Results 91 to 100 of about 13,115 (209)

Paraneoplastic pemphigus with clinical features of lichen planus associated with low-grade B cell lymphoma [PDF]

, 2005
BACKGROUND: Neoplasia-induced lichen planus is described as a cell-mediated reaction to unknown epithelial antigens. Paraneoplastic pemphigus (PNP), characterized by the presence of a specific array of autoantibodies, probably represents a different form
Black, M, Coelho, S, Figueiredo, A, Reis, JP, Tellechea, O   +4 more
core   +1 more source

Ear, nose and throat manifestations in pemphigus vulgaris [PDF]

, 2007
Pemphigus vulgaris (PV) is an autoimmune disease characterized by mucocutaneous intraepithelial blisters and pathogenic autoantibodies against desmoglein 3. There are two clinical forms: mucosal (MPV) and mucocutaneous (MCPV).
España, A. (Agustín), Fernández-González, S. (Secundino), Marquina, M. (Miren), Olmo-López, J. (Julio) del, Pretel, M. (Maider), Ruba, D. (David), Sanchez-Ibarrola, A. (Alfonso)   +6 more
core   +1 more source

Comparative Analysis of HEK293 Genomic Variability

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 436-448, February 2026.
An investigation of how HEK293‐derived cell lines adapt genetically to different culture conditions and environmental pressures: despite distinct phenotypes and cultivation histories, comparative whole‐genome analyses of established HEK293 variants as well as newly suspension‐adapted cells revealed a shared, common set of mutations linked to cell ...
Georg Smesnik, Nikolaus Virgolini, Maria Toth, Astrid Dürauer, Nicole Borth   +4 more
wiley   +1 more source

A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. [PDF]

, 2015
Keratin intermediate filaments (KIFs) protect the epidermis against mechanical force, support strong adhesion, help barrier formation, and regulate growth.
Adams, Alam, Alvarado, Arin, Baris, Bianchi, Bligh, Bunick, Bär, Böttinger, Candi, Candi, Capetanaki, Chan, Chernoivanenko, Christina B. Brazel, Chung, Coulombe, Coulombe, Crowe, Dennis R. Roop, Duan, Egberts, Ellis, Epand, Fessing, Fontanesi, Fuchs, Fuchs, Gendronneau, Geng, Habtezion, Haines, Hamanaka, Hans Binder, Hardman, Helenius, Henry Löffler-Wirth, Herrmann, Hesse, Hoefs, Homberg, Homberg, Hornig-Do, Hoste, Hue-Tran Hornig-Do, Huebner, Jamal-Eddine Bouameur, Janina Bär, Jaquemar, Jarnik, Jayaprakash, Kalinin, Kato, Kawasaki, Kerns, Kim, Kim, Kloepper, Koch, Kröger, Kröger, Kuramoto, Kypriotou, Laatsch, Lane, Langbein, Lessard, Lim, Loschke, Macdiarmid, Magin, Matsui, Matsuki, McAleer, Mor-Vaknin, Nakamichi, Nestle, Nicole Schwarz, Nishizawa, Norlén, Oji, Owens, Palmer, Panjwani, Paradies, Peter Seibel, Preethi Vijayaraj, Quigley, Reichelt, Reichelt, Reichelt, Rice, Rice, Rice, Robert H. Rice, Roop, Rorke, Roth, Roth, Rowland, Rudolf E. Leube, Rudolf J. Wiesner, Sabharwal, Sakaguchi, Samuelov, Samuelov, Sandilands, Sandra Heller, Schmuth, Schweizer, Schäfer, Schäfer, Segre, Segre, Seltmann, Seltmann, Seltmann, Sevilla, Signorelli, Simpson, Singla, Smith, Susanne Brodesser, Szeverenyi, Sören Thiering, Takahashi, Tamai, Tao, Tasseva, Tatsuta, Thomas M. Magin, Vijayaraj, Vijayaraj, Vinod Kumar, Wallace, Watt, Yao, Yu, Zeeuwen, Özbalci   +140 more
core   +1 more source

