Results 171 to 180 of about 3,518 (193)
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Clearance of Desialylated Mouse α-Macroglobulin and Murinoglobulin in the Mouse
The Journal of Biochemistry, 1990Mouse alpha-macroglobulin and murinoglobulin were labeled with 125I and utilized for plasma clearance studies performed with mice. Desialylated murinoglobulin was rapidly cleared from the circulation with a half-life of about 5 min. On the other hand, desialylated alpha-macroglobulin showed a biphasic curve: about half was cleared at a rate similar to ...
K, Abe, K, Yamamoto, H, Sinohara
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Uptake and degradation of desialylated luteinizing hormone by suspended hepatocytes
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1982The uptake and degradation of desialylated human luteinizing hormone (asialo-LH) in suspended hepatocytes have been studied. Asialo-LH was taken up by the asialo-glycoprotein receptor at a rate which was somewhat lower than that of asialo-fetuin. The rate constants and equilibrium binding parameters were similar, but the rate of dissociation of the ...
A, Bleken +3 more
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Desialylation unmasks HPA-9B alloantibodies
Blood, 2023Maria Therese, Ahlen +1 more
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Evaluation of the degree of desialylation of serum C1-inactivator and haemopexin
Clinica Chimica Acta, 1984The calibration curves for evaluating the degree of desialylation of C1-inactivator (sialic acid content 12.5%) and haemopexin (sialic acid content 4%) have been plotted. No desialylation of either glycoprotein occurs in normal subjects. In the patients (liver damage) studied, C1-inactivator is often desialylated, whereas haemopexin is not.
N S, Serbource-Goguel Seta +4 more
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Desialylation of N-Linked Carbohydrate Chain of Fibrinogen
Key Engineering Materials, 2013Acceleration of fibrin polymerization occurs by the cleavage of sialic acids at the nonreducing terminal ends of N-linked carbohydrate chains as well as the cleavage of the entity of carbohydrate chains. In order to characterize and clarify the role of terminal sialic acid in the fibrin polymerization, mixing effects of desialylated fibrinogen with the
Kenji Kubota +3 more
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Hepatic Uptake of Desialylated Testosterone-Oestradiol-Binding Globulin in the Rat
Obstetrical & Gynecological Survey, 1979ABSTRACT Testosterone-oestradiol-binding globulin (TeBG) isolated from bovine serum was desialylated by treatment with neuraminidase and its properties were compared with intact TeBG. No significant differences were observed in the testosterone-binding capacity or antigenic determinant, but electrophoretic mobility of asialo-TeBG decreased ...
Y, Suzuki, H, Sinohara
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Desialylation by neuraminidases in platelets, kiss of death or bittersweet?
Current Opinion in HematologyPurpose of review Loss of surface sialic acid by neuraminidases is known as ‘desialylation’. Platelets are desialylated in bacterial or viral infections, during storage, senescence, various mutations, platelet auto antibodies, hemostasis and shear stress.
Nora, Butta, Dianne E, van der Wal
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Oxidation rates of some desialylated glycoproteins by galactose oxidase
Archives of Biochemistry and Biophysics, 1985Patterns of oxidation of dilute solutions of desialylated fetuin and submaxillary mucin by galactose oxidase have been examined. A significant portion (20-40%) of the terminal galactosyls exposed on the glycoproteins, which theoretically were expected to be accessible to the enzyme, was not oxidized.
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Hepatic clearance of intact and desialylated erythropoietin
American Journal of Physiology-Legacy Content, 1974D W, Briggs, J W, Fisher, W J, George
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