Results 161 to 170 of about 3,518 (193)
The Relationship Between Lipid Peroxidation and LDL Desialylation in Experimental Atherosclerosis
Toxicology Mechanisms and Methods, 2007 ABSTRACT High serum total cholesterol concentration has been strongly connected with atherosclerosis in numerous studies. Being the main carrier of cholesterol in blood, low-density lipoprotein (LDL) is also the principal lipoprotein causing atherosclerosis.
Volkan Sozer +2 more
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Behaviour of Young and Old Desialylated Rabbit Erythrocytes in vivo
Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1978Young and old rabbit erythrocytes, separated by density gradient centrifugation, were desialylated by neuraminidase treatment and reinjected into the animal after 51Cr labelling. Both red cell populations are quickly removed from the circulation and trapped by the liver; then a large percentage of the young cells reappear in the peripheral blood and ...
BALDUINI, CARLO +3 more
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Chemical synthesis of the desialylated human Cad-antigenic determinant
Carbohydrate Research, 1986Benzyl 2-azido-2-deoxy-beta-D-galactopyranoside was converted into benzyl 2-azido-4,6-O-benzyl-2-deoxy-beta-D-galactopyranoside via benzylidenation, p-methoxybenzylation, acid hydrolysis, benzylation, and selective oxidation. Condensation of 1,2,3,4,6-penta-O-acetyl-beta-D-galactopyranose with benzyl 2-azido-4,6-di-O-benzyl-2-deoxy-beta-D ...
CATELANI, GIORGIO +3 more
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THE EFFECT OF ETHANOL OR HEPATOTOXIN EXPOSURE ON RAT TRANSFERRIN DESIALYLATION
Alcohol and Alcoholism, 1996Serum carbohydrate-deficient transferrin (CDT) is being increasingly used as a biological indicator for excessive alcohol consumption. However, the mechanisms behind the changes in the carbohydrate moiety of transferrin are unclear, although they have been suggested to be mediated by acetaldehyde or liver damage.
K, Löf +6 more
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Glycoconjugate Journal, 2016 Sialic acids (SAs) often exist as the terminal sugars of glycan structures of cell surface glycoproteins and glycolipids. The level and linkages of cell surface SAs, which are controlled by both sialylation and desialylation processes and environment ...
Xue-Long Sun, Huan Nie
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Role of the macrophage galactose lectin in the uptake of desialylated LDL
Atherosclerosis, 2000Desialylated low density lipoprotein (LDL) is rapidly taken up and accumulated by both peripheral blood monocytes and cells isolated from human arterial intima consisting predominantly of smooth muscle cells. It is shown that thioglycollate (TG)-elicited mouse macrophages and mouse peritoneal macrophages stimulated with lipopolysaccharide (LPS) show ...
A L, Bartlett +4 more
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Immunological and Biological Activity of HCG Following Progressive Desialylation
Endocrinology, 1971The effects of progressive removal of sialic acid (desialylation) on the immunological and biological activity of HCG, as measured by radioimmunoassay (RIA), ovarian ascorbic acid depletion assay (OAAD) and ventral prostate weight assay (VPW), have been evaluated.
E V, Van Hall +4 more
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Analysis of genetic variants of transferrin in human serum after desialylation by capillary zone electrophoresis and capillary isoelectric focusing [PDF]
Journal of Separation Science, 2017 Capillary electrophoresis analysis of transferrin in human serum is used to assess genetic variants after desialylation with neuraminidase and iron saturation to reduce the complexity of the transferrin pattern and thus facilitate the recognition of ...
Wolfgang Thormann
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Serum inhibitors of desialylated glycoprotein binding to hepatocyte membranes
Biochimica et Biophysica Acta (BBA) - General Subjects, 1978Identification of the material present in human serum which is responsible for inhibition of binding of desialylated glycoproteins to rat hepatocyte membranes was accomplished by means of affinity chromatography using Sephadex to which the galactose-specific lectin, Ricinus Communis Agglutinin (RCAI) was covalently bound.
J S, Marshall, S, Williams
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Desialylation of surface receptors as a new dimension in cell signaling
Biochemistry (Moscow), 2013Terminal sialic acid residues are found in abundance in glycan chains of glycoproteins and glycolipids on the surface of all live cells forming an outer layer of the cell originally known as glycocalyx. Their presence affects the molecular properties and structure of glycoconjugates, modifying their function and interactions with other molecules ...
A V, Pshezhetsky, L I, Ashmarina
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