Results 181 to 190 of about 54,854 (258)

Effective Reduction in Nuclear DNA Contamination Allows Sensitive Mitochondrial DNA Methylation Determination by LC-MS/MS. [PDF]

Int J Mol Sci
Liang L, González Molina LA, Jellema PG, van Faassen M, Otten LTA, Mennega KP, Hof IH, Dijck-Brouwer DAJ, Dolga AM, Rots MG, Niezen-Koning KE.   +10 more
europepmc   +1 more source

Artificial Mutations in the Nuclear Gene Encoding Mitochondrial RNA Polymerase Restore Pollen Fertility in Cytoplasmic Male Sterile Tomato

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1414-1427, March 2026.
ABSTRACT Cytoplasmic male sterility (CMS) and restorer of fertility (Rf) are important traits in F1 hybrid breeding. However, the CMS/Rf system has not been used in tomatoes because of the limited resources of Rf lines. In this study, we performed mutagenesis in tomato CMS seeds and successfully obtained 13 suppressor mutants with pollen fertility ...
Kosuke Kuwabara, Rika Nakajima, Van Bosstraeten Alexis Gaetan, Kentaro Ezura, Kinya Toriyama, Tohru Ariizumi, Kenta Shirasawa   +6 more
wiley   +1 more source

Targeting the Rift Valley Fever Virus Polymerase: Resistance Mechanisms and Structural Insights. [PDF]

ACS Infect Dis
Král' M, Das A, Kotačka T, Blahošová A, Liščáková V, Hodek J, Konvalinka J, Demo G, Kožíšek M.   +8 more
europepmc   +1 more source

Heterologous Production of Forskolin in Tobacco (Nicotiana tabacum) via Glandular Trichome Specific Engineering and Metabolic Flux Redirection

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1548-1563, March 2026.
ABSTRACT Plants are promising bioreactor for the sustainable and scalable production of high‐value natural bioactive compounds, because they can synthesise phytochemicals from CO2, light, water and minerals through their innate photosynthetic carbon assimilation machinery.
Xuan Sun, Xiuming Wu, Xun Jiang, Hongmei Huang, Aiguo Yang, Yiting Li, Zhenjun Fan, Aixia Chang, Changqing Yang   +8 more
wiley   +1 more source

Dysregulated methylation of the human BOLL promoter hinders germ cell development from spermatogonia to spermatids. [PDF]

Mol Biol Rep
Lin TY, Chen HY, Cheng YH, Lu CW, Ma HY, Hou HC, Lin YM, Lin SC, Cheng YS.   +8 more
europepmc   +1 more source

Deoxycytidine Analogue TAS-109 [PDF]

, 2020
openaire   +1 more source

Combining drugs that bypass p53 to treat TP53-mutated leukemias. [PDF]

Blood Adv
Biswas S, Zahran ZAM, Gu X, Cardone L, Marti R, Mouannes N, Stich M, Jain A, Fedorov K, Tomlinson B, Goldfinger M, Verma A, Saunthararajah Y.   +12 more
europepmc   +1 more source

CD47 Promotes, While Exposure to Apoptotic Cells Destroys the Fusion Program of Differentiating Myoblasts

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
(A) CD47, acting in a cis‐manner with integrins, promotes myoblast fusion. TSP‐1 serves as a bridging molecule for these proteins to recognize PS on the surface of the other fusing myoblasts. (B) Blocking of these signals by neutralizing antibodies reduces cell fusion. Inhibition of PIEZO1 activity by constantly expressed PS on apoptotic cells leads to
Maysaa Adil Ali, Albert Bálint Papp, Éva Garabuczi, Áron Károly Gere, Beatrix Dienes, Mónika Gönczi, György Vámosi, Krisztina Köröskényi, László Csernoch, Zsuzsa Szondy, Zsolt Sarang   +10 more
wiley   +1 more source

Solution-Phase Synthesis of Boranophosphate and Boranophosphate/Phosphorothioate/Phosphate Chimeric Oligonucleotides via the H-Boranophosphonate Method. [PDF]

J Org Chem
Takahashi Y, Kato I, Sato K, Wada T.
europepmc   +1 more source

Disruption of Hepatic Insulin Signaling Causes Phospholipid Dysregulation in Mice

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
Pan et al. demonstrate that disruption of hepatic insulin signaling by insulin receptor (IR) substrate (IRS1/2) deletion led to impaired PI3K‐AKT signaling, causing increased Foxo1 activation and TGF‐β1 expression, which dysregulated the expression of the key enzymes involving phospholipid biosynthesis and remodeling.
Quan Pan, Meixia Pan, Weiqi Ai, Wanbao Yang, Wen Jiang, Xianlin Han, Shaodong Guo   +6 more
wiley   +1 more source