Results 21 to 30 of about 3,794 (158)

Towards a New Concept of Regenerative Endodontics Based on Mesenchymal Stem Cell-Derived Secretomes Products

open access: yesBioengineering, 2022
The teeth, made up of hard and soft tissues, represent complex functioning structures of the oral cavity, which are frequently affected by processes that cause structural damage that can lead to their loss.
Luis A. Costa   +3 more
doaj   +1 more source

High pH-Sensitive Store-Operated Ca2+ Entry Mediated by Ca2+ Release-Activated Ca2+ Channels in Rat Odontoblasts

open access: yesFrontiers in Physiology, 2018
Odontoblasts play a crucial role in dentin formation and sensory transduction following the application of stimuli to the dentin surface. Various exogenous and endogenous stimuli elicit an increase in the intracellular free calcium concentration ([Ca2+]i)
Maki Kimura   +7 more
doaj   +1 more source

Protein S100-A7 Derived from Digested Dentin Is a Critical Molecule for Dentin Pulp Regeneration

open access: yesCells, 2019
Dentin consists of inorganic hard tissue and organic dentin matrix components (DMCs). Various kinds of bioactive molecules are included in DMCs and some of them can be released after digestion by endogenous matrix metalloproteinases (MMPs) in the caries ...
Shungo Komichi   +8 more
doaj   +1 more source

The effects of 4-Phenylbutyric acid on ER stress during mouse tooth development

open access: yesFrontiers in Physiology, 2023
Introduction: During tooth development, proper protein folding and trafficking are significant processes as newly synthesized proteins proceed to form designated tissues.
Eui-Seon Lee   +12 more
doaj   +1 more source

Sequentially Functional And Asthetic Restoration Of Severe Dentin Dysplasia

open access: yesInternational Dental Journal
Introduction: This case report introduced sequentially functional and aesthetic restoration on a patient with dentin dysplasia type II (DD-II) accompanied by severe tooth wear. Case description: An eight-year-old girl with severe tooth wear presented for
Xuemei Liu, Xu Chen
doaj   +1 more source

Phosphophoryn and Dentin Sialoprotein Effects on Dental Pulp Cell Migration, Proliferation, and Differentiation

open access: yesDentistry Journal, 2018
Phosphophoryn (PP) and dentin sialoprotein (DSP) are two of the most abundant dentin matrix non-collagenous proteins, and are derived from dentin sialoprotein-phosphophoryn (DSP-PP) mRNA.
Shu-Feng Chuang   +3 more
doaj   +1 more source

Promoting dentinogenesis of DPSCs through inhibiting microRNA-218 by using magnetic nanocarrier delivery

open access: yesJournal of the Formosan Medical Association, 2019
Purpose: The purposes of this study are to explore the roles of microRNA-218 (miR-218) delivered by a newly designed magnetic nanocarrier: GCC-Fe3O4 (GCC-Fe) in dentinogenesis potentials of human dental pulp stem cells (DPSCs).
Karen Chang   +3 more
doaj   +1 more source

Functional role of inorganic trace elements on enamel and dentin formation: A review

open access: yesJournal of Pharmacy and Bioallied Sciences, 2021
Calcium and phosphate are the major components of hydroxyapatite crystals that form the inorganic portion of the teeth. Apart from these, certain elements are present in little amounts in enamel and dentin of the human teeth.
Izaz Shaik   +6 more
doaj   +1 more source

ISOLATED DENTINOGENESIS IMPERFECTA AND IN ASSOCIATION WITH OSTEOGENESIS IMPERFECTA – A LITERATURE REVIEW [PDF]

open access: yesRomanian Medical Journal, 2018
Dental development is part of the craniofacial organogenesis, starting from the pluripotent cephalic neural crest cells, continuing with their movement towards the first pharyngeal arch and leading to the development of many elements of the ...
Andrei Kozma   +5 more
doaj   +1 more source

Role of the Demethylase AlkB Homolog H5 in the Promotion of Dentinogenesis

open access: yesFrontiers in Physiology, 2022
Dentinogenesis is a key process in tooth formation and is regulated by a series of pre- and post-transcriptional regulations. N6-methyl-adenosine (m6A), which is the most prevalent internal chemical modification that can be removed by the RNA demethylase
Cheng Tian   +12 more
doaj   +1 more source

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