Results 111 to 120 of about 5,859,979 (225)

Supplementation with n-3 long-chain polyunsaturated fatty acids or olive oil in men and women with renal disease induces differential changes in the DNA methylation of FADS2 and ELOVL5 in peripheral blood mononuclear cells [PDF]

, 2014
BACKGROUND: Studies in animal models and in cultured cells have shown that fatty acids can induce alterations in the DNA methylation of specific genes. There have been no studies of the effects of fatty acid supplementation on the epigenetic regulation ...
Burdge, Graham C., Mori, T.A., Karen A Lillycrop, Samuel P Hoile, Rebecca Clarke-Harris, Clarke-Harris, R., Graham C Burdge, Beilin, L.J., Philip C Calder, Lawrence J Beilin, Calder, P.C., Huang, R.C., Lillycrop, Karen A., Trevor A Mori, Hoile, Samuel P., Rae-Chi Huang   +15 more
core   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Titration of C-5 Sterol Desaturase Activity Reveals Its Relationship to Candida albicans Virulence and Antifungal Susceptibility Is Dependent upon Host Immune Status. [PDF]

mBio, 2022
Regan J, DeJarnette C, Luna-Tapia A, Parker JE, Reitler P, Barnett S, Tucker KM, Kelly SL, Palmer GE.   +8 more
europepmc   +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

Association of desaturase activity and C-reactive protein in European children

, 2016
BACKGROUND: Desaturase enzymes influence the fatty acid (FA) composition of body tissues and their activity affects the conversion rate of saturated to monounsaturated FA and of polyunsaturated FA (PUFA) to long-chain PUFA.
Wolters, Maike,, Lissner, Lauren,, Michael Tornaritis, Moreno, Luis A., Pala, Valeria,, Galli, Claudio,, Börnhorst, Claudia, Toomas Veidebaum, Galli, Claudio, Risé, Patrizia, Veidebaum, Toomas,, Fraterman, Arno, Lauren Lissner, Boernhorst, Claudia, Heike Schwarz, Claudio Galli, Claudia Börnhorst, Maike Wolters, Eiben, Gabriele,, Moreno, Luis A, Russo, Paola, Wolfgang Ahrens, Wolters, Maike, The IDEFICS consortium, Russo, Paola,, Fraterman, Arno,, Arno Fraterman, Boernhorst, Claudia,, Luis A. Moreno, Molnar, Dénes, Molnar, Denes,, Gabriele Eiben, Tornaritis, Michael,, Valeria Pala, Paola Russo, Dénes Molnár, Moreno, Luis A.,, Veidebaum, Toomas, Patrizia Risé, Rise, Patrizia,, Ahrens, Wolfgang,, Ahrens, Wolfgang, Schwarz, Heike,, Stefaan De Henauw, Eiben, Gabriele, Pala, Valeria, Tornaritis, Michael, Schwarz, Heike, Lissner, Lauren, De Henauw, Stefaan, De Henauw, Stefaan,   +50 more
core   +1 more source

A lipid‐sensitive food choice behavior influences aging outcomes from a longevity‐promoting diet

The FEBS Journal, EarlyView.
C. elegans are exposed to a variety of bacteria in their natural environment and must be able to distinguish between beneficial and detrimental food sources. We show that C. elegans exposed to the bacterium from their natural habitat, Methylobacterium, disrupts lipid homeostasis, causing worms to avoid this bacterial species and choose the laboratory ...
Nicole L. Stuhr, Carmen M. Ramos, Chris D. Turner, Alexander A. Soukas, Sean P. Curran   +4 more
wiley   +1 more source

Acid-exposed and hypoxic cancer cells do not overlap but are interdependent for unsaturated fatty acid resources

Nature Communications
Cancer cells in acidic tumor regions are aggressive and a key therapeutic target, but distinguishing between acid-exposed and hypoxic cells is challenging.
Katarzyna Głowacka, Sébastien Ibanez, Ophélie Renoult, Perrine Vermonden, Maria Virginia Giolito, Kübra Özkan, Charline Degavre, Léo Aubert, Céline Guilbaud, Florine Laloux-Morris, Elena Richiardone, Jérôme Ambroise, Caroline Bouzin, Davide Brusa, Jonas Dehairs, Johan Swinnen, Cyril Corbet, Yvan Larondelle, Olivier Feron   +18 more
doaj   +1 more source

N-3 Long Chain Fatty Acids Supplementation, Fatty Acids Desaturase Activity, and Colorectal Cancer Risk: A Randomized Controlled Trial. [PDF]

Nutr Cancer, 2022
Murff HJ, Shrubsole MJ, Cai Q, Su T, Dooley JH, Cai SS, Zheng W, Dai Q.   +7 more
europepmc   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

Paving the Way for Plant-Based Bioproduction of (Z)-13-Octadecenoic Moth Pheromone Compounds. [PDF]

Plant Biotechnol J
ABSTRACT Sex pheromones are eco‐friendly agents to control pest insects. Yet, the cost of synthetic pheromone production has restricted their use essentially to high value crops. Plant‐based bioproduction of pheromone compounds offers a promising and sustainable alternative, opening up for the deployment of pheromone‐mediated pest control also in row ...
Liu M, Li H, Jin H, Xiao Y, He P, Tan C, Wang HL, Lassance JM, Löfstedt C, Ding BJ.   +9 more
europepmc   +2 more sources