Results 11 to 20 of about 101,166 (300)
Structure of acid deoxyribonuclease [PDF]
Nucleic Acids Research, 2017 Deoxyribonuclease II (DNase II) is also known as acid deoxyribonuclease because it has optimal activity at the low pH environment of lysosomes where it is typically found in higher eukaryotes.
A. Varela-Ramírez +6 more
semanticscholar +4 more sources
Rutin as Deoxyribonuclease I Inhibitor
Chemistry & Biodiversity, 2019 DNase I inhibitory potential of water extract of nine Hypericum species (H. umbellatum, H. barbatum, H. rumeliacum, H. rochelii, H. perforatum, H. tetrapterum, H. olympicum, H. hirsutum, H.
Ana Kolarević +7 more
semanticscholar +5 more sources
New therapy of pleural empyema by deoxyribonuclease
Brazilian Journal of Infectious Diseases, 2013 Empyema is a severe complication of different diseases and traumas. Management of this complication is difficult and should comprise general and local procedures. The general procedure is mainly based on administering wide-spectrum antibiotics.
Grzegorz Kacprzak +5 more
doaj +10 more sources
The Deoxyribonucleases of Streptococcus pyogenes
Journal of Biological Chemistry, 1964 Jeanette E. Winter, Alan W. Bernheimer
openalex +4 more sources
Activation of Deoxyribonucleases by Divalent Cations [PDF]
The Journal of General Physiology, 1962 The activation of DNase I by Mg, Mn, Co, Ni, Fe, Cd, Zn, Ba, Sr, Ca, and Cu ions has been studied by several methods, at different pH and salt concentrations. Mg, Mn, and Co are the best activators for initial stages of degradation. A synergistic effect is shown only by the pair Mg-Ca. Optimal pH of action is always situated at 6.5.
V. Desreux, R. Hacha, E. Frédéricq
openalex +5 more sources
Deoxyribonucleases and Their Applications in Biomedicine [PDF]
Biomolecules, 2020 Extracellular DNA, also called cell-free DNA, released from dying cells or activated immune cells can be recognized by the immune system as a danger signal causing or enhancing inflammation. The cleavage of extracellular DNA is crucial for limiting the inflammatory response and maintaining homeostasis.
Lucia Lauková +4 more
openaire +4 more sources
Pharmaceutics, 2021 Biofilms of Cutibacterium (C.) acnes (formerly Propionibacterium acnes) are responsible for the persistence and antibiotic resistance of acne vulgaris. In addition to the standard treatments for acne vulgaris, a common adjunctive treatment is the topical
Yi-Hsien Shih +5 more
doaj +1 more source
CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks
eLife, 2020 Type V CRISPR-Cas interference proteins use a single RuvC active site to make RNA-guided breaks in double-stranded DNA substrates, an activity essential for both bacterial immunity and genome editing.
Joshua C Cofsky +5 more
doaj +1 more source
The Specificity of Pancreatic Deoxyribonuclease [PDF]
European Journal of Biochemistry, 1973 The kinetics of degradation of calf thymus DNA by pancreatic DNAase has been investigated with the main purpose of providing the background for studying the specificity of the enzyme and its use in investigations of nucleotide sequences in DNA. The relationships between the hyperchromic shift or acid solubility and the reciprocal average degree of ...
S. D. Ehrlich +2 more
openaire +4 more sources
Metabolomic profiles are gender, disease and time specific in the interleukin-10 gene-deficient mouse model of inflammatory bowel disease. [PDF]
, 2013 Metabolomic profiling can be used to study disease-induced changes in inflammatory bowel diseases (IBD). The aim of this study was to investigate the difference in the metabolomic profile of males and females as they developed IBD.
Churchill, Thomas A +6 more
core +8 more sources