin-Hyeok Jang, Chang-Hoon Shin, Y. Ohnishi, Yuuki Hanada, T. Miyakawa, Yong Kim, P. Greengard, A. Nishi   +12 more
semanticscholar   +1 more source

Alteration of dentate gyrus astrocytes in diabetic rats: Protective role of Urtica dioica [PDF]

, 2011
Diabetes mellitus can cause astrocytes alterations in the central nervous system. Urtica dioica (Nettle) is among several species listed for their use against diabetes in folk medicine.
Ghafari, S., Golalipour, M.J., Kaboli, S., Latifimoghadam, M.H.   +3 more
core   +1 more source

Inhibitory Gatin in Dentate Gyrus

, 2021
Trabajo presentado en la 30th Annual Computational Neuroscience Meeting (CNS*2021), celebrada online del 3 al 7 de julio de 2021.
Estarellas, Cristian, Mirasso, Claudio R., Canals, Santiago   +2 more
openaire   +3 more sources

Rapid stimulation of human dentate gyrus function with acute mild exercise

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Our previous work has shown that mild physical exercise can promote better memory in rodents. Here, we use functional MRI in healthy young adults to assess the immediate impact of a short bout of mild exercise on the brain mechanisms ...
Kazuya Suwabe, Kyeongho Byun, Kazuki Hyodo, Zachariah M. Reagh, Jared M. Roberts, A. Matsushita, K. Saotome, Genta Ochi, Takemune Fukuie, Kenji Suzuki, Y. Sankai, M. Yassa, H. Soya   +12 more
semanticscholar   +1 more source

Contribution of Egr1/Zif268 to activity-dependent Arc/Arg3.1 transcription in the dentate gyrus and area CA1 of the hippocampus

Frontiers in Behavioral Neuroscience, 2011
Egr1, a member of the Egr family of transcription factors, and Arc are immediate early genes known to play major roles in synaptic plasticity and memory.
Zsuzsa ePenke, Zsuzsa ePenke, Carine eChagneau, Carine eChagneau, Serge eLaroche, Serge eLaroche   +5 more
doaj   +1 more source