Results 41 to 50 of about 20,510 (243)
Histopathological Features and Protein Markers of Arrhythmogenic Cardiomyopathy
Frontiers in Cardiovascular Medicine, 2021 Arrhythmogenic cardiomyopathy (ACM) is a heritable heart muscle disease characterized by syncope, palpitations, ventricular arrhythmias and sudden cardiac death (SCD) especially in young individuals.
Carlos Bueno-Beti, Angeliki Asimaki
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Desmosomes: A light microscopic and ultrastructural analysis of desmosomes in odontogenic cysts
Journal of Oral and Maxillofacial Pathology, 2014 Desmosomes together with adherens junctions represent the major adhesive cell-cell junctions of epithelial cells. Any damage to these junctions leads to loss of structural balance.The present study was designed to analyze the desmosomal junctions in different odontogenic cysts and compare them with their corresponding hematoxylin and eosin (H and E ...
Pratima Raju +2 more
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Genetic Animal Models for Arrhythmogenic Cardiomyopathy
Frontiers in Physiology, 2020 Arrhythmogenic cardiomyopathy has been clinically defined since the 1980s and causes right or biventricular cardiomyopathy associated with ventricular arrhythmia.
Brenda Gerull +2 more
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The keratin–desmosome scaffold: pivotal role of desmosomes for keratin network morphogenesis
Cellular and Molecular Life Sciences, 2019 Desmosome-anchored keratin intermediate filaments (KFs) are essential for epithelial coherence. Yet, desmosomal KF attachment and network organization are still unexplored in vivo.
M. Moch +3 more
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Desmosome assembly and dynamics [PDF]
Trends in Cell Biology, 2013 Desmosomes are intercellular junctions that anchor intermediate filaments (IFs) to the plasma membrane, forming a supracellular scaffold that provides mechanical resilience to tissues. This anchoring function is accomplished by specialized members of the cadherin family and associated cytoskeletal linking proteins, which together form a highly ...
Oxana Nekrasova, Kathleen J. Green
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Desmosomes in Developing Human Epidermis
Dermatology Research and Practice, 2010 Desmosomes play important roles in the cell differentiation and morphogenesis of tissues. Studies on animal models have greatly increased our knowledge on epidermal development while reports on human developing skin are rare due to the difficult ...
Sirkku Peltonen +2 more
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Paradoxical Roles of Desmosomal Components in Head and Neck Cancer
Biomolecules, 2021 Desmosomes are intercellular adhesion complexes involved in various aspects of epithelial pathophysiology, including tissue homeostasis, morphogenesis, and disease development.
Yin-Qiao Liu +3 more
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Desmosomes and Intermediate Filaments: Their Consequences for Tissue Mechanics.
Cold Spring Harbor Perspectives in Biology, 2017 Adherens junctions (AJs) and desmosomes connect the actin and keratin filament networks of adjacent cells into a mechanical unit. Whereas AJs function in mechanosensing and in transducing mechanical forces between the plasma membrane and the actomyosin ...
M. Hatzfeld, René Keil, T. Magin
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Biology, 2020 Tumor resistance to therapy is associated with the 3D organization and peculiarities of the tumor microenvironment, of which intercellular adhesion is a key participant. In this work, the abundance of contact proteins was compared in SKOV-3 and SKOV-3.ip
Olga M. Kutova +6 more
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Expression and Significance of Cadherins and Its Subtypes in Development and Progression of Oral Cancers: A Review [PDF]
Journal of Clinical and Diagnostic Research, 2015 Cadherins are a family of transmembranous glycoproteins responsible for calcium-dependent intercellular adhesion. Absence or loss of function of E-cadherin leads to the disappearance of epithelial characteristics of the cells and generates higher ...
Yogesh Chand Rajwar +5 more
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