Results 81 to 90 of about 18,202,744 (191)
Frontiers in Immunology, 2019 Pemphigus vulgaris (PV) is a rare blistering disease caused by IgG autoantibodies against the epidermal adhesion molecules desmoglein (Dsg)3 and Dsg1 providing a well-characterized paradigm of an antibody-mediated organ-specific autoimmune disease. In PV
Robert Pollmann +6 more
doaj +1 more source
A Case Report of a Patient With Recalcitrant Pemphigus Vulgaris Treated With Rituximab
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT Pemphigus vulgaris may demonstrate differential treatment responses across disease sites. In this case, cutaneous lesions responded to high‐dose corticosteroids, whereas refractory oral disease required rituximab to achieve remission, highlighting the need for individualized, multimodal therapy to achieve sustained disease control.
Mahlatse Cordelia Kgokolo +3 more
wiley +1 more source
Integrated Immune, Epithelial and Lipid Pathways in NSAID‐Exacerbated Respiratory Disease
Clinical and Translational Allergy, Volume 16, Issue 8, August 2026.ABSTRACT NSAID‐exacerbated respiratory disease (N‐ERD) is a chronic inflammatory disorder characterized by asthma, chronic rhinosinusitis with nasal polyps and respiratory reactions to cyclooxygenase‐1 inhibiting nonsteroidal anti‐inflammatory drugs (NSAID).
Piotr Szatkowski, Lucyna Mastalerz
wiley +1 more source
Colocalization of desmoglein-2 and integrin-beta8 in N-MVECs.
, 2013 A) Immunostaining of N-MVECs with anti-desmoglein-2 and anti-integrin-beta8 antibodies (nuclei stained with DAPI) in a single N-MVEC (upper row) and in a group of N-MVECs (lower row).
Simona Serratì (220041) +13 more
core +1 more source
The expressions of desmoglein 1 and 3 according to chronologic skin aging
, 2018 Background: Desmogleins ate transmembrane glycoproteins of the desmosome which provide mechanical strength to epithelial tissue. Desmogleins have so far, been implicated in several diseases such as pemphigus, striate palmoplantar keratoderma, 4S and ...
최유원
core +1 more source
Unbiased screening identifies regulators of cell-cell adhesion and treatment options in pemphigus
Nature CommunicationsCell-cell junctions, and specifically desmosomes, are crucial for robust intercellular adhesion. Desmosomal function is compromised in the autoimmune blistering skin disease pemphigus vulgaris.
Henriette Franz +13 more
doaj +1 more source
Non-pathogenic Anti-Desmoglein 3 IgG Autoantibodies in Fogo Selvagem [PDF]
, 2006 The endemic form of pemphigus foliaceus, fogo selvagem, is caused by IgG autoantibodies directed against desmoglein 1 (Dsg1). Hilario-Vargas and his colleagues describe a high prevalence of IgG autoantibodies against Dsg3, the target antigen of pemphigus
Amagai, Masayuki
core +1 more source
, 2002 Pemphigus encompasses a group of autoimmune blistering diseases with circulating pathogenic autoantibodies recognizing several proteins, including the desmosomal cadherin, desmoglein 3. Targeted disruption of the Dsg3 gene by homologous recombination (
Pulkkinen, L +6 more
core +1 more source
Journal of Clinical and Translational Science, 2017 OBJECTIVES/SPECIFIC AIMS: Pemphigus vulgaris (PV) is a potentially fatal blistering disease caused by autoantibodies to the keratinocyte adhesion protein desmoglein 3.
Nina Ran +3 more
doaj +1 more source
Desmoglein-2 interaction is crucial for cardiomyocyte cohesion and function.
, 2014 AIMS: We determined the contribution of the desmosomal cadherin desmoglein-2 to cell-cell cohesion in cardiomyocytes. In the intercalated disc, providing mechanical strength and electrical communication between adjacent cardiomyocytes, desmoglein-2 is ...
Syrris, P +20 more
core +1 more source