Penicillides from Penicillium and Talaromyces: Chemical Structures, Occurrence and Bioactivities [PDF]
Penicillide is the founder product of a class of natural products of fungal origin. Although this compound and its analogues have been identified from taxonomically heterogeneous fungi, they are most frequently and typically reported from the species of ...
Maria Michela Salvatore +3 more
doaj +2 more sources
Curdepsidones B–G, Six Depsidones with Anti-Inflammatory Activities from the Marine-Derived Fungus Curvularia sp. IFB-Z10 [PDF]
Six new depsidones, curdepsidones B−G (1−6), were obtained from the marine-derived fungus Curvularia sp. IFB-Z10. Their planar structures were determined by comprehensive analysis of HRESIMS and 1D/2D-NMR data.
Yi Ding +5 more
doaj +2 more sources
A Novel b-Orcinol Depsidone of Lichen Lobaria pulmonaria [PDF]
In continuation of our phytochemical survey of Lobaria pulmonaria has led to the identification of deoxystictic acid in this foliose lichen species for the first time. The isolated β-orcinol depsidone showed moderate anti-hydroxyl radical activity using fluorescence spectroscopy at in vitro conditions.
Boris Pejin +4 more
openalex +3 more sources
Extraction of lichen bioactive compounds using volatile natural deep eutectic solvents and comparative analytical approaches [PDF]
Lichens are a source of bioactive secondary metabolites with different pharmacological activities. However, these metabolites are challenging regarding their extraction.
S. Dresler +9 more
doaj +2 more sources
Unveiling the therapeutic potential of Lobaria extract and its depsides/depsidones in combatting Aβ42 peptides aggregation and neurotoxicity in Alzheimer’s disease [PDF]
Background: The development of effective inhibitors that can inhibit amyloid β (Aβ) peptides aggregation and promote neurite outgrowth is crucial for the possible treatment of Alzheimer’s disease (AD).
Meixia Yang +15 more
doaj +2 more sources
Protocetraric and Salazinic Acids as Potential Inhibitors of SARS-CoV-2 3CL Protease: Biochemical, Cytotoxic, and Computational Characterization of Depsidones as Slow-Binding Inactivators [PDF]
The study investigated the inhibitory activity of protocetraric and salazinic acids against SARS-CoV-2 3CLpro. The kinetic parameters were determined by microtiter plate-reading fluorimeter using a fluorogenic substrate. The cytotoxic activity was tested
Lorenza Fagnani +10 more
doaj +2 more sources
Theoretical Study on the Antioxidant Activity of Natural Depsidones [PDF]
Mai Van Bay +6 more
doaj +2 more sources
Discovery of Fungus-Derived Nornidulin as a Novel TMEM16A Inhibitor: A Potential Therapy to Inhibit Mucus Secretion in Asthma [PDF]
Pawin Pongkorpsakol,1,* Chantapol Yimnual,2,* Wilasinee Satianrapapong,3 Nichakorn Worakajit,4 Suchada Kaewin,2 Praphatsorn Saetang,5 Vatcharin Rukachaisirikul,5 Chatchai Muanprasat2 1Princess Srisavangavadhana College of Medicine, Chulabhorn ...
Pongkorpsakol P +7 more
doaj +2 more sources
Ultrastructural, Energy-Dispersive X-ray Spectroscopy, Chemical Study and LC-DAD-QToF Chemical Characterization of Cetraria islandica (L.) Ach [PDF]
The lichen Cetraria islandica (L.) Ach. has been used in traditional and modern medicines for its many biological properties such as immunological, immunomodulating, antioxidant, antimicrobial, and anti-inflammatory activities.
Nurlen Manassov +8 more
doaj +2 more sources
The role of lichenized algae in the production of Cladonia verticillaris depsidones, revealed by using alginate-immobilized cells [PDF]
The mycobiont of the lichen Cladonia verticillaris produces two depsidones, protocetraric and fumarprotocetraric acids, in the nature. This last compound is produced from the former depsidone.
Davó, Nuria +3 more
core +3 more sources

