Results 51 to 60 of about 61,176 (239)
Journal of Pharmacological Sciences, 2013 Edaravone is clinically used in Japan for treatment of patients with acute cerebral infarction. To clarify the effect of edaravone on neurogenesis in the hippocampus following neuronal injury in the hippocampal dentate gyrus, we investigated the effect ...
Maho Kikuta +7 more
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PLoS Biology, 2010 The dentate gyrus has an important role in learning and memory, and adult neurogenesis in the subgranular zone of the dentate gyrus may play a role in the acquisition of new memories.
Alfonso Lavado +4 more
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Reassessing pattern separation in the dentate gyrus [PDF]
Frontiers in Behavioral Neuroscience, 2013 The dentate gyrus (DG) is postulated to be a “pattern separator” (Marr, 1971; Rolls, 1989a,b, 1990; Treves and Rolls, 1994). Yet, the definition of pattern separation has become a haze, with researchers using the term interchangeably to describe computational processes, changes in cell ensemble activity, and even behavioral phenomena (Leutgeb et al ...
openaire +4 more sources
Frontiers in Molecular Neuroscience, 2023 Adult neurogenesis is a persistent phenomenon in mammals that occurs in select brain structures in both healthy and diseased brains. The tumor suppressor gene, phosphatase and tensin homolog deleted on chromosome 10 (Pten) has previously been found to ...
Sarah E. Latchney +4 more
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Tractography-Based Parcellation of Cerebellar Dentate Nuclei via a Deep Nonnegative Matrix Factorization Clustering Method [PDF]
arXiv, 2022 As the largest human cerebellar nucleus, the dentate nucleus (DN) functions significantly in the communication between the cerebellum and the rest of the brain. Structural connectivity-based parcellation has the potential to reveal the topography of the DN and enable the study of its subregions.
arxiv
Journal of Pharmacological Sciences, 2014 .: Aripiprazole is used clinically as an atypical antipsychotic. We evaluated the effect of in vivo treatment with aripiprazole on the proliferation and differentiation of neural stem/progenitor cells in a mouse model, trimethyltin-induced neuronal loss ...
Masanori Yoneyama +7 more
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Status epilepticus induced Gadd45b is required for augmented dentate neurogenesis
Stem Cell Research, 2020 In animal models with temporal lobe epilepsy (TLE), the status epilepticus (SE) leads to a dramatic increase in number of newly born neuron in the subgranular zone (SGZ) of dentate gyrus.
Xin-Li Xiao +8 more
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ASN Neuro, 2019 There is growing evidence from epidemiological studies that especially midlife physical activity might exert a positive influence on the risk and progression of Alzheimer’s disease.
Anna-Lina Gerberding +4 more
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Морфологія, 2019 Background. The effect of labor stimulation on the brain structure still remains an unexplored issue. Objective. To determine the morphological hippocampus and dentate gyrus changes in laboratory rats on the first day of life after intravaginal injection
E. A. Hrygorieva, I. Y. Mamay
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Computational Pattern Separation Models of Dentate Gyrus Neural Subpopulation in the Hippocampus
Caspian Journal of Neurological Sciences, 2022 Hippocampus is a part of the brain that has an essential role in memory and learning. It is involved in many cognitive and behavioral phenomena, including the pattern separation process: the ability to distinguish patterns with very high similarity.
Nazal Modhej +3 more
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