Results 111 to 120 of about 473,157 (249)
Management of Highly Sensitized Patients in Renal Transplantation: Prospective Single-Center Study
Background and objectives: In kidney transplantation, immunologic risk assessment was performed through pretransplant measurement of human leukocyte antigen, donor-specific antibodies.
Herish Othman Abdulrahman +1 more
doaj +1 more source
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi +4 more
wiley +1 more source
Highly sensitized kidney transplant candidates are difficult to transplant because anti-human leukocyte antigen (HLA) sensitization restricts access to immunologically compatible organs, as transplantation across donor-specific antibodies (DSA) increases
Stefan Reuter +4 more
doaj +1 more source
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Prostate Cancer Development, Progression, and Therapy
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin +9 more
wiley +1 more source
IntroductionPost-traumatic stress disorder (PTSD) is characterized by intrusive memories and an impaired resilience framework, which often leads to chronic psychological distress.
Tammy Soliman +2 more
doaj +1 more source
Nitric Oxide in Cancer: Mechanisms, Dual Role, and Therapeutic Strategies
Nitric oxide exerts concentration‐dependent dual roles in cancer, functioning as either a tumor promoter or suppressor. This review comprehensively examines NO's multifaceted regulation of tumor biology, including S‐nitrosylation signaling, metabolic reprogramming, immunemodulation, and therapy resistance, and highlights emerging therapeutic strategies
Jia Shao +8 more
wiley +1 more source
ImportancePreformed donor-specific antibodies (pre-DSAs) are a significant immunologic barrier in solid organ transplantation (SOT), yet their association with post-transplant outcomes lacks consensus, limiting standardized clinical management ...
Zhong-yu Kang +4 more
doaj +1 more source

