Results 71 to 80 of about 7,325 (186)

Hemidesmosome Mutations Contribute to the Onset and Severity of Acquired Autoimmune Bullous Diseases

MedComm, Volume 7, Issue 3, March 2026.
This study examined hemidesmosome assembly‐related genes in pemphigoid diseases, revealing variants linked to disease onset and severity. Functional analyses, including Caenorhabditis elegans models, Ker‐CT transcriptomics, human proteomics, etc., demonstrated that ITGA6 mutations destabilize hemidesmosomes, disrupt dermal–epidermal adhesion, and ...
Shan Cao, Tianyu Wang, Chen Lv, Shanshan Ma, Gongqi Yu, Qianqian Xia, Tingting Liu, Yueqian Yu, Lele Sun, Xiaoyan Pei, Qing Zhao, Zhenzhen Wang, Chuan Wang, Yongxia Liu, Shengli Chen, Jianwen Wang, Guizhi Zhou, Hong Liu, Yonghu Sun, Furen Zhang   +19 more
wiley   +1 more source

Dysregulated proteolytic cascades in Netherton syndrome: from molecular pathology to preclinical drug testing

The Journal of Pathology, Volume 268, Issue 3, Page 249-262, March 2026.
Abstract Netherton syndrome (NS) is a rare, severe, and often life‐threatening disease for which current therapeutic approaches are limited and show variable effectiveness. NS is characterized by excessive epidermal desquamation that results in a highly defective epidermal barrier, constitutive skin inflammation, allergies, and hair abnormalities.
Eleni Zingkou, Evangelos Bisyris, Georgios Pampalakis, Georgia Sotiropoulou   +3 more
wiley   +1 more source

Case Report: Delayed recurrence of staphylococcal scalded skin syndrome in an extremely low birth weight infant

Frontiers in Pediatrics
Preterm infants have well-documented deficiencies in their innate and adaptive immune responses, which are indirectly correlated with their gestational age at birth.
Sara M. Hooper, Camille M. Fung, Camille M. Fung, Carrie Torr, Carrie Torr, Shelley M. Lawrence, Shelley M. Lawrence   +6 more
doaj   +1 more source

Sita‐ and saxagliptin use and autoantibodies to autoimmune bullous diseases: A cross‐sectional study

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 4, Page e227-e230, April 2026.
Sören Dräger, Claudia Kauderer, Svenja Meyhöfer, Leonie Dräger, Jens U. Marquardt, Ralf J. Ludwig, Stephan Arndt, Katharina Boch, Katja Bieber   +8 more
wiley   +1 more source

Desmoglein-2-integrin Beta-8 interaction regulates actin assembly in endothelial cells: deregulation in systemic sclerosis.

PLoS ONE, 2013
BackgroundThe inability of endothelial cells of patients affected by the diffuse form of Systemic sclerosis (SSc) to perform angiogenesis is a marker of the disease.
Betti Giusti, Francesca Margheri, Luciana Rossi, Ilaria Lapini, Alberto Magi, Simona Serratì, Anastasia Chillà, Anna Laurenzana, Lucia Magnelli, Lido Calorini, Francesca Bianchini, Gabriella Fibbi, Rosanna Abbate, Mario Del Rosso   +13 more
doaj   +1 more source

IgG/IgA pemphigus with differing regional presentations

JAAD Case Reports, 2022
Hok Fai Cheng, MBBS(HK), MRCP(UK), FHKAM(Medicine), Wai Ki Tsoi, MBBS(UK), MRCP(UK), Mandy Mang Ting Ng, FHKAM(Pathology), FRCPA, Wai Ki Ip, PhD, FFScRCPA, D(ABMLI), King Man Ho, FHKAM(Medicine), FRCP(Edin)   +4 more
doaj   +1 more source

Investigation of SNPs in the porcine desmoglein 1 gene

BMC Veterinary Research, 2007
Background Desmoglein 1 (DSG1) is the target protein in the skin disease exudative epidermitis in pigs caused by virulent strains of Staphylococcus hyicus. The exfoliative toxins produced by S.
Andresen Lars, Daugaard Lise, Fredholm Merete   +2 more
doaj   +1 more source

A Case of Palmoplantar Vesiculobullous Lesions

JEADV Clinical Practice, Volume 5, Issue 1, Page 315-318, March 2026.
Ali Abid, Kelvin Truong, Jing Jing Li, Artiene Tatian   +3 more
wiley   +1 more source

Polymorphic Mucocutaneous Eruption and Septic Shock in a 75‐Year‐Old Man

JEADV Clinical Practice, Volume 5, Issue 1, Page 323-325, March 2026.
Sweta Subhadarshani, Brad R. Woodie, Kerith E. Spicknall   +2 more
wiley   +1 more source

Dysphagia and history of vegetative plaques

JAAD Case Reports, 2022
Anna Catinis, BA, Tyson Meaux, MD
doaj   +1 more source