Results 91 to 100 of about 18,739,280 (231)
Development of a Desmocollin-3 Active Mouse Model Recapitulating Human Atypical Pemphigus
Frontiers in Immunology, 2019 Pemphigus vulgaris (PV) is a life-threatening mucocutaneous autoimmune blistering disease. It is often associated with autoantibodies to the desmosomal adhesion proteins Desmoglein 3 (DSG3) and Desmoglein 1 (DSG1).
Roberta Lotti +6 more
doaj +1 more source
Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model
Frontiers in Medicine, 2022 Pemphigus is a chronic autoimmune skin blistering disease, characterized by acantholysis and by the production of autoantibodies directed against the structural desmosomal proteins desmoglein 1 (DSG1) and/or DSG3.
Uta Katharina Radine +14 more
doaj +1 more source
Incidence of P200 pemphigoid: A nationwide study
Journal of the European Academy of Dermatology and Venereology, EarlyView.The anti‐LAMB4 cell‐based immunoassay is a new serological technique that is far superior to dermal immunoblotting for detecting autoantibodies directed against the P200 protein. This method allows a re‐evaluation of the incidence of P200 pemphigoid, which appears to be considerably more frequent than epidermolysis bullosa acquisita.
Fabienne Jouen +7 more
wiley +1 more source
049 Phenotypic and functional analysis of autoreactive CD4+ T cell responses against Desmoglein 3 epitopes in pemphigus vulgaris [PDF]
, 2022 Karolin Wieber, D. Didona, M. Hertl
openalex +1 more source
Pediatric Dermatology, EarlyView.ABSTRACT Erythrokeratodermia cardiomyopathy (EKC) syndrome is a rare autosomal dominant disorder characterized by generalized erythrokeratoderma and progressive dilated cardiomyopathy, caused by pathogenic variants in the SR6 domain of desmoplakin (DSP).
Sepideh Hamzehlou +7 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A, three‐dimensional representation of cardiac intercalated disk, reduced to a 100‐partition, computationally efficient network representation. B, ion dynamics within intercalated disk extracellular cleft space. C, rapid pacing leads to localized conduction block in tissue with regions of perturbed intercalated disk (ID ...
Nicolae Moise +6 more
wiley +1 more source
International Journal of Dermatology, Volume 65, Issue 4, Page 797-805, April 2026.ABSTRACT Introduction Hailey‐Hailey disease (HHD) is a rare genodermatosis caused by mutations in the ATP2C1 gene that codes for SPCA1, a calcium transporter in the epidermis. HHD impairs quality of life, and no curative treatment exists. Methods To confirm the efficacy and safety of CO2 laser in HHD, we conducted a randomized, prospective, controlled ...
Javier Antoñanzas +7 more
wiley +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2009 Anti-desmoglein 3 and 1 autoantibodies are involved in the pathogenesis of pemphigus diseases. Our objective was to assess the value of ELISA in the diagnosis of pemphigus and its correlation with the severity of pemphigus vulgaris.
Mortazavi Hossein +8 more
doaj
Bullous Wells’ syndrome successfully treated with omalizumab
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Giulia Ciccarese +7 more
wiley +1 more source
Strategies for Monitoring Serum Protein Degradation With an Antibody Array‐Based Technology
Journal of Clinical Laboratory Analysis, Volume 40, Issue 5, March 2026.This study analyzed the stability of 480 proteins in human serum samples collected from 10 healthy donors and incubated at room temperature for 0–48 h. Antibody array profiling revealed significant time‐dependent degradation of 201 proteins. Subsequent physicochemical and functional enrichment analyses demonstrated that the degraded proteins were ...
Yanlin Wang +7 more
wiley +1 more source