Learning Sparse Spatial Codes for Cognitive Mapping Inspired by Entorhinal-Hippocampal Neurocircuit [PDF]
arXiv, 2019 The entorhinal-hippocampal circuit plays a critical role in higher brain functions, especially spatial cognition. Grid cells in the medial entorhinal cortex (MEC) periodically fire with different grid spacing and orientation, which makes a contribution that place cells in the hippocampus can uniquely encode locations in an environment.
arxiv
The effect of spatial learning on the number of astrocytes in rat dentate gyrus [PDF]
, 2007 In this study, we evaluated the effect of spatial learning on the number of astrocytes in the rat dentate gyrus with Morris water maze. Fifteen male albino Wistar rats were divided into three groups as control, reference memory and working memory groups.
Hosseini, A. +3 more
core
TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death [PDF]
, 1997 Newborn mice carrying targeted mutations in genes encoding neurotrophins or their signaling Trk receptors display severe neuronal deficits in the peripheral nervous system but not in the CNS. In this study, we show that trkB (¿/¿) mice have a significant
Alcántara Horrillo, Soledad +5 more
core +1 more source
Deep Cerebellar Nuclei Segmentation via Semi-Supervised Deep Context-Aware Learning from 7T Diffusion MRI [PDF]
arXiv, 2020 Deep cerebellar nuclei are a key structure of the cerebellum that are involved in processing motor and sensory information. It is thus a crucial step to accurately segment deep cerebellar nuclei for the understanding of the cerebellum system and its utility in deep brain stimulation treatment.
arxiv
Cortistain is expressed in a distinct subset of cortical interneurons [PDF]
, 1997 Cortistatin is a presumptive neuropeptide that shares 11 of its 14 amino acids with somatostatin. In contrast to somatostatin, administration of cortistatin into the rat brain ventricles specifically enhances slow wave sleep, apparently by antagonizing ...
Alcántara Horrillo, Soledad +8 more
core
Enhanced hippocampal long-term potentiation and spatial learning in aged 11ß-hydroxysteroid dehydrogenase type 1 knock-out mice [PDF]
, 2007 Glucocorticoids are pivotal in the maintenance of memory and cognitive functions as well as other essential physiological processes including energy metabolism, stress responses, and cell proliferation.
Brownstein, D. +9 more
core +2 more sources
Neurogenesis and multiple plasticity mechanisms enhance associative memory retrieval in a spiking network model of the hippocampus [PDF]
arXiv, 2017 Hippocampal CA3 is crucial for the formation of long-term associative memory. It has a heavily recurrent connectivity, and memories are thought to be stored as memory engrams in the CA3. However, despite its importance for memory storage and retrieval, spiking network models of the CA3 to date are relatively small-scale, and exist as only proof-of ...
arxiv
Neurogenesis-Inspired Dictionary Learning: Online Model Adaption in a Changing World [PDF]
arXiv, 2017 In this paper, we focus on online representation learning in non-stationary environments which may require continuous adaptation of model architecture. We propose a novel online dictionary-learning (sparse-coding) framework which incorporates the addition and deletion of hidden units (dictionary elements), and is inspired by the adult neurogenesis ...
arxiv
Recognition Memory Dysfunction Relates to Hippocampal Subfield Volume: A Study of Cognitively Normal and Mildly Impaired Older Adults. [PDF]
, 2018 ObjectivesThe current study examined recognition memory dysfunction and its neuroanatomical substrates in cognitively normal older adults and those diagnosed with mild cognitive impairment (MCI).MethodsParticipants completed the Mnemonic Similarity Task,
Bennett, Ilana J +2 more
core +2 more sources
Modulation of adult-born neurons in the inflamed hippocampus. [PDF]
, 2013 Throughout life new neurons are continuously added to the hippocampal circuitry involved with spatial learning and memory. These new cells originate from neural precursors in the subgranular zone of the dentate gyrus, migrate into the granule cell layer,
Belarbi, Karim, Rosi, Susanna
core +2 more sources