Results 31 to 40 of about 4,329 (200)

Desmosterol: A natural product derived from macroalgae modulates inflammatory response and oxidative stress pathways in intestinal epithelial cells

Frontiers in Immunology, 2023
The serum level of cholesterol and its biosynthetic intermediates are critical indicators to access metabolism-related disorders in humans and animals.
Huan Qu, Qiufang Zong, Ping Hu, Zhaojian Li, Haifei Wang, Haifei Wang, Shenglong Wu, Shenglong Wu, Hao-Yu Liu, Hao-Yu Liu, Wenbin Bao, Wenbin Bao, Demin Cai, Demin Cai   +13 more
doaj   +1 more source

Chronic Aripiprazole and Trazodone Polypharmacy Effects on Systemic and Brain Cholesterol Biosynthesis

Biomolecules, 2023
The concurrent use of several medications is a common practice in the treatment of complex psychiatric conditions. One such commonly used combination is aripiprazole (ARI), an antipsychotic, and trazodone (TRZ), an antidepressant.
Zeljka Korade, Allison Anderson, Marta Balog, Keri A. Tallman, Ned A. Porter, Karoly Mirnics   +5 more
doaj   +1 more source

Effects of metabolic rate and sperm competition on the fatty-acid composition of mammalian sperm [PDF]

, 2016
The sperm membrane is a key structure affecting sperm function and thus reproductive success. Spermatozoa are highly specialized and differentiated cells that undergo a long series of processes in the male and female reproductive tracts until they reach ...
Delbarco-Trillo, Javier, Roldán, Eduardo R. S.   +1 more
core   +1 more source

Analysis of bioactive oxysterols in newborn mouse brain by LC/MS

Journal of Lipid Research, 2012
Unesterified cholesterol is a major component of plasma membranes. In the brain of the adult, it is mostly found in myelin sheaths, where it plays a major architectural role.
Anna Meljon, Spyridon Theofilopoulos, Cedric H.L. Shackleton, Gordon L. Watson, Norman B. Javitt, Hans-Joachim Knölker, Ratni Saini, Ernest Arenas, Yuqin Wang, William J. Griffiths   +9 more
doaj   +1 more source

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. [PDF]

, 2018
Oxidized phospholipids (OxPL) are ubiquitous, are formed in many inflammatory tissues, including atherosclerotic lesions, and frequently mediate proinflammatory changes 1 .
Binder, Christoph J, Bowden, Karen, Diehl, Cody, Gaddis, Dalia E, Glass, Christopher K, Gonen, Ayelet, Hedrick, Catherine C, Hung, Ming-Yow, Ley, Klaus, MacDonald, Jeffrey G, Mellon, Pamela L, Miller, Yury I, Määttä, Antti, Pattison, Jennifer, Peterson, Kirk L, Prohaska, Thomas A, Que, Xuchu, Sun, Xiaoli, Tsimikas, Sotirios, Witztum, Joseph L, Yeang, Calvin, Ylä-Herttuala, Seppo   +21 more
core   +1 more source

Formal Synthesis of Squalamine from Desmosterol.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Kazuo, Okumura, Yutaka, Nakamura, Seiji, Takeuchi, Isao, Kato, Yoshinori, Fujimoto, Nobuo, Ikekawa   +5 more
openaire   +3 more sources

The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts [PDF]

, 2018
K
Balogh, István, Kim, Hye-Young H., Koczok, Katalin, Korade, Zeljka, Liu, Wei, Mirnics, Károly, Porter, Ned A., Tallman, Keri A., Xu, Libin   +8 more
core   +1 more source

Biosynthesis of squalene and sterols by rat aorta

Journal of Lipid Research, 1971
The synthesis of nonsaponifiable compounds from radioactive mevalonate by segments of adult rat aorta was studied in vitro. The labeled products consisted largely of substances with the chromatographic and chemical behavior of squalene, lanosterol ...
MARIE M. DALY
doaj   +1 more source

Low density lipoprotein cholesterol is inversely correlated with abdominal visceral fat area: a magnetic resonance imaging study [PDF]

, 2011
Background Visceral Fat Area (VFA) is an independent predictor of coronary disease. While low density lipoprotein cholesterol (LDL-C) is used to determine risk and guide therapy, its accuracy fails in obese patients who may have low LDL-C despite high ...
Michel R Hoenig, Gary Cowin, Raymond Buckley, Christine McHenery, Alan Coulthard   +4 more
core   +1 more source

Preparation of desmosterol from fucosterol.

Chemical and Pharmaceutical Bulletin, 1976
Desmosteryl acetate, a useful key intermediate for synthesis of the metabolites of vitamin D3, was synthesized from fucosterol by two routes ; (1) 24, 28-epoxyfucosteryl acetate was treated with solid acids such as zeolite, silica-alumina and alumina-boria to give desmosteryl acetate in a yield of 16%-40%, (2) dehydration of 24-hydroxycholesteryl ...
TORU TAKESHITA, SACHIO ISHIMOTO, NOBUO IKEKAWA   +2 more
openaire   +2 more sources