Desmoglein as a Target in Skin Disease and Beyond [PDF]
, 2012 Much of the original research on desmosomes and their biochemical components was through analysis of skin and mucous membranes. The identification of desmogleins 1 and 3, desmosomal adhesion glycoproteins, as targets in pemphigus, a fatal autoimmune ...
Stanley, John R. +3 more
core +1 more source
Comparative Transcriptome Analysis Identifies Desmoglein-3 as a Potential Oncogene in Oral Cancer Cells. [PDF]
Cells, 2023 Wan H, Teh MT, Mastroianni G, Ahmad US.
europepmc +1 more source
Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
T cell autoimmunity and immune regulation to desmoglein 3, a pemphigus autoantigen. [PDF]
J Dermatol, 2023 Takahashi H, Iriki H, Asahina Y.
europepmc +1 more source
iRHOM2 in skin disease and oesophageal cancer [PDF]
, 2015 PhDMutations in RHBDF2, the gene encoding inactive rhomboid protein iRHOM2, result in the dominantly inherited condition Tylosis with oesophageal cancer (TOC). TOC causes plamoplantar keratoderma, oral precursor lesions and up to a 95 % life-time risk of
Etheridge, Sarah
core +2 more sources
Attenuation of OX40 signaling suppression by age disrupts peripheral deletion of CD4+ T cells specific for the epidermal autoantigen desmoglein 3. [PDF]
Immun Ageing, 2023 Iriki H +6 more
europepmc +1 more source
Circulating Antibodies Against DSG1 and DSG3 in Patients with Oral Lichen Planus: A Scoping Review
AntibodiesOral Lichen Planus (OLP) is a chronic autoimmune disease with potential overlap with Pemphigus Vulgaris (PV), particularly in erosive forms. Desmoglein 1 and 3 are transmembrane glycoproteins of desmosomes, typically involved in PV.
Domenico De Falco +5 more
doaj +1 more source
Antibodies against the Celiac Peptide Recognize Desmoglein 1
, 2013 (A) Sequence homology between the celiac peptide and cell junction proteins. The peptide sequence was compared with known protein sequences using the BLASTP via the NCBI BLAST network service (colons indicate identity and asterisks indicate conservative ...
Giuseppe Tridente (65728) +10 more
core +1 more source
Faster IgG4 Depletion Kinetics Observed for Anti-Desmoglein 3 Autoantibodies Following Rituximab Treatment in Patients with Pemphigus Vulgaris. [PDF]
Acta Derm Venereol, 2022 Boch K +8 more
europepmc +1 more source
Dermatology ReportsThe discovery of the role of Bruton’s Tyrosine Kinase (BTK) in inflammation and autoimmunity has recently led to the development of BTK inhibitors for the treatment of autoimmune diseases, including pemphigus vulgaris.
Christian Ciolfi +5 more
doaj