Results 81 to 90 of about 7,948 (164)

Desmoglein as a Target in Skin Disease and Beyond

, 2012
Much of the original research on desmosomes and their biochemical components was through analysis of skin and mucous membranes. The identification of desmogleins 1 and 3, desmosomal adhesion glycoproteins, as targets in pemphigus, a fatal autoimmune ...
Stanley, John R., John R. Stanley, Masayuki Amagai, Amagai, Masayuki   +3 more
core   +1 more source

Up-regulation of ST18 in pemphigus vulgaris drives a self-amplifying p53-dependent pathomechanism resulting in decreased desmoglein 3 expression. [PDF]

Sci Rep, 2022
Assaf S, Vodo D, Malovitski K, Mohamad J, Bergson S, Feller Y, Malki L, Sarig O, Sprecher E.   +8 more
europepmc   +1 more source

Desmoglein-3 [PDF]

, 2020
openaire   +1 more source

Peripheral tolerance by Treg via constraining OX40 signal in autoreactive T cells against desmoglein 3, a target antigen in pemphigus. [PDF]

Proc Natl Acad Sci U S A, 2021
Iriki H, Takahashi H, Wada N, Nomura H, Mukai M, Kamata A, Ito H, Yamagami J, Matsui T, Kurebayashi Y, Mise-Omata S, Nishimasu H, Nureki O, Yoshimura A, Hori S, Amagai M.   +15 more
europepmc   +1 more source

Desmoglein Isotype Expression in the Hair Follicle and its Cysts Correlates with Type of Keratinization and Degree of Differentiation

, 2003
Within stratified squamous epithelia, such as the epidermis, desmogleins are generally expressed in a differentiation-specific manner. Similar to the epidermis, the hair follicle is compartmentalized into a hierarchy of cell types based on their level of
Stanley, John R., Cotsarelis, George, Wu, Hong   +2 more
core   +1 more source

Evolving Mechanisms in the Pathophysiology of Pemphigus Vulgaris: A Review Emphasizing the Role of Desmoglein 3 in Regulating p53 and the Yes-Associated Protein. [PDF]

Life (Basel), 2021
Rehman A, Huang Y, Wan H.
europepmc   +1 more source

Non-Desmoglein Antibodies in Patients With Pemphigus Vulgaris

, 2018
Pemphigus vulgaris (PV) is a potentially life-threatening mucocutaneous autoimmune blistering disease. Patients develop non-healing erosions and blisters due to cell–cell detachment of keratinocytes (acantholysis), with subsequent suprabasal ...
Manuel Valdebran, Sergei A. Grando, Kyle T. Amber   +2 more
core   +1 more source

Caspase-activation powers anti-Desmoglein 3-induced acantholysis in human epidermis. [PDF]

Cell Death Discov
Schmidt MF, Feoktistova MA, Panayotova-Dimitrova D, Buhl EM, Boor P, Ruhl T, Waschke J, Tikkanen R, Röcken M, Baron JM, Yazdi AS.   +10 more
europepmc   +2 more sources

Desmoglein ELISA in the Diagnosis of Pemphigus and Its Correlation with the Severity of Pemphigus Vulgaris

, 2009
Anti-desmoglein 3 and 1 autoantibodies are involved in the pathogenesis of pemphigus diseases. Our objective was to assess the value of ELISA in the diagnosis of pemphigus and its correlation with the severity of pemphigus vulgaris.
Sedaghat Mojtaba, Chams-Davatchi Cheyda, Valikhani Mahin, Vasheghani-Farahani Amir, Shahdi Majid, Daneshpazhooh Maryam, S.Naraghi Zahra, Mortazavi Hossein, Amirzargar Ali Akbar   +8 more
core  

Correction: Zakrzewicz et al. Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus? Cells 2022, 11, 942. [PDF]

Cells, 2022
Zakrzewicz A, Würth C, Beckert B, Feldhoff S, Vanderheyden K, Foss S, Andersen JT, Haard H, Verheesen P, Bobkov V, Tikkanen R.   +10 more
europepmc   +1 more source