Non-classical forms of pemphigus: pemphigus herpetiformis, IgA pemphigus, paraneoplastic pemphigus and IgG/IgA pemphigus [PDF]
The pemphigus group comprises the autoimmune intraepidermal blistering diseases classically divided into two major types: pemphigus vulgaris and pemphigus foliaceous.
Adriana Maria Porro+134 more
core +4 more sources
Clinical Features and Current Therapeutic Approaches to Monilethrix: A Systematic Review
ABSTRACT Monilethrix is a rare congenital hair disorder characterized by fragile, beaded hair shafts due to mutations in various keratin or desmoglein 4 genes. A systematic review of 24 studies (16 pediatric only, 3 mixed adult and pediatric, 3 adult only, and 2 unspecified) evaluating various treatment modalities identified topical and oral minoxidil ...
Adam C. Yu+2 more
wiley +1 more source
Rituximab therapy improves recalcitrant Pemphigus vulgaris [PDF]
Pemphigus is a severe life-threatening blistering disease associated with autoantibodies against cell adhesion proteins desmogleins 1 and 3. Patients with severe pemphigus commonly show high rates of relapse after conventional immunosuppressive therapy ...
Balighi, Kamran+7 more
core
Cutaneous Biology: In vivo blockade of pemphigus vulgaris acantholysis by inhibition of intracellular signal transduction cascades [PDF]
Pemphigus vulgaris (PV) is an autoimmune disease characterized by mucocutaneous intraepithelial blisters and pathogenic autoantibodies against desmoglein 3.
Diaz, L.A. (L. A.)+6 more
core +1 more source
Development of a Desmocollin-3 Active Mouse Model Recapitulating Human Atypical Pemphigus
Pemphigus vulgaris (PV) is a life-threatening mucocutaneous autoimmune blistering disease. It is often associated with autoantibodies to the desmosomal adhesion proteins Desmoglein 3 (DSG3) and Desmoglein 1 (DSG1).
Roberta Lotti+6 more
doaj +1 more source
Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model
Pemphigus is a chronic autoimmune skin blistering disease, characterized by acantholysis and by the production of autoantibodies directed against the structural desmosomal proteins desmoglein 1 (DSG1) and/or DSG3.
Uta Katharina Radine+14 more
doaj +1 more source
The Role of Desmoglein-3 in the Diagnosis of Squamous Cell Carcinoma of the Lung [PDF]
Results from several microarray-based studies have led to the identification of up-regulated expression levels of the DSG3 gene in pulmonary squamous cell carcinomas (SQCCs). The purpose of this study was to determine the role of DSG3 expression in the diagnosis of SQCCs of the lung and to compare DSG3 with p63, CK5, and CK6, as markers of squamous ...
George Vasmatzis+6 more
openaire +3 more sources
Autoimmun betegségekben szerepet játszó új, diagnosztikus epitópok, valamint Fc receptorhoz kötődő és effektor funkciót kiváltó IgG Fc peptidkimérák azonosítása, szintézise és funkcionális jellemzése = Identification, synthesis and functional characterisation of new, diagnostic epitopes in autoimmune diseases, and of IgG Fc peptide chimeras binding to Fc receptor and triggering effector function [PDF]
Autoimmun hólyagos bőrbetegségekre jellemző B- és T-sejt epitóppeptideket szintetizáltunk szilárdfázisú peptidszintézissel, Fmoc/tBu stratégiával. A peptideket tisztítottuk, azonosítottuk.
Bartos, Ádám+6 more
core
Background A number of autoimmune diseases have been clinically and pathologically characterized. In contrast, target antigens have been identified only in a few cases and, in these few cases, the knowledge of the exact epitopic antigenic sequence is ...
Sinha Animesh A+5 more
doaj +1 more source
Hailey‐Hailey Disease: An Updated Review With a Focus on Therapeutic Mechanisms
ABSTRACT Background Hailey‐Hailey disease (HHD), or familial benign chronic pemphigus, is a rare autosomal dominant genodermatosis characterized by chronic, painful, erythematous, erosive plaques and fissures at sites of friction such as the neck, axilla, groin, and perineum.
Mahesh Mathur+4 more
wiley +1 more source