Detection of autoantibodies against recombinant desmoglein 1 and 3 molecules in patients with pemphigus vulgaris: correlation with disease extent at the time of diagnosis and during follow-up [PDF]
The recent availability of cDNA clones for pemphigus antigens has allowed the production of recombinant desmoglein 1 and desmoglein 3 molecules and the development of an ELISA approach in order to determine levels of antibodies to them.
ALAIBAC, MAURO SALVATORE ALESSANDRO +6 more
core +2 more sources
Rituximab in pemphigus foliaceous with autoantibodies against both Desmoglein 1 and Desmoglein 3 [PDF]
ejd.2011.1288 Auteur(s) : Rodrigo CARVALHO1 rodrigoaraujocarvalho@gmail.com, Paula MAIO1, Daniela CUNHA1, Isabel FREITAS1, Ana AFONSO2, Jorge CARDOSO1 1 Department of Dermatology and Venereology, Curry Cabral Hospital, Lisbon, Portugal 2 Department of Pathology, Curry Cabral Hospital, Lisbon, Portugal Reprints.: R. CARVALHO Pemphigus foliaceous (PF) is
Rodrigo CARVALHO +5 more
openaire +1 more source
Review on DSG2 (desmoglein 2), with data on DNA, on the protein encoded, and where the gene is ...
M Yashiro, Yashiro, M
core +1 more source
Desmoglein autoantibodies and disease severity in pemphigus patients – correlations and discrepancies [PDF]
Aim: To assess the correlation between the levels of anti-desmoglein-1 and anti-desmoglein-3 autoantibodies and disease severity in pemphigus patients.
Tsvetana I. Abadjieva +9 more
core +1 more source
Prognostic Significance of Desmoglein 2 and Desmoglein 3 in Esophageal Squamous Cell Carcinoma
Desmogleins (DSGs) are major members among the desmosomal cadherins critically involved in cell-cell adhesion and the maintenance of normal tissue architecture in epithelia. Reports exploring links of DSG family member expression with cancers are few and vary.
Wang-Kai, Fang +8 more
openaire +3 more sources
HLA class II antigens in Croatian patients with pemphigus vulgaris and their correlation with anti-desmoglein antibodies [PDF]
Pemphigus vulgaris (PV) is an acquired autoimmune blistering disease characterized by the production of autoantibodies targeting desmosomal cadherins, primarily desmoglein 1 and desmoglein 3, leading to acantholysis. The etiology of PV is multifactorial,
Mislav Mokos +2 more
core +2 more sources
Successful Treatment of Severe Adult Linear IgA Dermatosis Using Dupilumab
ABSTRACT Linear IgA dermatosis (LAD) is a rare autoimmune subepidermal bullous dermatosis, characterised by the presence of erythematous vesiculobullous lesions arranged in rosettes or herpetiform clusters. The standard treatment involves the administration of dapsone, followed by sulfasalazine, and general corticosteroid therapy, often in combination ...
Célia Delesalle +7 more
wiley +1 more source
Investigation of SNPs in the porcine desmoglein 1 gene [PDF]
Background Desmoglein 1 (DSG1) is the target protein in the skin disease exudative epidermitis in pigs caused by virulent strains of Staphylococcus hyicus. The exfoliative toxins produced by S.
Fredholm Merete +10 more
core +1 more source
Pemphigus vulgaris is an autoimmune blistering disease caused by autoantibodies against desmoglein 3, a member of the desmosomal cadherin family. These autoantibodies recognize conformation-dependent epitopes on desmoglein 3.
Nishikawa, Takeji +5 more
core +1 more source
Case Report: Desmoglein-3 Gene Mutation Leading to Airway Compromise in Fraternal Twin Infants
The desmoglein 3 18q11 gene mutation has not been well described in humans, except for a few case reports. The desmoglein 3 gene controls a transmembrane component of the desmosome complex that mediates epidermal cell adhesion and integrity of the ...
Deserres, Lianne +3 more
core +1 more source

