Dead or alive: Deoxyribonuclease I sensitive bacteria and implications for the sinus microbiome. [PDF]
Am J Rhinol Allergy, 2016 Willis AL +4 more
europepmc +4 more sources
Impaired deoxyribonuclease I activity in patients with inflammatory bowel diseases. [PDF]
Autoimmune Dis, 2011 Background and Aims. Deoxyribonuclease I (DNaseI) is an endonuclease that facilitates chromatin breakdown and promotes susceptibility to autoimmune disorders.
Malíčková K +10 more
europepmc +4 more sources
Recombinant Human Deoxyribonuclease I [PDF]
Pharmaceutical biotechnology, 2013 Human deoxyribonuclease I (DNase I) is an endonuclease that catalyzes the hydrolysis of extracellular DNA and is just one of the numerous types of nucleases found in nature. The enzymatic mechanism for a single turnover is reasonably well understood based on biochemical and structural studies that are consistent with divalent metal ion dependent ...
Robert A. Lazarus, Jeffrey S. Wagener
semanticscholar +4 more sources
Rutin as Deoxyribonuclease I Inhibitor
Chemistry & Biodiversity, 2019 AbstractDNase I inhibitory potential of water extract of nine Hypericum species (H. umbellatum, H. barbatum, H. rumeliacum, H. rochelii, H. perforatum, H. tetrapterum, H. olympicum, H. hirsutum, H. linarioides) and the most important Hypericum secondary metabolites (hypericin, hyperforin, quercetin, and rutin) was investigated.
Ana Kolarevic +7 more
openaire +5 more sources
Actin Is the Naturally Occurring Inhibitor of Deoxyribonuclease I [PDF]
Proceedings of the National Academy of Sciences, 1974 Various tissues and cells in culture contain a specific inhibitor of DNase I (EC 3.1.4.5). In this paper evidence is presented that this inhibitor is actin, one of the major structural proteins of muscle and nonmuscle cells. ( a ) The inhibitor is a major cellular component constituting 5-10% of the soluble protein.
Lazarides, Elias, Lindberg, Uno
openaire +6 more sources
EVALUATION OF EXTRACELLULAR DEOXYRIBONUCLEASE ACTIVITY IN PSEUDOMONAS [PDF]
Journal of Bacteriology, 1962 Streitfeld, MurrayM. (University of Miami, Coral Gables, Fla.),Edward M. Hoffmann, and Herbert M. Janklow. Evaluation of extracellular deoxyribonuclease activity inPseudomonas. J. Bacteriol.84:77–80. 1962.—Of 23 strains ofP. aeruginosaisolated from pathological processes, 22 strains, representative of at least nine different somatic antigen types, were
Murray M. Streitfeld +2 more
openalex +4 more sources
A deoxyribonuclease I from rice bran [PDF]
Journal of the Faculty of Agriculture, Kyushu University, 1965 Jun‐Ichiro Mukai
openalex +3 more sources
A fluorescent biosensor for cardiac biomarker myoglobin detection based on carbon dots and deoxyribonuclease I-aided target recycling signal amplification. [PDF]
RSC Adv, 2019 A sensitive biosensor using carbon dots and deoxyribonuclease I-aided target recycling signal amplification has been developed to detect myoglobin (MB), which is an important cardiac biomarker and plays a major role in the diagnosis of acute myocardial ...
Chen J +7 more
europepmc +2 more sources
Ultrasensitive fluorescent aptasensor for MUC1 detection based on deoxyribonuclease I-aided target recycling signal amplification. [PDF]
RSC Adv, 2018 A novel sensing strategy for sensitive detection of mucin 1 protein (MUC1) based on deoxyribonuclease I-aided target recycling signal amplification was proposed.
Zhang J +8 more
europepmc +2 more sources
Evaluation of the functional effects of genetic variants‒missense and nonsense SNPs, indels and copy number variations‒in the gene encoding human deoxyribonuclease I potentially implicated in autoimmunity. [PDF]
Sci Rep, 2019 Genetic variants, such as single nucleotide polymorphisms (SNPs), in the deoxyribonuclease I (DNase I) gene which remarkably reduce or abolish the activity are assumed to be substantially responsible for the genetic backgrounds determining susceptibility
Ueki M +8 more
europepmc +2 more sources