Temporary changes in large-scale memory neural networks after fear learning and extinction in healthy adults [PDF]
The analysis of the functional connectivity of brain sections associated with fear-conditioned training is one of the methods of study of memory neural networks. Before, the majority of studies focused on the functional connectivity of the brain regions that are known for emotional processing such as amygdala and areas of the ventromedial prefrontal ...
arxiv
Clonal analysis of newborn hippocampal dentate granule cell proliferation and development in temporal lobe epilepsy [PDF]
Hippocampal dentate granule cells are among the few neuronal cell types generated throughout adult life in mammals. In the normal brain, new granule cells are generated from progenitors in the subgranular zone and integrate in a typical fashion. During the development of epilepsy, granule cell integration is profoundly altered. The new cells migrate to
arxiv
Neural Modulation Alteration to Positive and Negative Emotions in Depressed Patients: Insights from fMRI Using Positive/Negative Emotion Atlas [PDF]
Background: Although it has been noticed that depressed patients show differences in processing emotions, the precise neural modulation mechanisms of positive and negative emotions remain elusive. FMRI is a cutting-edge medical imaging technology renowned for its high spatial resolution and dynamic temporal information, making it particularly suitable ...
arxiv +1 more source
Radiation-induced lowered neurogenesis associated with shortened latency of inhibitory avoidance memory response [PDF]
The neural system is less sensitive to radiation than other late-responding organs and tissues such as the kidney and lung. The generation of new neurons in the adult mammalian brain has been documented in several works.
Azami, N.S.+3 more
core
Identifying Brain Image Level Endophenotypes in Epilepsy [PDF]
A brain wide association study (BWAS) based on the logistic regression was first developed and applied to a large population of epilepsy patients (168) and healthy controls (136). It was found that the most significant links associated with epilepsy are those bilateral links with regions mainly belonging to the default mode network and subcortex, such ...
arxiv
Dentate total molecular layer interneurons mediate cannabinoid-sensitive inhibition. [PDF]
Activity of the dentate gyrus, which gates information flow to the hippocampus, is under tight inhibitory regulation by interneurons with distinctive axonal projections, intrinsic and synaptic characteristics and neurochemical identities. Total molecular
Proddutur, Archana+3 more
core
Effects of nicotine administration on amyloid precursor protein metabolism, neural cell genesis and acquisition of spatial memory [PDF]
Nicotine is reported to improve learning and memory in experimental animals. Improved learning and memory has also been related to increased neural cell genesis in the dentate gyrus of the brain hippocampal formation.
Scerri, Charles
core
Plasticity of GABA(B) receptor-mediated heterosynaptic interactions at mossy fibers after status epilepticus [PDF]
Several neurotransmitters, including GABA acting at presynaptic GABAB receptors, modulate glutamate release at synapses between hippocampal mossy fibers and CA3 pyramidal neurons.
Bowery, N.G.+5 more
core
Targeting tauopathy with engineered tau-degrading intrabodies [PDF]
BACKGROUND: The accumulation of pathological tau is the main component of neurofibrillary tangles and other tau aggregates in several neurodegenerative diseases, referred to as tauopathies.
Gallardo, Gilbert+7 more
core +1 more source
A Coupled Neural Field Model for the Standard Consolidation Theory [PDF]
The standard consolidation theory states that short-term memories located in the hippocampus enable the consolidation of long-term memories in the neocortex. In other words, the neocortex slowly learns long-term memories with a transient support of the hippocampus that quickly learns unstable memories.
arxiv