Cytokine Milieu Relevant to Atopic Dermatitis Enhances Epidermal Trypsin‐Like Serine Protease Activity, Which Is Pharmacologically Suppressed in Human Keratinocytes

The Journal of Dermatology, EarlyView.
Shiori Onishi, Yohei Yasutomi, Onon Tsedendorj, Shin Morizane   +3 more
wiley   +1 more source

A Genome‐Wide Association Study Reveals Desmoglein‐2 Predominance in Japanese Arrhythmogenic Cardiomyopathy

Journal of Arrhythmia, Volume 42, Issue 1, February 2026.
A GWAS of Japanese arrhythmogenic cardiomyopathy identified a strong signal near DSG2, exceeding the genome‐wide significance of p = 5 × 10–8 (red line). This signal disappeared after excluding carriers of rare DSG2 variants. Stratified analyses indicate that the association reflects a DSG2‐D494A‐mediated synthetic effect driven predominantly by this ...
Taisuke Ishikawa, Kyuto Sonehara, Keiko Sonoda, Kenshi Hayashi, Koichi Kato, Satoshi Nagase, Kengo Kusano, Takeshi Aiba, Minoru Horie, Seiko Ohno, Yukinori Okada, Naomasa Makita   +11 more
wiley   +1 more source

Hypothesis: Ephrin–Eph Signaling Pathways Provide Novel Targets for Accelerated Re‐Epithelialization of Cutaneous Wounds

BioEssays, Volume 48, Issue 1, January 2026.
In distal limb wounds on the horse, the proliferative phase of repair often produces excessive granulation tissue that delays healing by impeding keratinocyte migration from wound margins. This essay examines the basis for the hypothesis that ephrin–Eph signaling pathways that stimulate keratinocyte migration provide novel targets for re‐establishing ...
Rodolfo D. Vicetti Miguel, Mohan Liu, Gabriel J. Campion, Thomas L. Cherpes   +3 more
wiley   +1 more source

A Systematic Review on the Role of Desmoglein 1 and Desmoglein 3 in Etiopathogenesis and Metastasis of Oral Cancer

Journal of Indian Academy of Oral Medicine and Radiology
Background: Desmosomal proteins have a fundamental role in cellular adhesion as they not only maintain cellular homeostasis but also regulate cellular activities like proliferation, differentiation, and migration.
Pavan Kumar Yellarthi, Arvind Muthukrishnan, Gandikota Raghurama Rao, Sandhya Pavankumar, Divya Uppala   +4 more
doaj   +1 more source

Identification of Autoreactive B Cell Subpopulations in Peripheral Blood of Autoimmune Patients With Pemphigus Vulgaris

Frontiers in Immunology, 2019
Pemphigus vulgaris (PV) is a rare blistering disease caused by IgG autoantibodies against the epidermal adhesion molecules desmoglein (Dsg)3 and Dsg1 providing a well-characterized paradigm of an antibody-mediated organ-specific autoimmune disease. In PV
Robert Pollmann, Elias Walter, Thomas Schmidt, Jens Waschke, Michael Hertl, Christian Möbs, Rüdiger Eming   +6 more
doaj   +1 more source

Functional Effects of the TMEM43 Ser358Leu Mutation in the Pathogenesis of Arrhythmogenic Right Ventricular Cardiomyopathy [PDF]

, 2012
Background: The Ser358Leu mutation in TMEM43, encoding an inner nuclear membrane protein, has been implicated in arrhythmogenic right ventricular cardiomyopathy (ARVC). The pathogenetic mechanisms of this mutation are poorly understood.
Ahmad, Ferhaan, McDonough, Barbara Anne, Rajkumar, Revathi, Seidman, Christine Edry, Sembrat, John C   +4 more
core   +5 more sources