Results 41 to 50 of about 7,257 (168)

YAP Inhibition by Verteporfin Causes Downregulation of Desmosomal Genes and Proteins Leading to the Disintegration of Intercellular Junctions

open access: yesLife, 2022
The Hippo-YAP pathway serves as a central signalling hub in epithelial tissue generation and homeostasis. Yes-associated protein (YAP) is an essential downstream transcription cofactor of this pathway, with its activity being negatively regulated by ...
Yunying Huang   +4 more
doaj   +1 more source

Dipeptidyl Peptidase‐4 Inhibitor Use and Risk of Pemphigus Vulgaris and Foliaceus: A Retrospective Cohort Study Using Databases of the Korea National Health Insurance Claims and the National Health Screening Examination

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Although population‐based studies have reported an increased risk of bullous pemphigoid and pemphigus associated with dipeptidyl peptidase‐4 (DPP‐4) inhibitors, there is limited, well‐designed epidemiological evidence for pemphigus vulgaris (PV), which has only been supported by case reports thus far.
Jaein Lee, Jae Hyun Bae, Seokyung Hahn
wiley   +1 more source

Cyclophosphamide is associated with long‐term treatment‐free remission in patients with pemphigus

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objective Pemphigus treatment has seen significant advancements, yet long‐term remission remains a challenge. Comparative data on the long‐term effectiveness of available therapies are limited. We compared 10‐year relapse rates in pemphigus patients treated with azathioprine or cyclophosphamide plus high‐dose IV corticosteroids ...
Bettina Santler   +5 more
wiley   +1 more source

High-grade non-small cell lung carcinoma: a comparative analysis of the phenotypic profile in small biopsies with the corresponding postoperative material

open access: yesPolish Journal of Pathology, 2019
The most recent classification of the lung cancer expanded the diagnostic criteria of its histological subtypes and included its immunophenotypic profile.
Jolanta Szade   +3 more
doaj   +1 more source

Repositioning Non‐Ablative Fractional Lasers ‐ Molecular and Histological Insights from a scoping review

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Near‐infrared non‐ablative fractional lasers (NAFL) are established for skin rejuvenation and scar treatment and have attracted interest for their expanding therapeutic potential. This scoping review aims to revisit and reposition NAFL within a fluence‐dependent continuum of tissue modulation, based on evidence from 27 studies of lasers ...
Guy Erlich   +4 more
wiley   +1 more source

Diagnostic Utility of BIOCHIP Mosaic Indirect Immunofluorescence in Intraepidermal Autoimmune Blistering Diseases

open access: yesClinical Dermatology Review
Background: Pemphigus is a chronic intraepidermal autoimmune blistering disorder (IABD) characterized by the presence of circulating autoantibodies against desmogleins 1and 3.
Padmini Chitradurga Vijayasarathy   +1 more
doaj   +1 more source

IgA pemphigus showing IgA antibodies to desmoglein 1 and 3

open access: yesDermatology Practical & Conceptual, 2016
Background: IgA pemphigus is a rare autoimmune vesiculo-pustular skin disease. Only approximately 70 cases have been reported to date. We report a case of IgA pemphigus with IgA antibodies to desmoglein 1 (Dsg1) and desmoglein 3 (Dsg3).
Salama Hegazy   +5 more
doaj   +1 more source

Bullous pemphigoid associated with milia, increased serum IgE, autoantibodies against desmogleins, and refractory treatment in a young patient [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2017
: Bullous pemphigoid is a blistering autoimmune disease characterized by two hemidesmosomal proteins (anti-BP180 and 230). Pemphigus, by contrast, is characterized by two autoantibodies (anti-desmoglein 1 and 3).
Shu Ding   +5 more
doaj   +1 more source

Detection of anti-desmoglein antibodies in oral lichen planus: What do we know so far

open access: yesFrontiers in Immunology, 2022
Oral lichen planus (OLP) is an inflammatory disease of the oral mucosa. Clinically, two main subsets are described, namely non-erosive and erosive OLP. While non-erosive OLP is usually responsive to local therapies, erosive OLP is often refractory also ...
Dario Didona, Michael Hertl
doaj   +1 more source

Incidence of P200 pemphigoid: A nationwide study

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
The anti‐LAMB4 cell‐based immunoassay is a new serological technique that is far superior to dermal immunoblotting for detecting autoantibodies directed against the P200 protein. This method allows a re‐evaluation of the incidence of P200 pemphigoid, which appears to be considerably more frequent than epidermolysis bullosa acquisita.
Fabienne Jouen   +7 more
wiley   +1 more source

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