Results 51 to 60 of about 7,948 (164)
Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone
JEADV Clinical Practice, Volume 5, Issue 2, Page 415-424, June 2026.ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri +2 more
wiley +1 more source
Organoids: From Bench to Bedside Applications
MedComm, Volume 7, Issue 6, June 2026.Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
British Journal of Haematology, Volume 208, Issue 6, Page 2036-2046, June 2026.The spectrum of Castleman diseases has expanded over the past three decades. The phenotype of the diseases varies not only among the three major types but also according to the patient ancestry. Summary Under the Castleman disease (CD) eponym, three distinct diseases sharing common pathological features have been described over time.
Eric Oksenhendler +4 more
wiley +1 more source
Staphylococcus hyicus exfoliative toxins selectively digest porcine desmoglein 1
, 2005 Virulent strains of Staphylococcus hyicus can cause exudative epidermitis in pigs. The major symptom of this disease is exfoliation of the skin in the upper stratum spinosum. Exfoliation of the skin is strongly associated with exfoliative toxin including
Komatsuzawa, H. +6 more
core +1 more source
Pediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.This graphical abstract illustrates the conceptual framework linking rare and common diseases in pediatric allergy and immunology through precision medicine. On the left, rare conditions such as inborn errors of immunity and primary atopic disorders represent well‐defined monogenic models that reveal fundamental mechanisms of immune dysregulation.
Riccardo Castagnoli +26 more
wiley +1 more source
Colocalization of desmoglein-2 and integrin-beta8 in N-MVECs.
, 2013 A) Immunostaining of N-MVECs with anti-desmoglein-2 and anti-integrin-beta8 antibodies (nuclei stained with DAPI) in a single N-MVEC (upper row) and in a group of N-MVECs (lower row).
Simona Serratì (220041) +13 more
core +1 more source
Journal of Indian Academy of Oral Medicine and RadiologyAbstract Background: Desmosomal proteins have a fundamental role in cellular adhesion as they not only maintain cellular homeostasis but also regulate cellular activities like proliferation, differentiation, and migration. Desmosomal protein expression, namely desmoglein 1 (DSG 1) and desmoglein 3 (DSG 3), is known to
Pavan Kumar Yellarthi +4 more
openaire +2 more sources
IgA pemphigus showing IgA antibodies to desmoglein 1 and 3
, 2016 Background: IgA pemphigus is a rare autoimmune vesiculo-pustular skin disease. Only approximately 70 cases have been reported to date. We report a case of IgA pemphigus with IgA antibodies to desmoglein 1 (Dsg1) and desmoglein 3 (Dsg3).
Lilia Laadher +5 more
core +1 more source
The structural basis for the integrity of adenovirus Ad3 dodecahedron [PDF]
, 2012 During the viral life cycle adenoviruses produce excess capsid proteins. Human adenovirus serotype 3 (Ad3) synthesizes predominantly an excess of free pentons, the complexes of pentameric penton base and trimeric fiber proteins, which are responsible for
Fender, Pascal +36 more
core +1 more source
Do serum prolactin levels correlate with antibodies against desmoglein in pemphigus vulgaris?
, 2016 BACKGROUND: Pemphigus vulgaris is a chronic inflammatory disease of skin, the etiology of which is not completely known. Despite the latter, anti-desmoglein antibodies play a proven role in the pathogenesis.
Alireza Asemi Esfahani +13 more
core +1 more source