Smaller desmosomes are seen in the skin of pemphigus patients with anti-desmoglein 1 antibodies but not in patients with anti-desmoglein 3 antibodies. [PDF]
G. van der Wier+4 more
semanticscholar +5 more sources
Proteomic analysis of skin invasion by blood fluke larvae. [PDF]
BackgroundDuring invasion of human skin by schistosome blood fluke larvae (cercariae), a multicellular organism breaches the epidermis, basement membrane, and dermal barriers of skin.
Braschi, Simon+7 more
core +1 more source
Paraneoplastic pemphigus with clinical features of lichen planus associated with low-grade B cell lymphoma [PDF]
BACKGROUND: Neoplasia-induced lichen planus is described as a cell-mediated reaction to unknown epithelial antigens. Paraneoplastic pemphigus (PNP), characterized by the presence of a specific array of autoantibodies, probably represents a different form
Black, M+4 more
core +1 more source
RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis. [PDF]
Cilia-related proteins are believed to be involved in a broad range of cellular processes. Retinitis pigmentosa GTPase regulator interacting protein 1-like (RPGRIP1L) is a ciliary protein required for ciliogenesis in many cell types, including epidermal ...
Yeon Ja Choi+17 more
doaj +1 more source
Glutenbedingte Hauterkrankungen: Klinik, Diagnostik und Therapie
Zusammenfassung Glutenbedingte Erkrankungen stellen ein Spektrum verschiedener klinischer Erscheinungsformen dar, die durch die Aufnahme von Gluten bei genetisch anfälligen Personen ausgelöst werden. Zu den glutenbedingten Erkrankungen gehören die Zöliakie und die Nicht‐Zöliakie‐Glutensensitivität (NCGS). Glutenbedingte Erkrankungen zeichnen sich durch
Dario Didona+2 more
wiley +1 more source
A global perspective of arrhythmogenic right ventricular cardiomyopathy. [PDF]
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a progressive inherited heart disease characterized by ventricular arrhythmias and sudden cardiac death especially in the young. ARVC has been traditionally associated with the Mediterranean basin,
Alhashemi, M+3 more
core +1 more source
Background A number of autoimmune diseases have been clinically and pathologically characterized. In contrast, target antigens have been identified only in a few cases and, in these few cases, the knowledge of the exact epitopic antigenic sequence is ...
Sinha Animesh A+5 more
doaj +1 more source
Pathological IgE Production in Inborn Errors of Immunity and Beyond
ABSTRACT In this review, we examine different mechanisms for the generation of pathological IgE through the study of inborn errors of immunity (IEI). In particular, we focus on IEIs that are susceptible to atopic disease, such as severe eczema, eosinophilia, and/or food anaphylaxis; this group of approximately 50 genes has been coined primary atopic ...
Cindy S. Ma, Peter S. Hsu
wiley +1 more source
Ear, nose and throat manifestations in pemphigus vulgaris [PDF]
Pemphigus vulgaris (PV) is an autoimmune disease characterized by mucocutaneous intraepithelial blisters and pathogenic autoantibodies against desmoglein 3. There are two clinical forms: mucosal (MPV) and mucocutaneous (MCPV).
España, A. (Agustín)+6 more
core +1 more source
Topographical variations in the skin barrier and their role in disease pathogenesis
Unlike the gut, the skin appears uniform at first glance. However, histological and molecular biological research has revealed significant regional variations in the composition and function of its main barrier elements. In this review, we describe the topographical differences of four barrier elements in healthy skin: microbiome, chemical, physical ...
Z. Dajnoki+5 more
wiley +1 more source