Results 31 to 40 of about 5,859,979 (225)

Effect of seafood mediated PCB exposure on desaturase activity and PUFA profile in Faroese septuagenarians. [PDF]

open access: yesEnviron Res, 2015
Polychlorinated biphenyl (PCB) exposure may affect serum concentrations of polyunsaturated fatty acids (PUFAs) by inhibiting desaturases ∆5 and ∆6 that drive their synthesis from precursor fatty acids.
Tøttenborg SS   +4 more
europepmc   +2 more sources

The desaturase gene family : an evolutionary study of putative speciation genes in 12 species of Drosophila [PDF]

open access: yes, 2012
The formation and persistence of species are the subject of much debate among biologists. Many species of Drosophila are behaviourally isolated, meaning that heterospecific individuals are not attracted to one another and do not interbreed.
Keays, Maria C.
core   +2 more sources

An alternate pathway to long-chain polyunsaturates: the FADS2 gene product Δ8-desaturates 20:2n-6 and 20:3n-3

open access: yesJournal of Lipid Research, 2009
The mammalian Δ6-desaturase coded by fatty acid desaturase 2 (FADS2; HSA11q12-q13.1) catalyzes the first and rate-limiting step for the biosynthesis of long-chain polyunsaturated fatty acids.
Woo Jung Park   +4 more
doaj   +1 more source

A vertebrate fatty acid desaturase with delta5 and delta6 activities [PDF]

open access: yes, 2001
Δ5 and Δ6 fatty acid desaturases are critical enzymes in the pathways for the biosynthesis of the polyunsaturated fatty acids (PUFA) arachidonic, eicosapentanoic and docosahexanoic acids.
Sargent, John R   +6 more
core   +1 more source

Effects of glucagon and dibutyryl adenosine 3‘, 5‘-cyclic monophosphate on oxidative desaturation of fatty acids in the rat

open access: yesJournal of Lipid Research, 1975
The present work was undertaken to study the effect of anti-insulinic and glycogenolytic factors on the oxidative desaturation of fatty acids. The effects of glucagon and dibutyryl cyclic AMP on the desaturation of linoleic acid to γ-linolenic acid, α ...
I.N. de Gómez Dumm   +2 more
doaj   +1 more source

Characterisation of the delta11-palmitoyl-CoA-desaturase from Spodoptera littoralis (Lepidoptera: Noctuidae)

open access: yes, 1992
One of the key enzymes involved in moth pheromone biosynthesis, palmitoyl-CoA Δ11-desaturase, has been characterized in subcellular fractions from pheromonal glands of adult female Spodoptera littoralis.
Pickett, J. A.   +3 more
core   +1 more source

SCD (stearoyl-CoA desaturase (delta-9-desaturase)) [PDF]

open access: yes, 2016
Despite the presence of monounsaturated fatty acids (MUFA) in the usual diet, these fatty acids may also be synthesized de novo from saturated fatty acids (SFA) through enzymatic desaturase activity (Arregui et al., 2012).
Darabi, Masoud   +2 more
core   +1 more source

Cell density-dependent reduction of dihydroceramide desaturase activity in neuroblastoma cells

open access: yesJournal of Lipid Research, 2012
We applied a metabolic approach to investigate the role of sphingolipids in cell density-induced growth arrest in neuroblastoma cells. Our data revealed that sphingolipid metabolism in neuroblastoma cells significantly differs depending on the cells ...
Stefka D. Spassieva   +5 more
doaj   +1 more source

Regulation of human Δ-6 desaturase gene transcription: identification of a functional direct repeat-1 element

open access: yesJournal of Lipid Research, 2003
The rate-limiting step in 20:4(n-6) and 22:6(n-3) synthesis is the desaturation of 18:2(n-6) and 18:3(n-3) by Δ-6 desaturase. In this report, we demonstrate that n-6 and n-3 PUFAs suppressed the hepatic expression of rodent Δ-6 desaturase by inhibiting ...
Chongren Tang   +3 more
doaj   +1 more source

Nutritional regulation of stearoyl-CoA desaturase in the bovine mammary gland [PDF]

open access: yes, 2011
Increasing the proportion of unsaturated fatty acids (UFA) in milk is believed to be beneficial in terms of human health, thereby increasing the nutritional quality of milk.
Jacobs, A.A.A.
core  

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