The transmembrane domain of the desmosomal cadherin desmoglein-1 governs lipid raft association to promote desmosome adhesive strength. [PDF]
Zimmer SE +3 more
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Deletion of the Epidermal Protease KLK5 Aggravates the Symptoms of Congenital Ichthyosis CDSN-nEDD. [PDF]
Zingkou E +5 more
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Porcine Corneal Models as Translational Platforms for Innovative Therapies: Current Insights and Future Directions. [PDF]
NĂ¡poles P, Faria M, Campos EJ.
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3D organotypic skin models recapitulate autoantibody-driven pemphigus pathomechanisms and targeted therapeutic response. [PDF]
Zhai H +7 more
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Molecular Pathogenesis of Arrhythmogenic Cardiomyopathy: Mechanisms and Therapeutic Perspectives. [PDF]
Popa E, Hostiuc S.
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Clinical and genetic study of a family with epidermolysis bullosa simplex caused by a novel <i>KRT5</i> gene mutation c.987C>G (p.Asn329Lys). [PDF]
Zhang R, Chen X, Wang Z, Xu C, Li S.
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Desmosomes in heart and skin: friends or foes?
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Er:YAG laser ablation: Possibly a valuable tool in the management of refractory Hailey-Hailey disease. [PDF]
Rogner D.
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New evidence from blocking desmosomal adhesion with anti-adhesion peptides reveals a role for desmosomes in cell positioning in morphogenesis. Desmosomal adhesion is necessary for the stability of adherens junctions in epithelial cell sheets. Knockout and mis-expression of desmosomal cadherins in mice suggests that they may function directly or ...
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Desmosomes in acquired disease [PDF]
Desmosomes are cell-cell junctions that mediate adhesion and couple the intermediate filament cytoskeleton to sites of cell-cell contact. This architectural arrangement integrates adhesion and cytoskeletal elements of adjacent cells. The importance of this robust adhesion system is evident in numerous human diseases, both inherited and acquired, which ...
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