Results 61 to 70 of about 7,948 (164)

A Spontaneous Deletion within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype

, 2015
Desmoglein 3 is a transmembrane component of desmosome complexes that mediate epidermal cell-to-cell adhesion and tissue integrity. Antibody blockade of desmoglein 3 function in pemphigus vulgaris patients leads to skin blistering (acantholysis) and oral
Kountikov, Evgueni I., Tedder, Thomas F., Poe, Jonathan C., Maclver, Nancie J., Rathmell, Jeffrey C.   +4 more
core   +1 more source

Postnatal Lethality of P-Cadherin/Desmoglein 3 Double Knockout Mice: Demonstration of a Cooperative Effect of these Cell Adhesion Molecules in Tissue Homeostasis of Stratified Squamous Epithelia

, 2000
To investigate the cooperativity of different cell adhesion molecules in maintaining the structural integrity of the epidermis, we have generated mice deficient for both a classical cadherin, P-cadherin, and a desmosomal cadherin, desmoglein 3.
Stanley, John R., Lenox, Jennifer M., Radice, Glenn L., Lieberman, Melanie, Koch, Peter J., Mahoney, My G.   +5 more
core   +1 more source

Comparative Transcriptome Analysis Identifies Desmoglein-3 as a Potential Oncogene in Oral Cancer Cells. [PDF]

Cells, 2023
Wan H, Teh MT, Mastroianni G, Ahmad US.
europepmc   +1 more source

Determining the potential of desmoglein 3 as a sensitive and specific immunohistochemical marker for the detection of micrometastasis in patients with primary oral squamous cell carcinoma

, 2016
Aim of the study : Despite advances in surgical and radiotherapy techniques, the presence of lymph node metastasis drastically decreases the survival rate of patients with primary oral squamous cell carcinoma (OSCC).
Anita Spadigam, Shruti Nagvekar, Anita Dhupar   +2 more
core   +1 more source

T cell autoimmunity and immune regulation to desmoglein 3, a pemphigus autoantigen. [PDF]

J Dermatol, 2023
Takahashi H, Iriki H, Asahina Y.
europepmc   +1 more source

Antibodies against the Celiac Peptide Recognize Desmoglein 1

, 2013
(A) Sequence homology between the celiac peptide and cell junction proteins. The peptide sequence was compared with known protein sequences using the BLASTP via the NCBI BLAST network service (colons indicate identity and asterisks indicate conservative ...
Giuseppe Tridente (65728), Enrico Valletta (65730), Giovanna Zanoni (65727), Caterina Bason (12871), Antonio Puccetti (12876), Claudio Lunardi (12868), Simona Sivori (65729), Ruggero Beri (12874), Roberto Corrocher (12875), Riccardo Navone (12872), Marzia Dolcino (12869)   +10 more
core   +1 more source

Attenuation of OX40 signaling suppression by age disrupts peripheral deletion of CD4⁺ T cells specific for the epidermal autoantigen desmoglein 3. [PDF]

Immun Ageing, 2023
Iriki H, Mukai M, Asahina Y, Kubo Y, Ito H, Amagai M, Takahashi H.   +6 more
europepmc   +1 more source

Immunization with desmoglein 3 induces non-pathogenic autoantibodies in mice. [PDF]

PLoS One, 2021
Boch K, Dräger S, Zillikens D, Hudemann C, Hammers CM, Patzelt S, Schmidt E, Langan EA, Eming R, Ludwig RJ, Bieber K.   +10 more
europepmc   +1 more source

The expressions of desmoglein 1 and 3 according to chronologic skin aging

, 2018
Background: Desmogleins ate transmembrane glycoproteins of the desmosome which provide mechanical strength to epithelial tissue. Desmogleins have so far, been implicated in several diseases such as pemphigus, striate palmoplantar keratoderma, 4S and ...
최유원
core  

Faster IgG4 Depletion Kinetics Observed for Anti-Desmoglein 3 Autoantibodies Following Rituximab Treatment in Patients with Pemphigus Vulgaris. [PDF]

Acta Derm Venereol, 2022
Boch K, Langan EA, Van Beek N, Kridin K, Schmidt E, Zillikens D, Ludwig RJ, Hammers CM, Bieber K.   +8 more
europepmc   +1 more source